Medizin

Klin. u. Exp. Pathologie

Publikationen

2014

Marwitz S, Kolarova J, Reck M, Reinmuth N, Kugler C, Schädlich I, Haake A, Zabel P, Vollmer E, Siebert R, Goldmann T, Ammerpohl O. The tissue is the issue: improved methylome analysis from paraffin-embedded tissues by application of the HOPE technique. Lab Invest. 2014 Jun 16. doi: 10.1038/labinvest.2014.79. [Epub ahead of print]

Lang DS, Marwitz S, Heilenkötter U, Schumm W, Behrens O, Simon R, Reck M, Vollmer E, Goldmann T. Transforming Growth Factor-Beta signaling leads to uPA/PAI-1 activation and metastasis: A study on human breast cancer tissues. Pathol Oncol Res. 2014 Mar 9. [Epub ahead of print]

Jäger, J, Marwitz, S, Tiefenau, J, Rasch, J, Shevchuk, O, Kugler, C, Goldmann, T & Steinert, M 2014, 'Human lung tissue explants reveal novel interactions during Legionella pneumophila infections' Infection and immunity, Bd 82, Nr. 1, S. 275-285., dx.doi.org/10.1128/IAI.00703-13

2013

Goldmann T, Vollmer E. Comment on Nietner et al. [Virchows Arch (s2012) 461:259-269]. Virchows Arch. 2013 Jul 20. [Epub ahead of print]

Goldmann T, Pedersen F, Seehase S, Marwitz S, Lang DS, Kirsten AM, Zabel P, Vollmer E, Magnussen H, Rabe KF, Watz H. The Effect of Dithiothreitol on the Transcriptome of Induced Sputum Cells. Respiration. 2013 Apr 9. [Epub ahead of print]

van Bremen T, Drömann D, Luitjens K, Dodt C, Dalhoff K, Goldmann T, Schaaf B.  Triggering receptor expressed on myeloid cells-1 (Trem-1) on blood neutrophils is associated with cytokine inducibility in human E. coli sepsis. Diagn Pathol. 2013 Feb 15;8:24.

Lang DS, Heilenkötter U, Schumm W, Behrens O, Simon R, Vollmer E, Goldmann T.  Optimized immunohistochemistry in combination with image analysis: A reliable alternative to quantitative ELISA determination of uPA and PAI-1 for routine risk group discrimination in breast cancer. Breast. 2013 Oct;22(5):736-43.

Heinbockel L, Sánchez-Gómez S, Martinez de Tejada G, Dömming S, Brandenburg J, Kaconis Y, Hornef M, Dupont A, Marwitz S, Goldmann T, Ernst M, Gutsmann T, Schürholz T, Brandenburg K. Preclinical investigations reveal the broad-spectrum  neutralizing activity of peptide Pep19-2.5 on bacterial pathogenicity factors. Antimicrob Agents Chemother. 2013 Mar;57(3):1480-7.

Pedersen F, Marwitz S, Seehase S, Kirsten AM, Zabel P, Vollmer E, Rabe KF, Magnussen H, Watz H, Goldmann T. HOPE-preservation of paraffin-embedded sputum samples--a new way of bioprofiling in COPD. Respir Med. 2013 Apr;107(4):587-95.

Rotta detto Loria J, Rohmann K, Droemann D, Kujath P, Rupp J, Goldmann T, Dalhoff K.
Nontypeable Haemophilus influenzae activates the NLRP3 inflammasome and leads to caspase-1-dependent secretion of Interleukin-1 - a possible pathway of exacerbations in COPD. 2013 PlosOne 8(6): e66818. Open Access

2012

Fischer A, Schmid B, Ellinghaus D, Nothnagel M, Gaede KI, Schurmann M, Lipinski S, Rosenstiel P, Zissel G, Hohne K, Petrek M, Kolek V, Pabst S, Grohe C, Grunewald J, Ronninger M, Eklund A, Padyukov L, Gieger C, Wichmann H-E, Nebel A, Franke A, Muller-Quernheim J, Hofmann S, Schreiber S. A Novel Sarcoidosis Risk Locus for Europeans on Chromosome 11q13.1. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 2012 Nov;186(9):877–885.

