Forschungszentrum Borstel
Forschungszentrum Borstel


Pathologie des Universitätsklinikums Schleswig-Holstein, Campus Lübeck und des Leibniz-Forschungszentrums Borstel
Standort Borstel

Klinische und Experimentelle Pathologie


Krupar, R, Hautmann, MG, Pathak, RR, Varier, I, McLaren, C, Gaag, D, Hellerbrand, C, Evert, M, Laban, S, Idel, C, Sandulache, V, Perner, S, Bosserhoff, AK & Sikora, AG 2018, 'Immuno-metabolic determinants of chemoradiotherapy response and survival in head and neck squamous cell carcinoma' AMERICAN JOURNAL OF PATHOLOGY, Bd 188, Nr. 1, S. 72-83. DOI: 10.1016/j.ajpath.2017.09.013

Jappe, U, Minge, S, Kreft, B, Ludwig, A, Przybilla, B, Walker, A, Varga, R, Seidel, P, Biedermann, T, Anemüller, W, Kromminga, A, Ruëff, F, Merk, H, Wagner, N, Treudler, R, Worm, M, Waldmann, I, Saloga, J, Becker, WM, Goldmann, T, Platts-Mills, TA & Homann, A 2018, 'Meat allergy associated with α-Gal - Closing diagnostic gaps by anti-α-Gal IgE immune profiling' ALLERGY, Bd 73, Nr. 1, S. 93-105. DOI: 10.1111/all.13238


Schmitt, A, Knittel, G, Welcker, D, Yang, T-P, George, J, Nowak, M, Leeser, U, Buttner, R, Perner, S, Peifer, M & Reinhardt, HC 2017, 'ATM deficiency is associated with sensitivity to PARP1 and ATR inhibitors in lung adenocarcinoma' Cancer Research, Bd 77, Nr. 11, S. 3040-3056. DOI: 10.1158/0008-5472.CAN-16-3398

Marwitz, S & Goldmann, T 2017, 'Back into focus: tumour-associated macrophages and their role in immune checkpoint inhibition' Translational Cancer Research, Bd 6, Nr. supp6. DOI: 10.21037/tcr.2017.07.18

Schecher, S, Walter, B, Falkenstein, M, Macher-Goeppinger, S, Stenzel, P, Krümpelmann, K, Hadaschik, B, Perner, S, Kristiansen, G, Duensing, S, Roth, W & Tagscherer, KE 2017, 'Cyclin K dependent regulation of Aurora B affects apoptosis and proliferation by induction of mitotic catastrophe in prostate cancer' INTERNATIONAL JOURNAL OF CANCER , Bd 141, Nr. 8, S. 1643-1653. DOI: 10.1002/ijc.30864

Zhang, Y, Wang, X, Perner, S, Bánkfalvi, Á & Schlücker, S 2017, 'Effect of antigen retrieval methods on non-specific binding of anti-body-metal nanoparticle conjugates on FFPE tissue' ANALYTICAL CHEMISTRY . DOI: 10.1021/acs.analchem.7b03144

Watz, H, Uddin, M, Pedersen, F, Kirsten, A-M, Goldmann, T, Stellmacher, F, Groth, E, Larsson, B, Böttcher, G, Malmgren, A, Kraan, M & Rabe, KF 2017, 'Effects of the CXCR2 antagonist AZD5069 on lung neutrophil recruitment in asthma' PULMONARY PHARMACOLOGY & THERAPEUTICS , Bd 45, S. 121-123. DOI: 10.1016/j.pupt.2017.05.012

Deng, M, Brägelmann, J, Kryukov, I, Saraiva-Agostinho, N & Perner, S 2017, 'FirebrowseR: an R client to the Broad Institute's Firehose Pipeline' Database : the journal of biological databases and curation, Bd 2017, S. pii baw160. DOI: 10.1093/database/baw160

Ritter, M, Tamadaho, RS, Feid, J, Vogel, W, Wiszniewsky, K, Perner, S, Hoerauf, A & Layland, LE 2017, 'IL-4/5 signalling plays an important role during Litomosoides sigmodontis infection, influencing both immune system regulation and tissue pathology in the thoracic cavity' INTERNATIONAL JOURNAL FOR PARASITOLOGY, Bd 47, Nr. 14, S. 951-960. DOI: 10.1016/j.ijpara.2017.06.009

Laban, S, Giebel, G, Klümper, N, Schröck, A, Doescher, J, Spagnoli, G, Thierauf, J, Theodoraki, M-N, Remark, R, Gnjatic, S, Krupar, R, Sikora, AG, Litjens, G, Grabe, N, Kristiansen, G, Bootz, F, Schuler, PJ, Brunner, C, Brägelmann, J, Hoffmann, TK & Perner, S 2017, 'MAGE expression in head and neck squamous cell carcinoma primary tumors, lymph node metastases and respective recurrencesimplications for immunotherapy' Oncotarget, Bd 8, Nr. 9, S. 14719-14735. DOI: 10.18632/oncotarget.14830

Offermann, A, Vlasic, I, Vogel, W, Ruiz, C, Zellweger, T, Rentsch, CA, Hagedorn, S, Behrends, J, Nowak, M, Merseburger, A, Bubendorf, L, Kirfel, J, Duensing, S, Shaikhibrahim, Z & Perner, S 2017, 'MED15 overexpression in prostate cancer arises during androgen deprivation therapy via PI3K/mTOR signaling' Oncotarget, Bd 8, Nr. 5, S. 7964-7976. DOI: 10.18632/oncotarget.13860

Klümper, N, Syring, I, Vogel, W, Schmidt, D, Müller, SC, Ellinger, J, Shaikhibrahim, Z, Brägelmann, J & Perner, S 2017, 'Mediator Complex Subunit MED1 Protein Expression Is Decreased during Bladder Cancer Progression' Frontiers in Medicine, Bd 4, Nr. 30. DOI: 10.3389/fmed.2017.00030

Kaufhold, I, Osbahr, S, Shima, K, Marwitz, S, Rohmann, K, Drömann, D, Goldmann, T, Dalhoff, K & Rupp, J 2017, 'Nontypeable Haemophilus influenzae (NTHi) directly interfere with the regulation of E-cadherin in lung epithelial cells' MICROBES AND INFECTION , Bd 19, Nr. 11, S. 560-566. DOI: 10.1016/j.micinf.2017.07.002

Brägelmann, J, Klümper, N, Offermann, A, von Mässenhausen, A, Böhm, D, Deng, M, Queisser, A, Sanders, C, Syring, I, Merseburger, AS, Vogel, W, Sievers, E, Vlasic, I, Carlsson, J, Andrén, O, Brossart, P, Duensing, S, Svensson, MA, Shaikhibrahim, Z, Kirfel, J & Perner, S 2017, 'Pan-cancer analysis of the Mediator complex transcriptome identifies CDK19 and CDK8 as therapeutic targets in advanced prostate cancer' CLINICAL CANCER RESEARCH , Bd 23, Nr. 7, S. 1829-1840. DOI: 10.1158/1078-0432.CCR-16-0094

Wang, H, Schaefer, T, Konantz, M, Braun, M, Varga, Z, Paczulla, AM, Reich, S, Jacob, F, Perner, S, Moch, H, Fehm, T, Kanz, L, Schulze-Osthoff, K & Lengerke, C 2017, 'Prominent oncogenic roles of EVI1 in breast carcinoma' Cancer Research, Bd 77, Nr. 8, S. 2148-2160. DOI: 10.1158/0008-5472.CAN-16-0593

von Klot, CA, Kuczyk, MA, Boeker, A, Reuter, C, Imkamp, F, Herrmann, TRW, Tezval, H, Kramer, MW, Perner, S & Merseburger, AS 2017, 'Role of free testosterone levels in patients with metastatic castration-resistant prostate cancer receiving second-line therapy' Oncology Letters, Bd 13, Nr. 1, S. 22-28. DOI: 10.3892/ol.2016.5392

Lautenschläger, I, Wong, YL, Sarau, J, Goldmann, T, Zitta, K, Albrecht, M, Frerichs, I, Weiler, N & Uhlig, S 2017, 'Signalling mechanisms in PAF-induced intestinal failure' Scientific Reports, Bd 7, Nr. 1, S. 13382. DOI: 10.1038/s41598-017-13850-x

