Forschungszentrum Borstel
Forschungszentrum Borstel

Scientific Publications 2006

Publications 2006

PEER-REVIEWED ARTICLES

Aly S, Wagner K, Keller C, Malm S, Malzan A, Brandau S, Bange FC, Ehlers S. Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice. J Pathol 2006; 210(3):298-305.

Andrä J, Rademann J, Howe J, Koch MH, Heine H, Zähringer U, Brandenburg K. Endotoxin-like properties of a rhamnolipid exotoxin from Burkholderia (Pseudomonas) plantarii – immune cell stimulation and biophysical characterization. Biol Chem 2006; 387:301-310.

Bauer J, Brandenburg K, Zähringer U, Rademann R. Chemical synthesis of a glycolipid library by a solid phase strategy allows to elucidate the structural specificity of immune stimulation by rhamnolipids. Chem Eur J 2006; 12:7116-7124.

Bekeredjian-Ding I, Inamura S, Giese T, Moll H, Endres S, Sing A, Zähringer U, Hartmann G, Staphylococcus aureus triggers T cell-independent B cell proliferation through the engagement of the B cell receptor and Toll-like receptor 2. J Immunol. In press.

Bibikova M, Lin Z, Zhou L, Chudin E, Garcia EW, Wu B, Doucet D, Thomas NJ, Wang Y, Vollmer E, Goldmann T, Seifart C, Jiang W, Barker DL, Chee MS, Floros J, Fan JB. High-throughput DNA methylation profiling using universal bead arrays. Genome Res. 2006; 16(9):1075-83.

Blumenthal A, Ehlers A, Lauber J, Buer J, Lange C, Goldmann T, Heine H, Gerdes J, Kemler R, Brandt E, Reiling N. The Wingless homologue Wnt5a and its receptor Frizzled-5 regulate cytokine production in human mononuclear cells in response to microbial stimuli. Blood 2006; 108 (3):965-973.

Böhling A, Hagge SO, Roes S, Podschun R, Sahly H, Harder J, Schröder JM, Grotzinger J, Seydel U, Gutsmann T. Lipid-specific membrane activity of human beta-defensin-3. Biochemistry 2006; 45:5663-5670.

Bongiorni S, Pasqualini B, Taranta M, Singh PB, Prantera G. Epigenetic regulation of facultative heterochromatinisation via the Me(3)K9H3/HP1/Me(3)K20H4 pathway. J Cell Sci. In press.

Bruhn H, Winkelmann J, Andersen C, Andrä J, Leippe M. Dissection of the mechanisms of cytolytic and antibacterial activity of lysenin, a defence protein of the annelid Eisenia fetida. Dev Comp Immunol 2006; 30:597-606.

Bullwinkel J, Baron-Luhr B, Ludemann A, Wohlenberg C, Gerdes J, Scholzen T. Ki-67 protein is associated with ribosomal RNA transcription in quiescent and proliferating cells. J Cell Physiol 2006; 206(3):624-35.

Busche A, Goldmann T, Naumann U, Steinle A, Brandau S. Natural killer cell-mediated rejection of experimental human lung cancer by genetic overexpression of major histocompatibility complex class I chain-related gene a. Hum Gene Ther. 2006;17(2):135-46.

Bystrova OV, Knirel YA, Lindner B, Kocharova NA, Kondakova AN, Zähringer U, Pier GB. Structures of the core oligosaccharide and O-units in the R- and SR-type lipopolysaccharides of reference strains of Pseudomonas aeruginosa O-serogroups. FEMS Immunol Med Microbiol 2006; 46:85-99.

Csernok E, Ai M, Gross WL, Wicklein D, Petersen A, Lindner B, Lamprecht P, Holle JU, Hellmich B. Wegener autoantigen induces maturation of dendritic cells and licenses them for Th1 priming via the protease-activated receptor-2 pathway. Blood 2006; 107:4440-4448.