Abdullah M, Goldmann T. Pulmonary haptoglobin (pHp) is part of the surfactant system in the human lung. DIAGNOSTIC PATHOLOGY 2012 Nov;7(1):158. Open Access

Hattar K, Savai R, Subtil FSB, Wilhelm J, Schmall A, Lang DS, Goldmann T, Eul B, Dahlem G, Fink L, Schermuly R-T, Banat G-A, Sibelius U, Grimminger F, Vollmer E, Seeger W, Grandel U. Endotoxin induces proliferation of NSCLC in vitro and in vivo: role of COX-2 and EGFR activation. CANCER IMMUNOLOGY AND IMMUNOTHERAPY 2012 Aug (in press). Open Access

Hofmann S, Fischer A, Nothnagel M, Jacobs G, Schmid B, Wittig M, Franke A, Gaede KI, Schürmann M, Petrek M, Mrazek F, Pabst S, Grohé C, Grunewald J, Ronninger M, Eklund A, Rosenstiel P, Höhne K, Zissel G, Müller-Quernheim J, Schreiber S. Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis. EUROPEAN RESPIRATORY JOURNAL 2012 Aug (in press).

Seidler A, Euler U, Muller-Quernheim J, Gaede KI, Latza U, Groneberg D, Letzel S. Systematic review: progression of beryllium sensitization to chronic beryllium disease. OCCUPATIONAL MEDICINE 2012 Jun;62(7):506–513.

Bang C, Schilhabel A, Weidenbach K, Kopp A, Goldmann T, Gutsmann T, Schmitz RA. Effects of Antimicrobial Peptides on Methanogenic Archaea. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 2012 May;56(8):4123–4130.

On behalf of the Pulmonary Pathology Working Group of the German Society of Pathology, Warth A, Cortis J, Fink L, Fisseler-Eckhoff A, Geddert H, Hager T, Junker K, Kayser G, Kitz J, Länger F, Morresi-Hauf A, Ott G, Petersen I, Stenzinger A, Soltermann A, Ting S, Tischler V, Vollmer E, Schnabel PA, Weichert W. Training increases concordance in classifying pulmonary adenocarcinomas according to the novel IASLC/ATS/ERS classification. VIRCHOWS ARCHIV 2012 Jun;461(2):185–193.

Müller-Fielitz H, Lau M, Jöhren O, Stellmacher F, Schwaninger M, Raasch W. Blood Pressure Response to Angiotensin II is Enhanced in Obese Zucker Rats and is Attributed to an Aldosterone-Dependent Mechanism. BRITISH JOURNAL OF PHARMACOLOGY 2012 Aug;166(8):2417–29.

Goldmann T, Kähler D, Vollmer E. Proteomics? ARCHIVES OF PATHOLOGY AND LABORATORY MEDICINE 2012 Mar;136(3):236–237; author reply 237.

Abdullah M, Kähler D, Vock C, Reiling N, Kugler C, Dromann D, Rupp J, Hauber HP, Fehrenbach H, Zabel P, Vollmer E, Dalhoff K, Goldmann T. Pulmonary haptoglobin and CD163 are functional immunoregulatory elements in the human lung. RESPIRATION 2012 Jan;83(1):61-73.

2011

Hofmann S, Fischer A, Till A, Muller-Quernheim J, Hasler R, Franke A, Gäde KI, Schaarschmidt H, Rosenstiel P, Nebel A, Schurmann M, Nothnagel M, Schreiber S, the GenPhenReSa Consortium. A genome-wide association study reveals evidence of association with sarcoidosis at 6p12.1. EUROPEAN RESPIRATORY JOURNAL 2011 Nov;38(5):1127-1135.

Schultz H, Marwitz S, Baron-Lühr B, Zissel G, Kugler C, Rabe KF, Zabel P, Vollmer E, Gerdes J, Goldmann T. Generation and evaluation of a monoclonal antibody, designated MAdL, as a new specific marker for adenocarcinomas of the lung. BRITISH JORNAL OF CANCER 2011 Aug;105(5):673-81.

Roessler FC, Ohlrich M, Marxsen JH, Stellmacher F, Sprenger A, Dempfle C-E, Seidel G. The platelet-rich plasma clot: a standardized in-vitro clot formation protocol for investigations of sonothrombolysis under physiological flows. BLOOD COAGULATION & FIBRINOLYSIS 2011 Jul;22(5):407-15.