Pfalzgraff, A, Heinbockel, L, Su, Q, Brandenburg, K & Weindl, G 2017, 'Synthetic anti-endotoxin peptides inhibit cytoplasmic LPS-mediated responses' BIOCHEMICAL PHARMACOLOGY , Bd 140, S. 64-72. DOI: 10.1016/j.bcp.2017.05.015

Müller, T, Fay, S, Vieira, RP, Karmouty-Quintana, H, Cicko, S, Ayata, K, Zissel, G, Goldmann, T, Lungarella, G, Ferrari, D, Di Virgilio, F, Robaye, B, Boeynaems, J-M, Blackburn, MR & Idzko, M 2017, 'The purinergic receptor subtype P2Y2 mediates chemotaxis of neutrophils and fibroblasts in fibrotic lung disease' Oncotarget, Bd 8, Nr. 22, S. 35962-35972. DOI: 10.18632/oncotarget.16414


Affolter, A, Muller, M-F, Sommer, K, Stenzinger, A, Zaoui, K, Lorenz, K, Wolf, T, Sharma, S, Wolf, J, Perner, S, Weber, K-J, Freier, K, Plinkert, PK, Hess, J & Weichert, W 2016, 'Targeting irradiation-induced mitogen-activated protein kinase activation in vitro and in an ex vivo model for human head and neck cancer' Head and neck journal for the sciences and specialities of the head and neck, Bd 38 Suppl, Nr. 1, S. E2049-61. DOI: 10.1002/hed.24376

Biancosino, C, Krüger, M, Vollmer, E & Welker, L 2016, 'Intraoperative fine needle aspirations - diagnosis and typing of lung cancer in small biopsies: challenges and limitations' Diagnostic pathology, Bd 11, Nr. 1, S. 59. DOI: 10.1186/s13000-016-0510-6

Brandenburg, K, Heinbockel, L, Correa-Vargas, W & Lohner, K 2016, 'Peptides with dual mode of action: Killing bacteria and preventing endotoxin-induced sepsis' BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, Bd 1858, Nr. 5, S. 971-979. DOI: 10.1016/j.bbamem.2016.01.011

Brandenburg, K, Heinbockel, L, Correa-Vargas, W, Fukuoka, S, Gutsmann, T, Zähringer, U & Koch, MHJ 2016, 'Supramolecular structure of enterobacterial wild-type lipopolysaccharides (LPS), fractions thereof, and their neutralization by Pep19-2.5' Journal of Structural Biology, Bd 194, Nr. 1, S. 68-77. DOI: 10.1016/j.jsb.2016.01.014

Deng, M, Brägelmann, J, Schultze, JL & Perner, S 2016, 'Web-TCGA: an online platform for integrated analysis of molecular cancer data sets'  BIOINFORMATICS , Bd 17, Nr. 1, S. 72. DOI: 10.1186/s12859-016-0917-9

Ganbat, D, Seehase, S, Richter, E, Vollmer, E, Reiling, N, Fellenberg, K, Gaede, KI, Kugler, C & Goldmann, T 2016, 'Mycobacteria infect different cell types in the human lung and cause species dependent cellular changes in infected cells' BMC PULMONARY MEDICINE, Bd 16, Nr. 1, S. 19. DOI: 10.1186/s12890-016-0185-5

Goldmann, T, Kugler, C, Reinmuth, N, Vollmer, E & Reck, M 2016, 'PD-L1 copy number gain in Non Small Cell Lung Cancer defines a new subset of patients for anti PD-L1 therapy' Annals of oncology : official journal of the European Society for Medical Oncology / ESMO, Bd 27, Nr. 1, S. 206-7. DOI: 10.1093/annonc/mdv510

Herrtwich, L, Nanda, I, Evangelou, K, Nikolova, T, Horn, V, [Unbekannt], S, Erny, D, Stefanowski, J, Rogell, L, Klein, C, Gharun, K, Follo, M, Seidl, M, Kremer, B, Münke, N, Senges, J, Fliegauf, M, Aschman, T, Pfeifer, D, Sarrazin, S, Sieweke, MH, Wagner, D, Dierks, C, Haaf, T, Ness, T, Zaiss, MM, Voll, RE, Deshmukh, SD, Prinz, M, Goldmann, T, Hölscher, C, Hauser, AE, Lopez-Contreras, AJ, Grün, D, Gorgoulis, V, Diefenbach, A, Henneke, P & Triantafyllopoulou, A 2016, 'DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas' CELL, Bd 167, Nr. 5, S. 1264. DOI: 10.1016/j.cell.2016.09.054

Hoefflin, R, Lahrmann, B, Warsow, G, Hübschmann, D, Spath, C, Walter, B, Chen, X, Hofer, L, Macher-Goeppinger, S, Tolstov, Y, Korzeniewski, N, Duensing, A, Grüllich, C, Jäger, D, Perner, S, Schönberg, G, Nyarangi-Dix, J, Isaac, S, Hatiboglu, G, Teber, D, Hadaschik, B, Pahernik, S, Roth, W, Eils, R, Schlesner, M, Sültmann, H, Hohenfellner, M, Grabe, N & Duensing, S 2016, 'Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity' Nature communications, Bd 7, S. ncomms11845. DOI: 10.1038/ncomms11845

Kraus, D, Reckenbeil, J, Perner, S, Winter, J & Probstmeier, R 2016, 'Expression Pattern of Matrix Metalloproteinase 20 (MMP20) in Human Tumors' Anticancer research, Bd 36, Nr. 6, S. 2713-8.

Luedeke, M, Rinckleb, AE, FitzGerald, LM, Geybels, MS, Schleutker, J, Eeles, RA, Teixeira, MR, Cannon-Albright, L, Ostrander, EA, Weikert, S, Herkommer, K, Wahlfors, T, Visakorpi, T, Leinonen, KA, Tammela, TLJ, Cooper, CS, Kote-Jarai, Z, Edwards, S, Goh, CL, McCarthy, F, Parker, C, Flohr, P, Paulo, P, Jerónimo, C, Henrique, R, Krause, H, Wach, S, Lieb, V, Rau, TT, Vogel, W, Kuefer, R, Hofer, MD, Perner, S, Rubin, MA, Agarwal, AM, Easton, DF, Amin Al Olama, A, Benlloch, S, Hoegel, J, Stanford, JL, Maier, C & PRACTICAL consortium 2016, 'Prostate cancer risk regions at 8q24 and 17q24 are differentially associated with somatic TMPRSS2:ERG fusion status'  HUMAN MOLECULAR GENETICS , Bd 25, Nr. 24, S. 5490-5499. DOI: 10.1093/hmg/ddw349

Malgorzata-Miller, G, Heinbockel, L, Brandenburg, K, van der Meer, JWM, Netea, MG & Joosten, LAB 2016, 'Bartonella quintana lipopolysaccharide (LPS): structure and characteristics of a potent TLR4 antagonist for in-vitro and in-vivo applications' Scientific Reports, Bd 6, S. 34221. DOI: 10.1038/srep34221

Manrique-Moreno, M, Heinbockel, L, Suwalsky, M, Garidel, P & Brandenburg, K 2016, 'Biophysical study of the non-steroidal anti-inflammatory drugs (NSAID) ibuprofen, naproxen and diclofenac with phosphatidylserine bilayer membranes' Biochimica et biophysica acta, Bd 1858, Nr. 9, S. 2123-31. DOI: 10.1016/j.bbamem.2016.06.009

Martin, L, Peters, C, Heinbockel, L, Moellmann, J, Martincuks, A, Brandenburg, K, Lehrke, M, Müller-Newen, G, Marx, G & Schuerholz, T 2016, 'The synthetic antimicrobial peptide 19-2.5 attenuates mitochondrial dysfunction in cardiomyocytes stimulated with human sepsis serum' INNATE IMMUNITY, Bd 22, Nr. 8, S. 612-619. DOI: 10.1177/1753425916667474