De Castro C, Caranannte A, Lanzetta R, Lindner B, Nunziata R, Parrilli M, Holst O. Structural characterisation of the core oligosaccharides isolated from the lipooligosaccharide fraction of Agrobacterium tumefaciens A1. Chem Eur J 2006; 12:4668-4674.

Dennison SR, Dante S, Hauss T, Brandenburg K, Harris F, Phoenix DA. Deuteration can affect the conformational behaviour of amphiphilic alpha-helical structures. Biophys Chem 2006; 9: 115-120.

Dennison SR, Howe J, Morton LH, Brandenburg K, Harris F, Phoenix DA. Interactions of an anionic antimicrobial peptide with Staphylococcus aureus membranes. Biochem Biophys Res Commun 2006; 347:1006-1010.

Dennison SR, Morton L, Brandenburg K, Harris F, Phoenix D. Investigations into the ability of an oblique alpha-helical template to provide the basis for design of an antimicobial amphiphilic peptide. FEBS J 2006; 273:3792-3803.

Dialynas GK, Makatsori D, Kourmouli N, Theodoropoulos PA, McLean K, Terjung S, Singh PB, Georgatos SD. Methylation-independent binding to histone H3 and cell cycle-dependent incorporation of HP1beta into heterochromatin. J Biol Chem 2006; 281(20):14350-60.

Diel R, Ernst M, Döscher G, Visuri-Karbe L, Greinert U, Niemann S, Nienhaus A, Lange C. Circumventing the effect of BCG-vaccination in detecting MTB infection with a new blood test. Eur Respir J 2006; 28:16-23.

Diel R, Nienhaus A, Lange C, Meywald-Walther K, Forßbohm M, Schaberg T. Tuberculosis contact investigation with a new specific blood test in a low-incidence population containing a high proportion of BCG-vaccinated persons. Resp Res 2006; 7:77.

Diel R, Nienhaus A, Lange C, Schaberg T. Cost optimisation of screening for latent tuberculosis in close contacts. Eur Respir J 2006; 28: 35-44.

Dittrich D, Keller C, Ehlers S, Schultz JE, Sander P. Characterization of a Mycobacterium tuberculosis mutant deficient in pH-sensing adenylate cyclase Rv1264. Int J Med Microbiol 2006; 296(8):563-6.

Dolinay T, Kaminski N, Felgendreher M, Kim HP, Reynolds P, Watkins SC, Karp D, Uhlig S, Choi AMK. 2006. Gene expression profiling of target genes in ventilator-induced lung injury. Physiol Genomics 26: 68-75.

Drieschner N, Belge G, Rippe V, Meiboom M, Loeschke S, Bullerdiek J.Evidence for a 3p25 breakpoint hot spot region in thyroid tumors of follicular origin. Thyroid 2006; 16:1091-6.

Eder W, Klimecki, Yu L, von Mutius E, Riedler J, Braun-Fahrländer C, Nowak D, Holst O, Martinez FD, ALEX Study Team. Association between exposure to farming, allergies and genetic variation in CARD4/NOD1. Allergy 2006; 61:1117-1124.

Erpenbeck VJ, Ziegert M, Cavalet-Blanco D, Martin C, Baelder R, Glaab T, Braun A, Steinhilber W, Luettig B, Uhlig S, Hoymann HG, Krug N, Hohlfeld JM. Surfactant protein D inhibits early airway response in Aspergillus fumigatus-sensitized mice. Clin Exp Allergy 2006; 36: 940-40.

Fabretti F, Theilacker C, Baldassarri L, Kaczynski Z, Kropec A, Holst O, Huebner J. Alanine esters of enterococcal lipoteichoic acid play a role in biofilm formation and resistance to antimicrobial peptides. Infect Immun 2006; 74:4164-4171.

Fantner GE, Oroudjev E, Schitter G, Golde LS, Thurner PJ, Finch MM, Thurner P, Gutsmann T, Morse DE, Hansma H, Hansma PK. Sacrificial Bonds and Hidden Length: Unraveling Molecular Mesostructures in Tough Materials. Biophys J 2006; 90:1411-1418.