Marwitz S, Abdullah M, Vock C, Fine JS, Visvanathan S, Gaede K, Hauber HP, Zabel P, Goldmann T. HOPE-BAL: Improved Molecular Diagnostics by Application of a Novel Technique for Fixation and Paraffin-Embedding. JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY 2011 Jun;59(6):601-14. Epub 2011 Mar 23.

Andresen E, Lange C, Strodthoff D, Goldmann T, Fischer N, Sahly H, Branscheid D, Heine H. S100A7/psoriasin expression in the human lung: unchanged in patients with COPD, but upregulated upon positive S. aureus detection. BMC PULMONARY MEDICINE 2011;11:10. (Open Access)

Goldmann, T, Neitemeier, H. A definition of time by relation of energy and mass. HYPOTHESIS. 2011;9(1) Available from: http://hypothesisjournal.com/index.php/main/article/view/199 (Open Access)

Zweytick D, Deutsch G, Andrä J, Blondelle SE, Vollmer E, Jerala R, Lohner K. Studies on lactoferricin-derived Escherichia coli membrane-active peptides reveal differences in the mechanism of N-acylated versus nonacylated peptides. THE JOURNAL OF BIOLOGICAL CHEMISTRY 2011 Jun;286(24):21266-21276.

Sprenger L, Goldmann T, Vollmer E, Steffen A, Wollenberg B, Zabel P, Hauber H-P. Dexamethasone and N-acetyl-cysteine attenuate Pseudomonas aeruginosa-induced mucus expression in human airways. PULMONARY PHARMACOLOGY & THERAPEUTICS 2011 Apr;24(2):232-239 Epub Dec 2010.

Vollmer E, Goldmann T. Pathology on the edge of interdisciplinarity. A historical epitome. ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY = REVUE ROUMAINE DE MORPHOLOGIE ET EMBRYOLOGIE 2011;52(1 Suppl):223-230.

Andra J, Goldmann T, Ernst CM, Peschel A, Gutsmann T. Multiple peptide resistance factor (MPRF)-mediated resistance of staphylococcus aureus against antimicrobial peptides coincides with a modulated peptide interaction with artificial membranes comprising lysyl-phosphatidylglycerol. JOURNAL OF BIOLOGICAL CHEMISTRY 2011 May 27;286(21):18692-700.

Roessler FC, Ohlrich M, Marxsen JH, Schmieger M, Weber P-K, Stellmacher F, Trillenberg P, Eggers J, Seidel G. Introduction of a new model for time-continuous and non-contact investigations of in-vitro thrombolysis under physiological flow conditions. BMC NEUROLOGY 2011;11:58. (Open Access)

Kayser K, Borkenfeld S, Goldmann T, Kayser G. To be at the right place at the right time. DIAGNOSTIC PATHOLOGY 2011;6:68. (Open Access)

Rohmann K, Tschernig T, Pabst R, Goldmann T, Drömann D. Innate immunity in the human lung: pathogen recognition and lung disease. CELL AND TISSUE RESEARCH 2011 Jan;343(1):167-174.

Abdullah M, Marwitz S, Kähler D, Schultz H, Kugler C, Zabel P, Vollmer E, Goldmann T. Pulmonary haptoglobin: a new marker for adenocarcinomas of the lung? PATHOLOGY 2011 Jan;43(1):70-72.

2010

Müller A, Goldmann T, Seitzer U. Measuring Immune Responses In Situ: Immunofluorescent and Immunoenzymatic Techniques. In: Immunology of Infection (METHODS IN MICROBIOLOGY ; 37). Academic Press; 2010 p. 421-437.

Radtke J, Rezaie SG, Kugler C, Zabel P, Schultz H, Vollmer E, Goldmann T, Lang DS. Expression analysis of EML4 in normal lung tissue and non-small cell lung cancer (NSCLC) in the absence and presence of chemotherapeutics. ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY = REVUE ROUMAINE DE MORPHOLOGIE ET EMBRYOLOGIE 2010;51(4):647-653.

Vollmer E, Schultz H, Stellmacher F, Kähler D, Abdullah M, Galle J, Lang DS, Goldmann T. Tumors in the lung - morphologic features and the challenge of integrating biomarker signatures into diagnostics. ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY = REVUE ROUMAINE DE MORPHOLOGIE ET EMBRYOLOGIE 2010;51(4):607-614.