Marwitz, S, Depner, S, Dvornikov, D, Merkle, R, Szczygiel, M, Müller-Decker, K, Lucarelli, P, Wäsch, M, Mairbäurl, H, Rabe, KF, Kugler, C, Vollmer, E, Reck, M, Scheufele, S, Kröger, M, Ammerpohl, O, Siebert, R, Goldmann, T & Klingmüller, U 2016, 'Downregulation of the TGF-β pseudoreceptor BAMBI in non-small cell lung cancer enhances TGF-β signaling and invasion' Cancer Research, Bd 76, Nr. 13, S. 3785-801. DOI: 10.1158/0008-5472.CAN-15-1326

Meder, L, König, K, Ozretić, L, Schultheis, AM, Ueckeroth, F, Ade, CP, Albus, K, Boehm, D, Rommerscheidt-Fuss, U, Florin, A, Buhl, T, Hartmann, W, Wolf, J, Merkelbach-Bruse, S, Eilers, M, Perner, S, Heukamp, LC & Buettner, R 2016, 'NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas' INTERNATIONAL JOURNAL OF CANCER , Bd 138, Nr. 4, S. 927-38. DOI: 10.1002/ijc.29835

Meller, S, VAN Ellen, A, Gevensleben, H, Bicker, A, Hankeln, T, Gorr, TA, Sailer, V, Dröge, F, Schröck, F, Bootz, F, Schröck, A, Perner, S, Dietrich, D & Kristiansen, G 2016, 'Ectopic Myoglobin Expression Is Associated with a Favourable Outcome in Head and Neck Squamous Cell Carcinoma Patients' Anticancer research, Bd 36, Nr. 12, S. 6235-6241. DOI: 10.21873/anticanres.11217

Merz, C, von Mässenhausen, A, Queisser, A, Vogel, W, Andrén, O, Kirfel, J, Duensing, S, Perner, S & Nowak, M 2016, 'IL-6 Overexpression in ERG-Positive Prostate Cancer Is Mediated by Prostaglandin Receptor EP2' AMERICAN JOURNAL OF PATHOLOGY, Bd 186, Nr. 4, S. 974-84. DOI: 10.1016/j.ajpath.2015.12.009

Metzger, E, Willmann, D, McMillan, J, Forne, I, Metzger, P, Gerhardt, S, Petroll, K, von Maessenhausen, A, Urban, S, Schott, A-K, Espejo, A, Eberlin, A, Wohlwend, D, Schüle, KM, Schleicher, M, Perner, S, Bedford, MT, Jung, M, Dengjel, J, Flaig, R, Imhof, A, Einsle, O & Schüle, R 2016, 'Assembly of methylated KDM1A and CHD1 drives androgen receptor-dependent transcription and translocation' Nature structural & molecular biology, Bd 23, Nr. 2, S. 132-139. DOI: 10.1038/nsmb.3153

Nientiedt, M, Deng, M, Schmidt, D, Perner, S, Müller, SC & Ellinger, J 2016, 'Identification of aberrant tRNA-halves expression patterns in clear cell renal cell carcinoma' Scientific Reports, Bd 6, S. 37158. DOI: 10.1038/srep37158

Pfalzgraff, A, Heinbockel, L, Su, Q, Gutsmann, T, Brandenburg, K & Weindl, G 2016, 'Synthetic antimicrobial and LPS-neutralising peptides suppress inflammatory and immune responses in skin cells and promote keratinocyte migration' Scientific Reports, Bd 6, S. 31577. DOI: 10.1038/srep31577

Schnerch, J, Prasse, A, Vlachakis, D, Schuchardt, KL, Pechkovsky, DV, Goldmann, T, Gaede, KI, Müller-Quernheim, J & Zissel, G 2016, 'Functional TLR9 Expression and CXCR3 Ligand Release in Pulmonary Sarcoidosis' AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY , Bd 55, Nr. 5, S. 749-757. DOI: 10.1165/rcmb.2015-0278OC

Schrödter, S, Braun, M, Syring, I, Klümper, N, Deng, M, Schmidt, D, Perner, S, Müller, SC & Ellinger, J 2016, 'Identification of the dopamine transporter SLC6A3 as a biomarker for patients with renal cell carcinoma' LUNG CANCER, Bd 15, Nr. 1, S. 10. DOI: 10.1186/s12943-016-0495-5

Sommer, A, Kordowski, F, Büch, J, Maretzky, T, Evers, A, Andrä, J, Düsterhöft, S, Michalek, M, Lorenzen, I, Somasundaram, P, Tholey, A, Sönnichsen, FD, Kunzelmann, K, Heinbockel, L, Nehls, C, Gutsmann, T, Grötzinger, J, Bhakdi, S & Reiss, K 2016, 'Phosphatidylserine exposure is required for ADAM17 sheddase function' Nature communications, Bd 7, S. 11523. DOI: 10.1038/ncomms11523

Spier, I, Kerick, M, Drichel, D, Horpaopan, S, Altmüller, J, Laner, A, Holzapfel, S, Peters, S, Adam, R, Zhao, B, Becker, T, Lifton, RP, Holinski-Feder, E, Perner, S, Thiele, H, Nöthen, MM, Hoffmann, P, Timmermann, B, Schweiger, MR & Aretz, S 2016, 'Exome sequencing identifies potential novel candidate genes in patients with unexplained colorectal adenomatous polyposis' LUNG CANCER, Bd 15, Nr. 2, S. 281-8. DOI: 10.1007/s10689-016-9870-z

Spier, I, Drichel, D, Kerick, M, Kirfel, J, Horpaopan, S, Laner, A, Holzapfel, S, Peters, S, Adam, R, Zhao, B, Becker, T, Lifton, RP, Perner, S, Hoffmann, P, Kristiansen, G, Timmermann, B, Nöthen, MM, Holinski-Feder, E, Schweiger, MR & Aretz, S 2016, 'Low-level APC mutational mosaicism is the underlying cause in a substantial fraction of unexplained colorectal adenomatous polyposis cases' BMC medical genetics, Bd 53, Nr. 3, S. 172-9. DOI: 10.1136/jmedgenet-2015-103468

Syring, I, Klümper, N, Offermann, A, Braun, M, Deng, M, Boehm, D, Queisser, A, von Mässenhausen, A, Brägelmann, J, Vogel, W, Schmidt, D, Majores, M, Schindler, A, Kristiansen, G, Müller, SC, Ellinger, J, Shaikhibrahim, Z & Perner, S 2016, 'Comprehensive analysis of the transcriptional profile of the Mediator complex across human cancer types' Oncotarget, Bd 7, Nr. 17, S. 23043-55. DOI: 10.18632/oncotarget.8469

Ulmer, AJ, Kaconis, Y, Heinbockel, L, Correa, W, Alexander, C, Rietschel, ET, Mach, J-P, Gorczynski, RM, Heini, A, Rössle, M, Richter, W, Gutsmann, T & Brandenburg, K 2016, 'Enhancing actions of peptides derived from the γ-chain of fetal human hemoglobin on the immunostimulant activities of monophosphoryl lipid A' INNATE IMMUNITY, Bd 22, Nr. 3, S. 168-80. DOI: 10.1177/1753425916632304

von Mässenhausen, A, Deng, M, Billig, H, Queisser, A, Vogel, W, Kristiansen, G, Schröck, A, Bootz, F, Göke, F, Franzen, A, Heasley, L, Kirfel, J, Brägelmann, J & Perner, S 2016, 'Evaluation of FGFR3 as a Therapeutic Target in Head and Neck Squamous Cell Carcinoma' Targeted oncology. DOI: 10.1007/s11523-016-0431-z

von Mässenhausen, A, Sanders, C, Thewes, B, Deng, M, Queisser, A, Vogel, W, Kristiansen, G, Duensing, S, Schröck, A, Bootz, F, Brossart, P, Kirfel, J, Heasley, L, Brägelmann, J & Perner, S 2016, 'MERTK as a novel therapeutic target in head and neck cancer' Oncotarget. DOI: 10.18632/oncotarget.8724

von Mässenhausen, A, Sanders, C, Brägelmann, J, Konantz, M, Queisser, A, Vogel, W, Kristiansen, G, Duensing, S, Schröck, A, Bootz, F, Brossart, P, Kirfel, J, Lengerke, C & Perner, S 2016, 'Targeting DDR2 in Head and Neck Squamous Cell Carcinoma with Dasatinib' INTERNATIONAL JOURNAL OF CANCER . DOI: 10.1002/ijc.30279

von Mässenhausen, A, Brägelmann, J, Billig, H, Thewes, B, Queisser, A, Vogel, W, Kristiansen, G, Schröck, A, Bootz, F, Brossart, P, Kirfel, J & Perner, S 2016, 'Implication of the Receptor Tyrosine Kinase AXL in Head and Neck Cancer Progression' INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , Bd 18, Nr. 1. DOI: 10.3390/ijms18010007