Fricke I, Mitchell D, Mittelstädt J, Lehan N, Heine H, Goldmann T, Böhle A, Brandau S.Mycobacteria induce IFN-g production in human dendritic cells via triggering of toll-like receptor 2. J Immunol 2006; 176(9):5173-82.

Fritz M, Lokstein H, Hackenberg D, Welti R, Roth M, Zähringer U, Fulda M, Hellmeyer W, Ott C, Wolter FP, Heinz E. Channeling of eukaryotic diacylglycerol into the biosynthesis of plastidial hosphatidylglycerol. J Biol Chem, Dec 11; [Epub ahead of print], PMID: 17158889.

Gangloff SC, Laqdam G, Dupray V, Fukase K, Brandenburg K, Guenounou M, Schaaf P, Voegel JC, Jessel N. Biologically active lipid A antagonist embedded in a multilayered polyelectrolyte architecture. Biomaterials 2006; 27:1771-1777.

Gilleron M, Lindner B, Puzo, G. MS/MS approach for characterization of the fatty acid distribution on mycobacterial phosphatidyl-myo-inositol-mannosides Anal Chem 2006; 78:8543-8548.

Goldmann T, Burgemeister R, Sauer U, Loeschke S, Lang DS, Branscheid D, Zabel P, Vollmer E. Enhanced molecular analyses by combination of the HOPE-technique and laser microdissection. Diagnostic Patho 2006, 1:2.

Gorczynski RM, Alexander C, Bessler W, Brandenburg K, Fournier K, Hoffmann P, Mach JP, Mueller S, Rietschel ET, Terzioglu E, Ulmer AJ, Waelli T, Zähringer U, Khatri I. Role of MIF and glutathione, in association with fetal ovine globin chain (Hbgamma) and LPS, in induction of TNFal. Immunol Letters 2006; 105:140-149.

Hagge SO, Hammer MU, Wiese A, Seydel U, Gutsmann T. Calcium adsorption and displacement: Characterization of lipid monolayers and their interaction with membrane-active peptides/proteins. BMC Biochem 2006; 7:15.

Heine H, Gronow S, Zamyatina A, Kosma P, Brade H. Biological activities of synthetic Chlamydia Lipid A. J Endotoxin Res. In press.

Heinzelmann F, Jendrossek V, Lauber K, Nowak K, Eldh T, Boras R, Handrick R, Henkel M, Martin C, Uhlig S, Kohler D, Eltzschig HK, Wehrmann M, Budach W, Belka C. Irradiation-induced pneumonitis mediated by the CD95/CD95-ligand system. J Natl Canc Inst 2006; 98: 1248-1251.

Hillemann D, Galle J, Vollmer E, Richter E. Real-time PCR assay for improved detection of Mycobacterium tuberculosis complex in paraffin-embedded tissues. Int J Tuberc Lung Dis 2006; 10(3):340-2.

Hoffmann C, Ernst M, Meyer P, Wolf E, Rosenkranz T, Plettenberg A, Stoehr A, Horst HA, Marienfeld K, Lange C. Evolving characteristics of toxoplasmosis in HIV-1-infected patients: Clinical course and Toxoplasma gondii-specific immune responses, CMI 2006. In press.

Hölscher C, Arendse B, Schwegmann A, Myburgh E, Brombacher F. Impairment of alternative macrophage activation delays cutaneous leishmaniasis in non-healing BALB/c mice. J Immunol 2006; 176:1115-1121.

Hölzl G, Witt S, Kelly AA, Zähringer U, Warnecke D, Dörmann P, Heinz E. Functional differences between galactolipids and glucolipids. Revealed in photosynthesis of higher plants. Proc Natl Acad Sci USA. 2006; 103:7512-7517.

Howe J, Bauer J, Andrä J, Schromm AB, Ernst M, Rössle M, Zähringer U, Rademann J, Brandenburg K. Biophysical characterization of synthetic rhamnolipids. FEBS J 2006; 273: 5101-12.