Orinska Z, Föger N, Huber M, Marschall J, Mirghomizadeh F, Du X, Scheller M, Rosenstiel P, Goldmann T, Bollinger A, Beutler BA, Bulfone-Paus S. I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development. BLOOD 2010 Oct;116(15):2665-2675.

Dromann D, Rupp J, Rohmann K, Osbahr S, Ulmer AJ, Marwitz S, Roschmann K, Abdullah M, Schultz H, Vollmer E, Zabel P, Dalhoff K, Goldmann T. The TGF-beta-Pseudoreceptor BAMBI is strongly expressed in COPD lungs and regulated by nontypeable Haemophilus influenzae. RESPIRATORY RESEARCH 2010 May;11(1):67. Open Access

Hammer MU, Brauser A, Olak C, Brezesinski G, Goldmann T, Gutsmann T, Andrä J. Lipopolysaccharide interaction is decisive for the activity of the antimicrobial peptide NK-2 against Escherichia coli and Proteus mirabilis. BIOCHEMICAL JOURNAL 2010 May;427(3):477-488.

Kahler D, Alexander C, Schultz H, Abdullah M, Branscheid D, Lindner B, Zabel P, Vollmer E, Goldmann T. Proteomics Out of the Archive: Two-dimensional Electrophoresis and Mass Spectrometry Using HOPE-fixed, Paraffin-embedded Tissues. JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY 2010 Mar;58(3):221-228.

Sayk F, Mahnken A, Stellmacher F, Dalhoff K, Merz H. Cancer-to-cancer metastasis: amelanotic melanoma into renal cell carcinoma. DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT 2010 Mar;135(11):507-510.

Lautenschlager I, Dombrowsky H, Frerichs I, Kuchenbecker S, Bade S, Schultz H, Zabel P, Scholz J, Weiler N, Uhlig S. A model of the isolated perfused rat small intestine. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 2010 Feb;298(2):G304-G313.

Schmengler K, Goldmann T, Brade L, Sánchez Carballo PM, Albrecht S, Brade H, Kosma P, Sahly H, Hauber H, Länger F, Meyer R, Welte T, Zähringer U. Monoclonal antibody S60-4-14 reveals diagnostic potential in the identification of Pseudomonas aeruginosa in lung tissues of cystic fibrosis patients. EUROPEAN JOURNAL OF CELL BIOLOGY 2010;89(1):25-33.

Hauber H, Karp D, Goldmann T, Vollmer E, Zabel P. Effect of low tidal volume ventilation on lung function and inflammation in mice. BMC PULMONARY MEDICINE 2010;10(1):21. Open Access

Hauber H, Karp D, Goldmann T, Vollmer E, Zabel P. Comparison of the effect of lps and pam3 on ventilated lungs. BMC PULMONARY MEDICINE 2010;10(1):20. Open Access

2009

Vlastos F, Hillas G, Vidal P, Lacomme S, Galateau-Salle F, Vollmer E, Guzman-Costabel J, Vignaud J, Martinet N. Survey and Biological Insights of Pemetrexed-Related Therapeutic Improvement in Mesothelioma The Nancy Centre of Biological Resources' Mesothelioma Cohort. JOURNAL OF THORACIC ONCOLOGY 2009 Oct;4(10):1259-1263.

Marwitz S, Zeiser T, Schultz H, Kahler D, Abdullah M, Hauber H, Zabel P, Vollmer E, Goldmann T. The human placenta releases substances that drive lung cancer into apoptosis. DIAGNOSTIC PATHOLOGY 2009 Aug;4(1):27. Open Access

Schramm G, Hamilton J, Balog C, Wuhrer M, Gronow A, Beckmann S, Wippersteg V, Grevelding C, Goldmann T, Weber E, Brattig N, Deelder A, Dunne D, Hokke C, Haas H, Doenhoff M. Molecular characterisation of kappa-5, a major antigenic glycoprotein from Schistosoma mansoni eggs. MOLECULAR AND BIOCHEMICAL PARASITOLOGY 2009 Jul;166(1):4-14.

Bohringer H, Lankenau E, Stellmacher F, Reusche E, Huttmann G, Giese A. Imaging of human brain tumor tissue by near-infrared laser coherence tomography. ACTA NEUROCHIRURGICA 2009 May;151(5):507-517.