Zhong, Q, Rüschoff, JH, Guo, T, Gabrani, M, Schüffler, PJ, Rechsteiner, M, Liu, Y, Fuchs, TJ, Rupp, NJ, Fankhauser, C, Buhmann, JM, Perner, S, Poyet, C, Blattner, M, Soldini, D, Moch, H, Rubin, MA, Noske, A, Rüschoff, J, Haffner, MC, Jochum, W & Wild, PJ 2016, 'Image-based computational quantification and visualization of genetic alterations and tumour heterogeneity' Scientific Reports, Bd 6, S. 24146. DOI: 10.1038/srep24146


Kriegsmann M, Muley T, Harms A, Tavernar L, Goldmann T, Dienemann H, Herpel E, Warth A. Differential diagnostic value of CD5 and CD117 expression in thoracic tumors: A large scale study of 1465 non-small cell lung cancer cases. Diagn Pathol. 2015 Dec 8;10(1):210. doi: 10.1186/s13000-015-0441-7.

Wagner C, Goldmann T, Rohmann K, Rupp J, Marwitz S, Rotta Detto Loria J, Limmer S, Zabel P, Dalhoff K, Drömann D. Budesonide Inhibits Intracellular Infection with Non-Typeable Haemophilus influenzae despite Its Anti-Inflammatory  Effects in Respiratory Cells and Human Lung Tissue: A Role for p38 MAP Kinase. Respiration. 2015 Nov;90(5):416-25. doi: 10.1159/000439226. Epub 2015 Oct 10.

Goldmann T, Kugler C, Reinmuth N, Vollmer E, Reck M. PD-L1 copy number gain in nonsmall-cell lung cancer defines a new subset of patients for anti PD-L1 therapy. Ann Oncol. 2015 Oct 20. pii: mdv510. [Epub ahead of print]

Martinez de Tejada G, Heinbockel L, Ferrer-Espada R, Heine H, Alexander C, Bárcena-Varela S, Goldmann T, Correa W, Wiesmüller KH, Gisch N, Sánchez-Gómez S, Fukuoka S, Schürholz T, Gutsmann T, Brandenburg K. Lipoproteins/peptides are sepsis-inducing toxins from bacteria that can be neutralized by synthetic anti-endotoxin peptides. Sci Rep. 2015 Sep 22;5:14292. doi: 10.1038/srep14292.

Pedersen F, Marwitz S, Holz O, Kirsten A, Bahmer T, Waschki B, Magnussen H, Rabe KF, Goldmann T, Uddin M, Watz H. Neutrophil extracellular trap formation and extracellular DNA in sputum of stable COPD patients. Respir Med. 2015 Oct;109(10):1360-2. doi: 10.1016/j.rmed.2015.08.008. Epub 2015 Aug 22.

Zehethofer, N, Bermbach, S, Hagner, S, Garn, H, Müller, J, Goldmann, T, Lindner, B, Schwudke, D & König, P 2015, 'Lipid Analysis of Airway Epithelial Cells for Studying Respiratory Diseases' Chromatographia, Bd 78, Nr. 5-6, S. 403-413.

Pedersen, F, Holz, O, Lauer, G, Quintini, G, Kiwull-Schöne, H, Kirsten, A-M, Magnussen, H, Rabe, KF, Goldmann, T & Watz, H 2015, 'Multi-analyte profiling of inflammatory mediators in COPD sputum - The effects of processing' CYTOKINE , Bd 71, Nr. 2, S. 401-4.

Wong, YL, Lautenschläger, I, Dombrowsky, H, Zitta, K, Bein, B, Krause, T, Goldmann, T, Frerichs, I, Steinfath, M, Weiler, N & Albrecht, M 2015, 'Hydroxyethyl Starch (HES 130/0.4) Impairs Intestinal Barrier Integrity and Metabolic Function: Findings from a Mouse Model of the Isolated Perfused Small Intestine' PLOS ONE, Bd 10, Nr. 3, S. e0121497.

Lautenschläger, I, Frerichs, I, Dombrowsky, H, Sarau, J, Goldmann, T, Zitta, K, Albrecht, M, Weiler, N & Uhlig, S 2015, 'Quinidine, but not eicosanoid antagonists or dexamethasone, protect the gut from platelet activating factor-induced vasoconstriction, edema and paralysis' PLOS ONE, Bd 10, Nr. 3, S. e0120802.

Watermann, I, Schmitt, B, Stellmacher, F, Müller, J, Gaber, R, Kugler, C, Reinmuth, N, Huber, RM, Thomas, M, Zabel, P, Rabe, KF, Jonigk, D, Warth, A, Vollmer, E, Reck, M & Goldmann, T 2015, 'Improved diagnostics targeting c-MET in non-small cell lung cancer expression, amplification and activation?' Diagnostic pathology, Bd 10, Nr. 1, S. 130.

Heinbockel, L, Marwitz, S, Barcena Varela, S, Ferrer-Espada, R, Reiling, N, Goldmann, T, Gutsmann, T, Mier, W, Schürholz, T, Drömann, D, Brandenburg, K & Martinez de Tejada, G 2015, 'Therapeutical Administration of Peptide Pep19-2.5 and Ibuprofen Reduces Inflammation and Prevents Lethal Sepsis' PLOS ONE, Bd 10, Nr. 7, S. e0133291.


Shevchuk, O, Abidi, N, Klawonn, F, Wissing, J, Nimtz, M, Kugler, C, Steinert, M, Goldmann, T & Jänsch, L 2014, 'HOPE-Fixation of Lung Tissue Allows Retrospective Proteome and Phosphoproteome Studies' JOURNAL OF PROTEOME RESEARCH , Bd 13, Nr. 11, S. 5230.9.

Gaber, R, Watermann, I, Kugler, C, Reinmuth, N, Huber, RM, Schnabel, PA, Vollmer, E, Reck, M & Goldmann, T 2014, 'Correlation of EGFR expression, gene copy number and clinicopathological status in NSCLC' Diagnostic pathology, Bd 9, Nr. 1, S. 165.

Roessler, FC, Teichert, A, Ohlrich, M, Marxsen, JH, Stellmacher, F, Tanislav, C & Seidel, G 2014, 'Development of a new clot formation protocol for standardized in vitro investigations of sonothrombolysis' JOURNAL OF NEUROSCIENCE METHODS, Bd 237C, S. 26-32.

Reinmuth, N, Heigener, D, Goldmann, T, Watermann, I & Reck, M 2014, 'Reduzierte Dosis von TKI führt nicht zu Wirkungsverlust bei Patienten mit aktivierender EGFR-Mutation' Pneumologie (Stuttgart, Germany), Bd 68, Nr. 9, S. 619-23.

Marwitz, S, Kolarova, J, Reck, M, Reinmuth, N, Kugler, C, Schädlich, I, Haake, A, Zabel, P, Vollmer, E, Siebert, R, Goldmann, T & Ammerpohl, O 2014, 'The tissue is the issue improved methylome analysis from paraffin-embedded tissues by application of the HOPE technique' LABORATORY INVESTIGATION , Bd 94, Nr. 8, S. 927-33.

Bermbach, S, Weinhold, K, Roeder, T, Petersen, F, Kugler, C, Goldmann, T, Rupp, J & König, P 2014, 'Mechanisms of Cilia-Driven Transport in the Airways in the Absence of Mucus' AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY , Bd 51, Nr. 1, S. 56-67.