Howe J, Hammer M, Alexander C, Rössle M, Fournier K, Mach J-P, Waelli T, Gorczynski RM, Ulmer AJ, Zähringer U, Rietschel E Th, Brandenburg K. Biophysical Characterization of the Interaction of Endotoxins with Hemoglobins, Medicinal Chem 2006; 3:20-31.

Inamura S, Fujimoto Y, Kawasaki A, Shiokawa Z, Woelk E, Heine H, Lindner B, Inohara N, Kusumoto S, Fukase K. Synthesis of peptidoglycan fragments and evaluation of their biological activity. Org Biomol Chem 2006; 4:232-242.

Jafari C, Ernst M, Diel R, Greinert U, Scheuerer B, Kirsten D, Marienfeld K, Lalvani A, Lange C. Rapid diagnosis of smear negative tuberculosis by bronchoalveolar-lavage enzyme-linked immunospot. AJRCCM 2006; 174: 1048-54.

Jin J, Zeng H, Schmid KW, Toetsch M, Uhlig S, Möröy T. The zinc finger protein gfi1 acts upstream of TNF to attenuate endotoxin-mediated inflammatory response in the lung. Eur J Immunol 2006; 36: 421-430.

Ju JS, Cho MH, Brade L, Kim JH, Park JW, Ha NC et al. A novel 40-kDa protein containing six repeats of an epidermal growth factor-like domain functions as a pattern recognition protein for lipopolysaccharide. J Immunol 2006; 177(3):1838-1845.

Kaczynski Z, Karapetyan G, Evidente A, Iacobellis NS, Holst O. The structure of a putative exopolysaccharide of Burkholderia gladioli pv. agaricicola. Carbohydr Res 2006; 341:285-288.

Karagiannidisa C, Hense G, Martin C, Epstein M, Rückert B, Mantel PY, Menz G, Uhlig S, Blaser K, Schmidt-Weber CB. Overlapping functions but differential expression of activin A and TGF-β in asthma. J Allergy Clin Invest 2006; 117: 111-118.

Karapetyan G, Kaczynski Z, Evidente A, Iacobellis NS, Holst O. The structure of the O-specific polysaccharide of the lipopolysaccharide from Burkholderia gladioli pv. agaricicola. Carbohydr Res 2006; 341:930-934.

Kasper B, Brandt E, Ernst M, Petersen F. Neutrophil adhesion to endothelial cells induced by platelet factor 4 requires sequential activation of Ras, Syk, and JNK MAP kinases. Blood 2006; 107:1768-1775.

Keller C, Hoffmann R, Lang R, Brandau S, Hermann C, Ehlers S. Genetically determined susceptibility to tuberculosis in mice causally involves accelerated and enhanced recruitment of granulocytes. Infect Immun 2006; 74(7):4295-309.

Komarova B, Tsvetkov YE, Knirel YA, Zähringer U, Pier GB, Nifantiev NE. Synthesis of a common trisaccharide fragment of glycoforms of the outer core region of the Pseudomonas aeruginosa lypopolysaccharide. Highly stereoselective α glucosylation assisted by remote participation. Tetrahedron Lett 2006; 47:3583–3587.

Lange C, Schaberg T, Diel R, Greinert U. Aktueller Stand der Tuberkulosediagnostik. Dtsch Med Wochenschr 2006; 131:341-47.

Lebrun AH, Wunder C, Hildebrand J, Churin J, Zähringer U, Lindner B, Meyer TF, Heinz E, Warnecke D. Cloning of a Cholesterol-α-Glucosyltransferase from Helicobacter pylori. J Biol Chem 2006; 281:17765-17772.

Leone S, Molinaro A, Lindner B, Romano I, Nicolaus B, Parrilli M, Lanzetta R, Holst O. The structures of glycolipids isolated from the highly thermophilic bacterium Thermus thermophilus Samu-SA1. Glycobiol 2006; 16:766-775.

Meredith TC, Aggarwal P, Mamat U, Lindner B, Woodard RW. Redefining the requisite lipopolysaccharide structure in Escherichia coli. ACS Chem Biol 2006; 1:33-42.