Schaaf B, Luitjens K, Goldmann T, van Bremen T, Sayk F, Dodt C, Dalhoff K, Droemann D. Mortality in human sepsis is associated with downregulation of Toll-like receptor 2 and CD14 expression on blood monocytes. DIAGNOSTIC PATHOLOGY 2009 Apr;4(1):12. Open Access

Andra J, Hammer M, Grotzinger J, Jakovkin I, Lindner B, Vollmer E, Fedders H, Leippe M, Gutsmann T. Significance of the cyclic structure and of arginine residues for the antibacterial activity of arenicin-1 and its interaction with phospholipid and lipopolysaccharide model membranes. BIOLOGICAL CHEMISTRY 2009 Apr;390(4):337-349.

Goldmann T, Kahler D, Schultz H, Abdullah M, Lang D, Stellmacher F, Vollmer E. On the significance of Surfactant Protein-A within the human lungs. DIAGNOSTIC PATHOLOGY 2009 Mar;4(1):8. Open Access

Kayser K, Schultz H, Goldmann T, Gortler J, Kayser G, Vollmer E. Theory of sampling and its application in tissue based diagnosis. DIAGNOSTIC PATHOLOGY 2009 Feb;4(1):6. Open Access

Knopp U, Knopp A, Stellmacher F, Reusche E, Löning M, Kantelhardt SR, Domarus HV, Arnold H, Giese A. A non-midline spheno-orbital encephalocele in a newborn. CENTRAL EUROPEAN NEUROSURGERY 2009 Feb;70(1):43-47.

Kayser K, Görtler J, Bogovac M, Bogovac A, Goldmann T, Vollmer E, Kayser G. AI (artificial intelligence) in histopathology--from image analysis to automated diagnosis. FOLIA HISTOCHEMICA ET CYTOBIOLOGICA / POLISH ACADEMY OF SCIENCES, POLISH HISTOCHEMICAL AND CYTOCHEMICAL SOCIETY 2009 Jan;47(3):355-361.

Abdullah M, Schultz H, Kahler D, Branscheid D, Dalhoff K, Zabel P, Vollmer E, Goldmann T. Expression of the acute phase protein haptoglobin in human lung cancer and tumor-free lung tissues. PATHOLOGY RESEARCH AND PRACTICE 2009;205(9):639-647.

2008

Kayser K, Hoshang S, Metze K, Goldmann T, Vollmer E, Radziszowski D, Kosjerina Z, Mireskandari M, Kayser G. Texture- and Object-Related Automated Information Analysis in Histological Still Images of Various Organs. ANALYTICAL AND QUANTITATIVE CYTOLOGY AND HISTOLOGY 2008 Dec;30(6):323-335.

Hanuszkiewicz A, Kaczynski Z, Lindner B, Goldmann T, Vollmer E, Debarry J, Heine H, Holst O. Structural Analysis of the Capsular Polysaccharide from Acinetobacter lwoffii F78. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2008 Dec;(36):6183-6188.

Xu F, Droemann D, Rupp J, Shen H, Wu X, Goldmann T, Hippenstiel S, Zabel P, Dalhoff K. Modulation of the Inflammatory Response to Streptococcus pneumoniae in a Model of Acute Lung Tissue Infection. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 2008 Nov;39(5):522-529.

Hauber H, Steffen A, Goldmann T, Vollmer E, Hung H, Wollenberg B, Zabel P. Effect of Steroids, Acetyl-cysteine and Calcium-Activated Chloride Channel Inhibitors on Allergic Mucin Expression in Sinus Mucosa. LARYNGOSCOPE 2008 Sep;118(9):1528-1533.

Schultz H, Kahler D, Branscheid D, Vollmer E, Zabel P, Goldmann T. TKTL1 is overexpressed in a large portion of non-small cell lung cancer specimens. DIAGNOSTIC PATHOLOGY 2008 Aug;3(1):35. Open Access

Vogel K, Blumer N, Korthals M, Mittelstadt J, Garn H, Ege M, von Mutius E, Gatermann S, Bufe A, Goldmann T, Schwaiger K, Renz H, Brandau S, Bauer J, Heine H, Holst O. Animal shed Bacillus licheniformis spores possess allergy-protective as well as inflammatory properties. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 2008 Aug;122(2):307-312.