Lang, DS, Marwitz, S, Heilenkötter, U, Schumm, W, Behrens, O, Simon, R, Reck, M, Vollmer, E & Goldmann, T 2014, 'Transforming Growth Factor-Beta Signaling Leads to uPA/PAI-1 Activation and Metastasis: A Study on Human Breast Cancer Tissues' PATHOLOGY & ONCOLOGY RESEARCH , Bd 20, Nr. 3, S. 727-732.

Lauenstein, L, Switalla, S, Prenzler, F, Seehase, S, Pfennig, O, Förster, C, Fieguth, H-G, Braun, A & Sewald, K 2014, 'Assessment of immunotoxicity induced by chemicals in human precision-cut lung slices (PCLS)' Toxicology In Vitro, Nr. 28(4), S. 588-99.

Petersen, A, Rennert, S, Kull, S, Becker, W-M, Notbohm, H, Goldmann, T & Jappe, U 2014, 'Roasting and lipid binding provide allergenic and proteolytic stability to the peanut allergen Ara h 8' Biological chemistry, Bd 395, Nr. 2, S. 239-50.

Jäger, J, Marwitz, S, Tiefenau, J, Rasch, J, Shevchuk, O, Kugler, C, Goldmann, T & Steinert, M 2014, 'Human lung tissue explants reveal novel interactions during Legionella pneumophila infections' INFECTION AND IMMUNITY , Bd 82, Nr. 1, S. 275-285.

Lang, D, Marwitz, S, Kugler, C, Reinmuth, N, Vollmer, E, Zabel, P, Reck, M & Goldmann, T 2014, 'Double Homeobox Protein DUX 4 in the Human Lung: Expression under Normal and Pathological Conditions' Global Journal of Pathology and Microbiology , Bd 2, DOI:, S. 1-9.


Goldmann T, Vollmer E. Comment on Nietner et al. [Virchows Arch (s2012) 461:259-269]. Virchows Arch. 2013 Jul 20. [Epub ahead of print]

Goldmann T, Pedersen F, Seehase S, Marwitz S, Lang DS, Kirsten AM, Zabel P, Vollmer E, Magnussen H, Rabe KF, Watz H. The Effect of Dithiothreitol on the Transcriptome of Induced Sputum Cells. Respiration. 2013 Apr 9. [Epub ahead of print]

van Bremen T, Drömann D, Luitjens K, Dodt C, Dalhoff K, Goldmann T, Schaaf B.  Triggering receptor expressed on myeloid cells-1 (Trem-1) on blood neutrophils is associated with cytokine inducibility in human E. coli sepsis. Diagn Pathol. 2013 Feb 15;8:24.

Lang DS, Heilenkötter U, Schumm W, Behrens O, Simon R, Vollmer E, Goldmann T.  Optimized immunohistochemistry in combination with image analysis: A reliable alternative to quantitative ELISA determination of uPA and PAI-1 for routine risk group discrimination in breast cancer. Breast. 2013 Oct;22(5):736-43.

Heinbockel L, Sánchez-Gómez S, Martinez de Tejada G, Dömming S, Brandenburg J, Kaconis Y, Hornef M, Dupont A, Marwitz S, Goldmann T, Ernst M, Gutsmann T, Schürholz T, Brandenburg K. Preclinical investigations reveal the broad-spectrum  neutralizing activity of peptide Pep19-2.5 on bacterial pathogenicity factors. Antimicrob Agents Chemother. 2013 Mar;57(3):1480-7.

Pedersen F, Marwitz S, Seehase S, Kirsten AM, Zabel P, Vollmer E, Rabe KF, Magnussen H, Watz H, Goldmann T. HOPE-preservation of paraffin-embedded sputum samples--a new way of bioprofiling in COPD. Respir Med. 2013 Apr;107(4):587-95.

Rotta detto Loria J, Rohmann K, Droemann D, Kujath P, Rupp J, Goldmann T, Dalhoff K.
Nontypeable Haemophilus influenzae activates the NLRP3 inflammasome and leads to caspase-1-dependent secretion of Interleukin-1 - a possible pathway of exacerbations in COPD. 2013 PlosOne 8(6): e66818. Open Access


Fischer A, Schmid B, Ellinghaus D, Nothnagel M, Gaede KI, Schurmann M, Lipinski S, Rosenstiel P, Zissel G, Hohne K, Petrek M, Kolek V, Pabst S, Grohe C, Grunewald J, Ronninger M, Eklund A, Padyukov L, Gieger C, Wichmann H-E, Nebel A, Franke A, Muller-Quernheim J, Hofmann S, Schreiber S. A Novel Sarcoidosis Risk Locus for Europeans on Chromosome 11q13.1. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 2012 Nov;186(9):877–885.

Abdullah M, Goldmann T. Pulmonary haptoglobin (pHp) is part of the surfactant system in the human lung. DIAGNOSTIC PATHOLOGY 2012 Nov;7(1):158. Open Access

Hattar K, Savai R, Subtil FSB, Wilhelm J, Schmall A, Lang DS, Goldmann T, Eul B, Dahlem G, Fink L, Schermuly R-T, Banat G-A, Sibelius U, Grimminger F, Vollmer E, Seeger W, Grandel U. Endotoxin induces proliferation of NSCLC in vitro and in vivo: role of COX-2 and EGFR activation. CANCER IMMUNOLOGY AND IMMUNOTHERAPY 2012 Aug (in press). Open Access

Hofmann S, Fischer A, Nothnagel M, Jacobs G, Schmid B, Wittig M, Franke A, Gaede KI, Schürmann M, Petrek M, Mrazek F, Pabst S, Grohé C, Grunewald J, Ronninger M, Eklund A, Rosenstiel P, Höhne K, Zissel G, Müller-Quernheim J, Schreiber S. Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis. EUROPEAN RESPIRATORY JOURNAL 2012 Aug (in press).

Seidler A, Euler U, Muller-Quernheim J, Gaede KI, Latza U, Groneberg D, Letzel S. Systematic review: progression of beryllium sensitization to chronic beryllium disease. OCCUPATIONAL MEDICINE 2012 Jun;62(7):506–513.

Bang C, Schilhabel A, Weidenbach K, Kopp A, Goldmann T, Gutsmann T, Schmitz RA. Effects of Antimicrobial Peptides on Methanogenic Archaea. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 2012 May;56(8):4123–4130.

On behalf of the Pulmonary Pathology Working Group of the German Society of Pathology, Warth A, Cortis J, Fink L, Fisseler-Eckhoff A, Geddert H, Hager T, Junker K, Kayser G, Kitz J, Länger F, Morresi-Hauf A, Ott G, Petersen I, Stenzinger A, Soltermann A, Ting S, Tischler V, Vollmer E, Schnabel PA, Weichert W. Training increases concordance in classifying pulmonary adenocarcinomas according to the novel IASLC/ATS/ERS classification. VIRCHOWS ARCHIV 2012 Jun;461(2):185–193.

Müller-Fielitz H, Lau M, Jöhren O, Stellmacher F, Schwaninger M, Raasch W. Blood Pressure Response to Angiotensin II is Enhanced in Obese Zucker Rats and is Attributed to an Aldosterone-Dependent Mechanism. BRITISH JOURNAL OF PHARMACOLOGY 2012 Aug;166(8):2417–29.

Goldmann T, Kähler D, Vollmer E. Proteomics? ARCHIVES OF PATHOLOGY AND LABORATORY MEDICINE 2012 Mar;136(3):236–237; author reply 237.

Abdullah M, Kähler D, Vock C, Reiling N, Kugler C, Dromann D, Rupp J, Hauber HP, Fehrenbach H, Zabel P, Vollmer E, Dalhoff K, Goldmann T. Pulmonary haptoglobin and CD163 are functional immunoregulatory elements in the human lung. RESPIRATION 2012 Jan;83(1):61-73.


Hofmann S, Fischer A, Till A, Muller-Quernheim J, Hasler R, Franke A, Gäde KI, Schaarschmidt H, Rosenstiel P, Nebel A, Schurmann M, Nothnagel M, Schreiber S, the GenPhenReSa Consortium. A genome-wide association study reveals evidence of association with sarcoidosis at 6p12.1. EUROPEAN RESPIRATORY JOURNAL 2011 Nov;38(5):1127-1135.