Meyer B, Loeschke S, Schulze A, Weigel T, Sandham M, Goldmann T, Vollmer E, Bullerdiek J. HMGA2 overexpression in non small cell lung cancer. Mol Carcinogenesis. In press.

Mueller M, Stamme C, Draing C, Hartung T, Seydel U, Schromm AB. Cell activation of human macrophages by lipoteichoic acid is strongly attenuated by lipopolysaccharide-binding protein (LBP). J Biol Chem 2006; 281: 31448-56.

Muller-Loennies S, Gronow S, Brade L, MacKenzie R, Kosma P, Brade H. A monoclonal antibody against a carbohydrate epitope in lipopolysaccharide differentiates Chlamydophila psittaci from Chlamydophila pecorum, Chlamydophila pneumoniae, and Chlamydia trachomatis. Glycobiology 2006; 16(3):184-196.

Opitz B, Vinzing M, van Laak V, Schmeck B, Heine G, Gunther S, Preissner R, Slevogt H, N Guessan PD, Eitel J, Goldmann T, Flieger A, Suttorp N, Hippenstiel S. Legionella pneumophila induced IFNbeta in lung epithelial cells via IPS-1 and IRF3 which also control bacterial replication. J Biol Chem. 2006 Sep 19; [Epub ahead of print].

Papavlassopoulos M, Stamme C, Thon L, Adam D, Hillemann D, Seydel U, Schromm AB. MaxiK-blockade selectively inhibits the LPS-induced IB-NF-B signaling pathway in macrophages. J Immunol 2006; 177: 4086-4093.

Pechkovsky DV, Goldmann T, Vollmer E, Muller-Quernheim J, Zissel G. Interleukin-18 expression by alveolar epithelial cells type II in tuberculosisand sarcoidosis. FEMS Immunol Med Microbiol. 2006; 46(1):30-8.

Perlovich GL, Strakhova NN, Kazachenko VP, Volkova TV, Tkachev VV, Schaper K-J, Raevsky OA. Studying thermodynamic aspects of sublimation, solubility and solvation processes and crystal structure analysis of some sulfonamides. Int J Pharm 2006 Oct 28 [Epub ahead of print]. In press.

Perlovich GL, Tkachev VV, Schaper K-J, Raevsky OA. N-(2-Chlorophenyl)benzenesulfonamide. Acta Cryst 2006; E62:780-782.

Perlovich GL, Tkachev VV, Schaper K-J, Raevsky OA. N-(4-Chlorophenyl)benzenesulfonamide. Acta Cryst 2006; E62:376-378.

Perlovich GL, Tkachev VV, Schaper K-J, Strakhova NN. 4-Amino-N-(2,3-dichlorophenyl)benzenesulfonamide. Acta Cryst 2006; E62:5634-5636.

Peters M, Kauth M, Schwarze J, Körner-Rettberg C, Riedler J, Nowak D, Braun-Fahrländer C, von Mutius E, Bufe A, Holst O, ALEX Study Group. Inhalation of stable-dust extracts prevents airway inflammation and hyperresponsiveness in a mouse model of allergic asthma. Thorax 2006; 61:134-139.

Petersen A, Suck R, Lindner B, Georgieva D, Ernst M, Notbohm H, Wicklein D, Cromwell O, Becker WM. Phl p 3: structural and immunological characterization of a major allergen of timothy grass pollen. Clin Exp Allergy 2006; 36:840-849.

Prasse A, Pechkovsky DV, Toews GB, Jungraithmayr W, Kollert F, Goldmann T, Vollmer E, Muller-Quernheim J, Zissel G. A Vicious Circle of Alveolar Macrophages and Fibroblasts Perpetuates Pulmonary Fibrosis via CCL18. Am J Respir Crit Care Med 2006; 173:781-792.

Raevsky OA, Grigor’ev VJ, Raevskaja OE, Schaper K-J. Physicochemical properties / descriptors governing the solubility and partitioning in water-solvent-gas systems. Part 1. Partitioning between octanol and air. SAR & QSAR Environ Res 2006; 17:285-297.