Schultz H, Marwitz S, Baron-Lühr B, Zissel G, Kugler C, Rabe KF, Zabel P, Vollmer E, Gerdes J, Goldmann T. Generation and evaluation of a monoclonal antibody, designated MAdL, as a new specific marker for adenocarcinomas of the lung. BRITISH JORNAL OF CANCER 2011 Aug;105(5):673-81.

Roessler FC, Ohlrich M, Marxsen JH, Stellmacher F, Sprenger A, Dempfle C-E, Seidel G. The platelet-rich plasma clot: a standardized in-vitro clot formation protocol for investigations of sonothrombolysis under physiological flows. BLOOD COAGULATION & FIBRINOLYSIS 2011 Jul;22(5):407-15.

Marwitz S, Abdullah M, Vock C, Fine JS, Visvanathan S, Gaede K, Hauber HP, Zabel P, Goldmann T. HOPE-BAL: Improved Molecular Diagnostics by Application of a Novel Technique for Fixation and Paraffin-Embedding. JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY 2011 Jun;59(6):601-14. Epub 2011 Mar 23.

Andresen E, Lange C, Strodthoff D, Goldmann T, Fischer N, Sahly H, Branscheid D, Heine H. S100A7/psoriasin expression in the human lung: unchanged in patients with COPD, but upregulated upon positive S. aureus detection. BMC PULMONARY MEDICINE 2011;11:10. (Open Access)

Goldmann, T, Neitemeier, H. A definition of time by relation of energy and mass. HYPOTHESIS. 2011;9(1) Available from: (Open Access)

Zweytick D, Deutsch G, Andrä J, Blondelle SE, Vollmer E, Jerala R, Lohner K. Studies on lactoferricin-derived Escherichia coli membrane-active peptides reveal differences in the mechanism of N-acylated versus nonacylated peptides. THE JOURNAL OF BIOLOGICAL CHEMISTRY 2011 Jun;286(24):21266-21276.

Sprenger L, Goldmann T, Vollmer E, Steffen A, Wollenberg B, Zabel P, Hauber H-P. Dexamethasone and N-acetyl-cysteine attenuate Pseudomonas aeruginosa-induced mucus expression in human airways. PULMONARY PHARMACOLOGY & THERAPEUTICS 2011 Apr;24(2):232-239 Epub Dec 2010.

Vollmer E, Goldmann T. Pathology on the edge of interdisciplinarity. A historical epitome. ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY = REVUE ROUMAINE DE MORPHOLOGIE ET EMBRYOLOGIE 2011;52(1 Suppl):223-230.

Andra J, Goldmann T, Ernst CM, Peschel A, Gutsmann T. Multiple peptide resistance factor (MPRF)-mediated resistance of staphylococcus aureus against antimicrobial peptides coincides with a modulated peptide interaction with artificial membranes comprising lysyl-phosphatidylglycerol. JOURNAL OF BIOLOGICAL CHEMISTRY 2011 May 27;286(21):18692-700.

Roessler FC, Ohlrich M, Marxsen JH, Schmieger M, Weber P-K, Stellmacher F, Trillenberg P, Eggers J, Seidel G. Introduction of a new model for time-continuous and non-contact investigations of in-vitro thrombolysis under physiological flow conditions. BMC NEUROLOGY 2011;11:58. (Open Access)

Kayser K, Borkenfeld S, Goldmann T, Kayser G. To be at the right place at the right time. DIAGNOSTIC PATHOLOGY 2011;6:68. (Open Access)

Rohmann K, Tschernig T, Pabst R, Goldmann T, Drömann D. Innate immunity in the human lung: pathogen recognition and lung disease. CELL AND TISSUE RESEARCH 2011 Jan;343(1):167-174.

Abdullah M, Marwitz S, Kähler D, Schultz H, Kugler C, Zabel P, Vollmer E, Goldmann T. Pulmonary haptoglobin: a new marker for adenocarcinomas of the lung? PATHOLOGY 2011 Jan;43(1):70-72.


Müller A, Goldmann T, Seitzer U. Measuring Immune Responses In Situ: Immunofluorescent and Immunoenzymatic Techniques. In: Immunology of Infection (METHODS IN MICROBIOLOGY ; 37). Academic Press; 2010 p. 421-437.

Radtke J, Rezaie SG, Kugler C, Zabel P, Schultz H, Vollmer E, Goldmann T, Lang DS. Expression analysis of EML4 in normal lung tissue and non-small cell lung cancer (NSCLC) in the absence and presence of chemotherapeutics. ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY = REVUE ROUMAINE DE MORPHOLOGIE ET EMBRYOLOGIE 2010;51(4):647-653.

Vollmer E, Schultz H, Stellmacher F, Kähler D, Abdullah M, Galle J, Lang DS, Goldmann T. Tumors in the lung - morphologic features and the challenge of integrating biomarker signatures into diagnostics. ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY = REVUE ROUMAINE DE MORPHOLOGIE ET EMBRYOLOGIE 2010;51(4):607-614.

Orinska Z, Föger N, Huber M, Marschall J, Mirghomizadeh F, Du X, Scheller M, Rosenstiel P, Goldmann T, Bollinger A, Beutler BA, Bulfone-Paus S. I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development. BLOOD 2010 Oct;116(15):2665-2675.

Dromann D, Rupp J, Rohmann K, Osbahr S, Ulmer AJ, Marwitz S, Roschmann K, Abdullah M, Schultz H, Vollmer E, Zabel P, Dalhoff K, Goldmann T. The TGF-beta-Pseudoreceptor BAMBI is strongly expressed in COPD lungs and regulated by nontypeable Haemophilus influenzae. RESPIRATORY RESEARCH 2010 May;11(1):67. Open Access

Hammer MU, Brauser A, Olak C, Brezesinski G, Goldmann T, Gutsmann T, Andrä J. Lipopolysaccharide interaction is decisive for the activity of the antimicrobial peptide NK-2 against Escherichia coli and Proteus mirabilis. BIOCHEMICAL JOURNAL 2010 May;427(3):477-488.

Kahler D, Alexander C, Schultz H, Abdullah M, Branscheid D, Lindner B, Zabel P, Vollmer E, Goldmann T. Proteomics Out of the Archive: Two-dimensional Electrophoresis and Mass Spectrometry Using HOPE-fixed, Paraffin-embedded Tissues. JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY 2010 Mar;58(3):221-228.

Sayk F, Mahnken A, Stellmacher F, Dalhoff K, Merz H. Cancer-to-cancer metastasis: amelanotic melanoma into renal cell carcinoma. DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT 2010 Mar;135(11):507-510.

Lautenschlager I, Dombrowsky H, Frerichs I, Kuchenbecker S, Bade S, Schultz H, Zabel P, Scholz J, Weiler N, Uhlig S. A model of the isolated perfused rat small intestine. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 2010 Feb;298(2):G304-G313.

Schmengler K, Goldmann T, Brade L, Sánchez Carballo PM, Albrecht S, Brade H, Kosma P, Sahly H, Hauber H, Länger F, Meyer R, Welte T, Zähringer U. Monoclonal antibody S60-4-14 reveals diagnostic potential in the identification of Pseudomonas aeruginosa in lung tissues of cystic fibrosis patients. EUROPEAN JOURNAL OF CELL BIOLOGY 2010;89(1):25-33.

Hauber H, Karp D, Goldmann T, Vollmer E, Zabel P. Effect of low tidal volume ventilation on lung function and inflammation in mice. BMC PULMONARY MEDICINE 2010;10(1):21. Open Access

Hauber H, Karp D, Goldmann T, Vollmer E, Zabel P. Comparison of the effect of lps and pam3 on ventilated lungs. BMC PULMONARY MEDICINE 2010;10(1):20. Open Access


Vlastos F, Hillas G, Vidal P, Lacomme S, Galateau-Salle F, Vollmer E, Guzman-Costabel J, Vignaud J, Martinet N. Survey and Biological Insights of Pemetrexed-Related Therapeutic Improvement in Mesothelioma The Nancy Centre of Biological Resources' Mesothelioma Cohort. JOURNAL OF THORACIC ONCOLOGY 2009 Oct;4(10):1259-1263.

Marwitz S, Zeiser T, Schultz H, Kahler D, Abdullah M, Hauber H, Zabel P, Vollmer E, Goldmann T. The human placenta releases substances that drive lung cancer into apoptosis. DIAGNOSTIC PATHOLOGY 2009 Aug;4(1):27. Open Access

Schramm G, Hamilton J, Balog C, Wuhrer M, Gronow A, Beckmann S, Wippersteg V, Grevelding C, Goldmann T, Weber E, Brattig N, Deelder A, Dunne D, Hokke C, Haas H, Doenhoff M. Molecular characterisation of kappa-5, a major antigenic glycoprotein from Schistosoma mansoni eggs. MOLECULAR AND BIOCHEMICAL PARASITOLOGY 2009 Jul;166(1):4-14.

Bohringer H, Lankenau E, Stellmacher F, Reusche E, Huttmann G, Giese A. Imaging of human brain tumor tissue by near-infrared laser coherence tomography. ACTA NEUROCHIRURGICA 2009 May;151(5):507-517.

Schaaf B, Luitjens K, Goldmann T, van Bremen T, Sayk F, Dodt C, Dalhoff K, Droemann D. Mortality in human sepsis is associated with downregulation of Toll-like receptor 2 and CD14 expression on blood monocytes. DIAGNOSTIC PATHOLOGY 2009 Apr;4(1):12. Open Access

Andra J, Hammer M, Grotzinger J, Jakovkin I, Lindner B, Vollmer E, Fedders H, Leippe M, Gutsmann T. Significance of the cyclic structure and of arginine residues for the antibacterial activity of arenicin-1 and its interaction with phospholipid and lipopolysaccharide model membranes. BIOLOGICAL CHEMISTRY 2009 Apr;390(4):337-349.

Goldmann T, Kahler D, Schultz H, Abdullah M, Lang D, Stellmacher F, Vollmer E. On the significance of Surfactant Protein-A within the human lungs. DIAGNOSTIC PATHOLOGY 2009 Mar;4(1):8. Open Access

Kayser K, Schultz H, Goldmann T, Gortler J, Kayser G, Vollmer E. Theory of sampling and its application in tissue based diagnosis. DIAGNOSTIC PATHOLOGY 2009 Feb;4(1):6. Open Access

Knopp U, Knopp A, Stellmacher F, Reusche E, Löning M, Kantelhardt SR, Domarus HV, Arnold H, Giese A. A non-midline spheno-orbital encephalocele in a newborn. CENTRAL EUROPEAN NEUROSURGERY 2009 Feb;70(1):43-47.

Kayser K, Görtler J, Bogovac M, Bogovac A, Goldmann T, Vollmer E, Kayser G. AI (artificial intelligence) in histopathology--from image analysis to automated diagnosis. FOLIA HISTOCHEMICA ET CYTOBIOLOGICA / POLISH ACADEMY OF SCIENCES, POLISH HISTOCHEMICAL AND CYTOCHEMICAL SOCIETY 2009 Jan;47(3):355-361.

Abdullah M, Schultz H, Kahler D, Branscheid D, Dalhoff K, Zabel P, Vollmer E, Goldmann T. Expression of the acute phase protein haptoglobin in human lung cancer and tumor-free lung tissues. PATHOLOGY RESEARCH AND PRACTICE 2009;205(9):639-647.


Kayser K, Hoshang S, Metze K, Goldmann T, Vollmer E, Radziszowski D, Kosjerina Z, Mireskandari M, Kayser G. Texture- and Object-Related Automated Information Analysis in Histological Still Images of Various Organs. ANALYTICAL AND QUANTITATIVE CYTOLOGY AND HISTOLOGY 2008 Dec;30(6):323-335.

Hanuszkiewicz A, Kaczynski Z, Lindner B, Goldmann T, Vollmer E, Debarry J, Heine H, Holst O. Structural Analysis of the Capsular Polysaccharide from Acinetobacter lwoffii F78. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2008 Dec;(36):6183-6188.

Xu F, Droemann D, Rupp J, Shen H, Wu X, Goldmann T, Hippenstiel S, Zabel P, Dalhoff K. Modulation of the Inflammatory Response to Streptococcus pneumoniae in a Model of Acute Lung Tissue Infection. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 2008 Nov;39(5):522-529.

Hauber H, Steffen A, Goldmann T, Vollmer E, Hung H, Wollenberg B, Zabel P. Effect of Steroids, Acetyl-cysteine and Calcium-Activated Chloride Channel Inhibitors on Allergic Mucin Expression in Sinus Mucosa. LARYNGOSCOPE 2008 Sep;118(9):1528-1533.

Schultz H, Kahler D, Branscheid D, Vollmer E, Zabel P, Goldmann T. TKTL1 is overexpressed in a large portion of non-small cell lung cancer specimens. DIAGNOSTIC PATHOLOGY 2008 Aug;3(1):35. Open Access

Vogel K, Blumer N, Korthals M, Mittelstadt J, Garn H, Ege M, von Mutius E, Gatermann S, Bufe A, Goldmann T, Schwaiger K, Renz H, Brandau S, Bauer J, Heine H, Holst O. Animal shed Bacillus licheniformis spores possess allergy-protective as well as inflammatory properties. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 2008 Aug;122(2):307-312.

Kayser K, Gortler J, Goldmann T, Vollmer E, Hufnagl P, Kayser G. Image standards in Tissue-Based Diagnosis (Diagnostic Surgical Pathology). DIAGNOSTIC PATHOLOGY 2008 Apr;3(1):17. Open Access

Goldmann T, Droemann D, Radtke J, Marwitz S, Lang D, Schultz H, Vollmer E. CXCR7 transcription in human non-small cell lung cancer and tumor-free lung tissues; possible regulation upon chemotherapy. VIRCHOWS ARCHIV 2008 Mar;452(3):347-348.

Andra J, Jakovkin I, Grotzinger J, Hecht O, Krasnosdembskaya A, Goldmann T, Gutsmann T, Leippe M. Structure and mode of action of the antimicrobial peptide arenicin. BIOCHEMICAL JOURNAL 2008 Feb;410:113-122.

Esendagli G, Bruderek K, Goldmann T, Busche A, Branscheid D, Vollmer E, Brandau S. Malignant and non-malignant lung tissue areas are differentially populated by natural killer cells and regulatory T cells in non-small cell lung cancer. LUNG CANCER 2008 Jan;59(1):32-40.


Hauber H, Goldmann T, Vollmer E, Wollenberg B, Zabel P. Effect of dexamethasone and ACC on bacteria-induced mucin expression in human airway mucosa. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 2007 Nov;37(5):606-616.

Welker L, Akkan R, Holz O, Schultz H, Magnussen H. Diagnostic outcome of two different CT-guided fine needle biopsy procedures. DIAGNOSTIC PATHOLOGY 2007 Aug;2(1):31. Open Access

Steffan A, Jafari C, Merz H, Galle J, Berger G. Subglottic MALT lymphoma of the larynx - More attention to the glottis. IN VIVO 2007 Aug;21(4):695-698.

Meyer B, Loeschke S, Schultze A, Weigel T, Sandkamp M, Goldmann T, Vollmer E, Bullerdiek J. HMGA2 overexpression in non-small cell lung cancer. MOLECULAR CARCINOGENESIS 2007 Jul;46(7):503-511.

Lin Z, Thomas N, Bibikova M, Seifart C, Wang Y, Guo X, Wang G, Vollmer E, Goldmann T, Garcia E, Zhou L, Fan J, Floros J. DNA methylation markers of surfactant proteins in lung cancer. INTERNATIONAL JOURNAL OF ONCOLOGY 2007 Jul;31(1):181-191.