Rahmanzadeh R, Hüttmann G, Gerdes J, Scholzen T. Chromophore-assisted light inactivation (CALI) of pKi-67 leads to Inhibition of ribosomal RNA-Synthesis. Cell Proliferation. In press.

Rausch A, Hessmann M, Hölscher A, Schreiber T, Bulfone-Paus S, Ehlers, Hölscher C. Interleukin-15 mediates protection against experimental tuberculosis: A role for NKG2D-dependent effector mechanisms of CD8+ T cells. Eur J Immunol 2006; 36:1156-1167.

Ressmeyer AR, Larsson AK, Vollmer E, Dahlen SE, Uhlig S, Martin C. Characterization of guinea pig precision-cut lung slices. Eur Respir J 2006; 28: 603-611.

Roes S, Mumm F, Seydel U, Gutsmann T. Localization of the lipopolysaccharide-binding protein (LBP) in phospholipid membranes by atomic force microscopy. J Biol Chem 2006; 281:2757-2763.

Rückerl D, Hessmann M, Yoshimoto T, Ehlers S, Hölscher C. Alternatively activated macrophages express the IL-27 receptor alpha chain WSX-1. Immunbiology 2006; 211:427-436.

Runza VL, Hehlgans T, Echtenacher B, Zähringer U, Schwaeble WJ, Männel DN. Localization of the mouse defense lectin ficolin B in lysosomes of activated macrophages. J Endotox Res 2006; 12:120-126.

Sausbier M, Zhou XB, Beier B, Sausbier U, Wolpers D, Maget S, Martin C, Dietrich A, Ressmeyer AR, Renz H, Schlossmann J, Hofmann F, Neuhuber W, Gudermann T, Uhlig S, Korth M, Ruth P. Reduced rather than enhanced cholinergic airway constriction in mice with ablation of the large conductance Ca2+-activated K+ channel. FASEB J. In press.

Saxena AK, Schaper K-J. QSAR analysis of the time and dose dependent anti-inflammatory in vivo activity of substituted imidazo[1,2-a]pyridines using Artificial Neural Networks. QSAR Comb Sci 2006; 25:590-597.

Scheel O, Papavlassopoulos M, Blunck R, Gebert R, Hartung T, Zähringer U, Seydel U, Schromm AB. Cell activation by ligands of the TLR/IL-1 receptor family depends on MaxiK channel function in human macrophages. Infect Immun 2006; 74:4354-4356.

Scheuerer B, van Mark A, Zabel P. Diagnostic impact of the bronchoalveolar lavage, Ergomed 2006; 2: 38-46.

Schiemann F, Grimm TA, Hoch J, Gross R, Lindner B, Petersen F, Bulfone-Paus S, Brandt E. Mast cells and neutrophils proteolytically activate chemokine precursor CTAP-III and are subject to counter-regulation by PF4 through inhibition of chymase and cathepsin G. Blood 2006; 107:2234-2242.

Schramm G, Gronow A, Knobloch J, Wippersteg V, Grevelding CG, Galle J, Fuller H, Stanley RG, Chiodini PL, Haas H, Doenhoff MJ. IPSE/alpha-1: a major immunogenic component secreted from Schistosoma mansoni eggs. Mol Biochem Parasitol 2006; 147(1):9-19.

Schreiber T*, Ehlers S*, Aly S, Hölscher A, Hartmann S, Lipp M, Lowe JB, Hölscher C. Selectin ligand-independent priming and maintenance of T cell immunity during airborne tuberculosis. J Immunol 2006; 176:1131-40. *TS and SE contributed equally.

Siddiqui RA, Hoischen C, Holst O, Heinze I, Schlott B, Gumpert J, Diekmann S, Grosse F, Platzer M. The analysis of cell division and cell wall synthesis genes reveals mutationally inactivated ftsQ and mraY in a protoplast-type L-form of Escherichia coli. FEMS Lett 2006; 258:305-311.

Srivastava M, Meinders A, Steinwede K, Maus R, Lucke N, Buhling F, Ehlers S, Welte T, Maus U A. Mediator responses of alveolar macrophages and kinetics of mononuclear phagocyte subset recruitment during acute primary and secondary mycobacterial infections in the lungs of mice. Cell Microbiol 2006 Oct 18; Epub. In press.

Taylor AM, Holst O, Thomas-Oates JE. Mass spectrometric profiling of O-linked glycans released directly from glycoproteins in gels using in-gel reductive β-elimination. Proteomics 2006; 6:2936-2946.

Theilacker C, Kaczynski Z, Kropec A, Fabretti F, Sange T, Holst O, Huebner J. Opsonic antibodies to Enterococcus faecalis 12030 are directed against lipoteichoic acid. Infect Immun 2006; 74:5703-5712.

Tkachev VV, Schaper K-J, Strakhova NN, Kazachenko VP. N-(2,3-Dichlorophenyl)benzenesulfonamide. Acta Cryst 2006; E62:2514-2515.

Trujillo-Vargas CM, Werner-Klein M, Wohlleben G, Polte T, Hansen G, Ehlers S, Erb KJ. Helminth derived products inhibit the development of allergic responses in mice. Am J Respir Crit Care Med 2006 Nov 22; Epub. In press.

Uhlig U, Drömann D, Goldmann T, Dombrowsky H, Vollmer E, Zabel P, Uhlig S. Pulmonary responses to overventilation in late multiple organ failure. Anesthesiology 2006; 105: 1192-1200.

van Zandbergen G, Bollinger A, Wenzel A, Kamhawi S, Voll R, Klinger M, Müller A, Hölscher C, Herrmann M, Sacks D, Solbach W, Laskay T. Leishmania disease development depends on the presence of apoptotic promastigotes in the virulent inoculum. Proc Natl Acad Sci USA 2006; 103:13837-12842.

Vinogradov EV, Lindner B, Seltmann G, Radziejewska-Lebrecht J, Holst O. Lipopolysaccharides from Serratia marcescens possess one or two 4-amino-4-deoxy-L-arabinopyranose 1-phosphate residues in the lipid A and D-glycero-D-talo-oct-2-ulopyranosonic acid in the inner core region. Chem Eur J 2006; 12:6692-6700.

Visser L, Melief MJ, van Riel D, van Meurs M, Sick EA, Inamura S, Bajramovic JJ, Amor S, Hintzen RQ, Boven LA, 't Hart BA, Laman JD. Phagocytes containing a disease-promoting Toll-like receptor/Nod ligand are present in the brain during demyelinating disease in primates. Am J Pathol 2006; 169:1671-1685.

Vollmer E, Galle J, Lang DS, Loeschke S, Schultz H, Goldmann T. The HOPE Technique Opens Up a Multitude of New Possibilities in Pathology. Rom J Morphol Embryol 2006; 47(1):15-9.

Weyhers H, Ehlers S, Hahn H, Souto EB, Muller RH. Solid lipid nanoparticles (SLN)-effects of lipid composition on in vitro degradation and in vivo toxicity. Pharmazie 2006; 61(6):539-44.

Wiedemann I, Böttiger T, Bonelli RR, Wiese A, Hagge SO, Gutsmann T, Seydel U, Deegan L, Hill C, Ross P, Sahl HG. The mode of action of the lantibiotic lacticin 3147 - a complex mechanism involving specific interaction of two peptides and the cell wall precursor lipid II. Mol Microbiol. 2006; 61:285-296.

Winkler S, Reimann-Berg N, Murua Escobar H, Loeschke S, Eberle N, Hoinghaus R, Nolte I, Bullerdiek J. Polysomy 13 in a canine prostate carcinoma underlining its significance in the development of prostate cancer. Cancer Genet Cytogenet 2006; 169:154-8.

Wu R, Singh PB, Gilbert DM. Uncoupling global and fine-tuning replication timing determinants for mouse pericentric heterochromatin. J Cell Biol 2006; 174(2):185-94.