Lang D, Droemann D, Schultz H, Branscheid D, Martin C, Ressmeyer A, Zabel P, Vollmer E, Goldmann T. A novel human ex vivo model for the analysis of molecular events during lung cancer chemotherapy. RESPIRATORY RESEARCH 2007 Jun;8:43. Open Access

Watz H, Engels K, Loeschke S, Amthor M, Kirsten D, Magnussen H. Lymphangioleiomyomatosis - presence of receptor tyrosine kinases and the angiogenesis factor VEGF-A as potential therapeutic targets. THORAX 2007 Jun;62(6):559-559.

Müller-Quernheim JM, Vollmer E, Galle J. Secondary bronchial botryomycosis due to foreign body aspiration. MONALDI ARCHIVES FOR CHEST DISEASE 2007 Jun;67(2):119-121.

Andra J, Monreal D, de Tejada G, Olak C, Brezesinski G, Gomez S, Goldmann T, Bartels R, Brandenburg K, Moriyon I. Rationale for the design of shortened derivatives of the NK-lysin-derived antimicrobial peptide NK-2 with improved activity against gram-negative pathogens. JOURNAL OF BIOLOGICAL CHEMISTRY 2007 May;282(20):14719-14728.

Droemann D, Rupp J, Goldmann T, Uhlig U, Branscheid D, Vollmer E, Kujath P, Zabel P, Dalhoff K. Disparate innate immune responses to persistent and acute Chlamydia pneumoniae infection in chronic obstructive pulmonary disease. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 2007 Apr;175(8):791-797.

Welker L, Muller M, Holz O, Vollmer E, Magnussen H, Jorres R. Cytological diagnosis of malignant mesothelioma-improvement by additional analysis of hyaluronic acid in pleural effusions. VIRCHOWS ARCHIV 2007 Apr;450(4):455-461.

Kähler, D, Schultz, H, Löschke, S, Branscheid, D, Zabel, P, Vollmer, E, Goldmann, T. Automatisierte Auswertung molekularer Hochdurchsatzanalysen an Tissue Microarrays. FOCUS MUL 2007 Mar;24(1):16-21.

Hauber H, Goldmann T, Vollmer E, Wollenberg B, Hung H, Levitt R, Zabel P. LPS-induced mucin expression in human sinus mucosa can be attenuated by hCLCA inhibitors. JOURNAL OF ENDOTOXIN RESEARCH 2007;13(2):109-116.

2006 (Selection)

Opitz B, Vinzing M, van Laak V, Schmeck B, Heine G, Günther S, Preissner R, Slevogt H, N'Guessan PD, Eitel J, Goldmann T, Flieger A, Suttorp N, Hippenstiel S. Legionella pneumophila induces IFNbeta in lung epithelial cells via IPS-1 and IRF3, which also control bacterial replication. JOURNAL OF BIOLOGICAL CHEMISTRY 2006 Nov;281(47):36173-36179.

Blumenthal A, Ehlers S, Lauber J, Buer J, Lange C, Goldmann T, Heine H, Brandt E, Reiling N. The Wingless homolog, WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation. BLOOD 2006 Aug;108(3):965-973.

Fricke I, Mitchell D, Mittelstadt J, Lehan N, Heine H, Goldmann T, Bohle A, Brandau S. Mycobacteria induce IFN-gamma production in human dendritic cells via triggering of TLR2. JOURNAL OF IMMUNOLOGY 2006 May;176(9):5173-5182.

Prasse A, Pechkovsky D, Toews G, Jungraithmayr W, Kollert F, Goldmann T, Vollmer E, Muller-Quernheim J, Zissel G. A vicious circle of alveolar macrophages and fibroblasts perpetuates pulmonary fibrosis via CCL18. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 2006 Apr;173(7):781-792.

Hillemann D, Galle J, Vollmer E, Richter E. Real-time PCR assay for improved detection of Mycobacterium tuberculosis complex in paraffin-embedded tissues. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE 2006 Mar;10(3):340-342.

Droeman D, Rupp J, Goldmann T, Kujath P, Vollmer E, Zabel P, Dalhoff K. In vitro Infektion im humanen Lungengewebsmodell am Beispiel von Chlamydia pneumoniae. FOCUS MUL 2006 Mar;23(1):24-27.

Bibikova M, Lin Z, Zhou L, Chudin E, Garcia E, Wu B, Doucet D, Thomas N, Wang Y, Vollmer E, Goldmann T, Seifart C, Jiang W, Barker D, Chee M, Floros J, Fan J. High-throughput DNA methylation profiling using universal bead arrays. GENOME RESEARCH 2006 Mar;16(3):383-393. Open Access

Busche A, Goldmann T, Naumann U, Steinle A, Brandau S. Natural killer cell-mediated rejection of experimental human lung cancer by genetic overexpression of major histocompatibility complex class I chain-related gene A. HUMAN GENE THERAPY 2006 Feb;17(2):135-146.

Vollmer E, Galle J, Lang DS, Loeschke S, Schultz H, Goldmann T. The HOPE technique opens up a multitude of new possibilities in pathology. ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY = REVUE ROUMAINE DE MORPHOLOGIE ET EMBRYOLOGIE 2006;47(1):15-19.

Goldmann T, Burgemeister R, Sauer U, Loeschke S, Lang D, Branscheid D, Zabel P, Vollmer E. Enhanced molecular analyses by combination of the HOPE-technique and laser microdissection. DIAGNOSTIC PATHOLOGY 2006;1(2). DOI: 10.1186/1746-1596-1-2 Open Access

2005 (Selection)

Droemann D, Goldmann T, Tiedje T, Zabel P, Dalhoff K, Schaaf B. Toll-like receptor 2 expression is decreased on alveolar macrophages in cigarette smokers and COPD patients [Internet]. RESPIRATORY RESEARCH 2005 Jul;6(68). DOI: 10.1186/1465-9921-6-68 Open Access

Kayser K, Kosjerina Z, Goldmann T, Gian K, Kazmierczak B, Vollmer E. Lung carcinoma-associated atypical adenomatoid hyperplasia, squamous cell dysplasia, and chromosome alterations in non-neoplastic bronchial mucosa. LUNG CANCER 2005 Feb;47(2):205-214.

Droemann D, Albrecht D, Gerdes J, Ulmer A, Branscheid D, Vollmer E, Dalhoff K, Zabel P, Goldmann T. Human lung cancer cells express functionally active Toll-like receptor 9 [Internet]. RESPIRATORY RESEARCH 2005 Jan;6(1). DOI: 10.1186/1465-9921-6-1 Open Access

Loeschke S, Goldmann T, Vollmer E. Improved detection of mycobacterial DNA by PCR in formalin-fixed, paraffin-embedded tissues using thin sections. PATHOLOGY RESEARCH AND PRACTICE 2005;201(1):37-40.

Kayser K, Kosjerina Z, Goldmann T, Kayser G, Kazmierczak B, Vollmer E. Phenotype and genotype associations of lung carcinoma with atypical adenomatoid hyperplasia, squamous cell dysplasia, and chromosome alterations in non-neoplastic bronchial mucosa. ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY = REVUE ROUMAINE DE MORPHOLOGIE ET EMBRYOLOGIE 2005;46(1):5-10.

Goldmann T, Dromann D, Marzouki M, Schimmel U, Debel K, Branscheid D, Zeiser T, Rupp J, Gerdes J, Zabel P, Vollmer E. Tissue microarrays from HOPE-fixed specimens allow for enhanced high throughput molecular analyses in paraffin-embedded material. PATHOLOGY RESEARCH AND PRACTICE 2005;201(8-9):599-602.

2004 (Selection)

Rupp J, Droemann D, Goldmann T, Zabel P, Solbach W, Vollmer E, Branscheid D, Dalhoff K, Maass M. Alveolar epithelial cells type II are major target cells for C. pneumoniae in chronic but not in acute respiratory infection. FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY 2004 Jul;41(3):197-203.

Goldmann T, Flohr AM, Murua Escobar H, Gerstmayer B, Janssen U, Bosio A, Loeschke S, Vollmer E, Bullerdiek J. The HOPE-technique permits Northern blot and microarray analyses in paraffin-embedded tissues. PATHOLOGY RESEARCH AND PRACTICE 2004;200(7-8):511-515.