Wunder C, Churin Y, Winau F, Warnecke D, Vieth M, Lindner B, Zähringer U, Heinz E, Meyer TF. Sugar turns benefit of cholesterol into immune evasion in microbial infection. Nature Medicine 2006; 12:1030-1038.

Zacharowski K, Zacharowski P, Koch A, Baban A, Trana N, Berkels R, Papewalis C, Schulze-Osthoff K, Knuefermann P, Zähringer U, Schumann RR, Rettori V, McCann SM, Bornstein SR. Toll-like receptor 4 plays a crucial role in the immune–adrenal response to systemic inflammatory response syndrome. Proc Natl Acad Sci USA 2006; 103:6392-6397.

Zweytick D, Pabst G, Abuja PM, Jilek A, Blondelle SE, Andrä J, Jerala R, Monreal D, Martinez de Tejada G, Lohner K. Influence of N-acylation of a peptide derived from human lactoferricin on membrane selectivity. Biochim. Biophys. Acta 2006; 1758:1426-1435.

Reviews and Book Chapters

Andrä J, Gutsmann T, Garidel P, Brandenburg K. Mechanisms of endotoxin neutralization by synthetic cationic compounds. J Endotox Res 2006; 12:261-277.

Brandenburg K, Garidel P, Howe J, Andrä J, Hawkins L, Koch MHJ, Seydel U. What can calorimetry tell us about three-dimensional aggregate structures of phospho- and glycolipids? Thermochim. Acta 2006; 445:133-143.
Hölscher C. Aptamers against interleukin-12-related cytokines as novel therapeutics in autoimmune diseases. Expert Opinion Ther Patents 2006; 16:1025-1030.

Lange C, Lederman MM. Infections Involving Bones and Joints. In: Cecil´s Essentials of medicine 7th (Eds. Andreoli TE, Carpenter CJ, Loscalzo J, Griggs RC) Elsevier. In press.

Lange C, Lederman MM. Infections of the Head and Neck. In: Cecil´s Essentials of medicine 7th (Eds. Andreoli TE, Carpenter CJ, Loscalzo J, Griggs RC) Elsevier. In press.

Lange C, Lederman MM. Infections of the Lower Respiratory Tract. In: Cecil´s Essentials of medicine 7th (Eds. Andreoli TE, Carpenter CJ, Loscalzo J, Griggs RC) Elsevier. In press.

Lange C, Lederman MM. Infections of the Urinary Tract. In: Cecil´s Essentials of medicine 7th (Eds. Andreoli TE, Carpenter CJ, Loscalzo J, Griggs RC) Elsevier. In press.

Lange C, Lederman MM. Infectious Diarrhea. In: Cecil´s Essentials of medicine 7th (Eds. Andreoli TE, Carpenter CJ, Loscalzo J, Griggs RC) Elsevier. In press.
Lange C, Lederman MM. Intra-Abdominal Abscess and Peritonitis. In: Cecil´s Essentials of medicine 7th (Eds. Andreoli TE, Carpenter CJ, Loscalzo J, Griggs RC) Elsevier. In press

Lange C, Lederman MM. Skin and Soft Tissue Infections. In: Cecil´s Essentials of medicine 7th (Eds. Andreoli TE, Carpenter CJ, Loscalzo J, Griggs RC) Elsevier. In press.

Lange CG, Schieferstein C, Toossi Z. Tuberculosis. In: HIVMEDICINE 2006 (eds. Hoffmann C, Kamps BS) Steinhäuser Verlag Wuppertal, pp 422 -435.

Müller-Loennies S, Di Padova F, Brade L, Brade H, Rietschel E Th. Anti-endotoxin antibodies - a cross-reactive and cross-protective monoclonal antibody against a conserved epitope of Escherichia coli and Salmonella enterica. In: Engelmann L, Schuster H-P, editors. Diagnostik und Intensivtherapie bei Sepsis und Multiorganversagen. Darmstadt: Steinkopff, 2006: 163-174.

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