Kayser K, Gortler J, Goldmann T, Vollmer E, Hufnagl P, Kayser G. Image standards in Tissue-Based Diagnosis (Diagnostic Surgical Pathology). DIAGNOSTIC PATHOLOGY 2008 Apr;3(1):17. Open Access

Goldmann T, Droemann D, Radtke J, Marwitz S, Lang D, Schultz H, Vollmer E. CXCR7 transcription in human non-small cell lung cancer and tumor-free lung tissues; possible regulation upon chemotherapy. VIRCHOWS ARCHIV 2008 Mar;452(3):347-348.

Andra J, Jakovkin I, Grotzinger J, Hecht O, Krasnosdembskaya A, Goldmann T, Gutsmann T, Leippe M. Structure and mode of action of the antimicrobial peptide arenicin. BIOCHEMICAL JOURNAL 2008 Feb;410:113-122.

Esendagli G, Bruderek K, Goldmann T, Busche A, Branscheid D, Vollmer E, Brandau S. Malignant and non-malignant lung tissue areas are differentially populated by natural killer cells and regulatory T cells in non-small cell lung cancer. LUNG CANCER 2008 Jan;59(1):32-40.

2007

Hauber H, Goldmann T, Vollmer E, Wollenberg B, Zabel P. Effect of dexamethasone and ACC on bacteria-induced mucin expression in human airway mucosa. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 2007 Nov;37(5):606-616.

Welker L, Akkan R, Holz O, Schultz H, Magnussen H. Diagnostic outcome of two different CT-guided fine needle biopsy procedures. DIAGNOSTIC PATHOLOGY 2007 Aug;2(1):31. Open Access

Steffan A, Jafari C, Merz H, Galle J, Berger G. Subglottic MALT lymphoma of the larynx - More attention to the glottis. IN VIVO 2007 Aug;21(4):695-698.

Meyer B, Loeschke S, Schultze A, Weigel T, Sandkamp M, Goldmann T, Vollmer E, Bullerdiek J. HMGA2 overexpression in non-small cell lung cancer. MOLECULAR CARCINOGENESIS 2007 Jul;46(7):503-511.

Lin Z, Thomas N, Bibikova M, Seifart C, Wang Y, Guo X, Wang G, Vollmer E, Goldmann T, Garcia E, Zhou L, Fan J, Floros J. DNA methylation markers of surfactant proteins in lung cancer. INTERNATIONAL JOURNAL OF ONCOLOGY 2007 Jul;31(1):181-191.

Lang D, Droemann D, Schultz H, Branscheid D, Martin C, Ressmeyer A, Zabel P, Vollmer E, Goldmann T. A novel human ex vivo model for the analysis of molecular events during lung cancer chemotherapy. RESPIRATORY RESEARCH 2007 Jun;8:43. Open Access

Watz H, Engels K, Loeschke S, Amthor M, Kirsten D, Magnussen H. Lymphangioleiomyomatosis - presence of receptor tyrosine kinases and the angiogenesis factor VEGF-A as potential therapeutic targets. THORAX 2007 Jun;62(6):559-559.

Müller-Quernheim JM, Vollmer E, Galle J. Secondary bronchial botryomycosis due to foreign body aspiration. MONALDI ARCHIVES FOR CHEST DISEASE 2007 Jun;67(2):119-121.

Andra J, Monreal D, de Tejada G, Olak C, Brezesinski G, Gomez S, Goldmann T, Bartels R, Brandenburg K, Moriyon I. Rationale for the design of shortened derivatives of the NK-lysin-derived antimicrobial peptide NK-2 with improved activity against gram-negative pathogens. JOURNAL OF BIOLOGICAL CHEMISTRY 2007 May;282(20):14719-14728.

Droemann D, Rupp J, Goldmann T, Uhlig U, Branscheid D, Vollmer E, Kujath P, Zabel P, Dalhoff K. Disparate innate immune responses to persistent and acute Chlamydia pneumoniae infection in chronic obstructive pulmonary disease. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 2007 Apr;175(8):791-797.

Welker L, Muller M, Holz O, Vollmer E, Magnussen H, Jorres R. Cytological diagnosis of malignant mesothelioma-improvement by additional analysis of hyaluronic acid in pleural effusions. VIRCHOWS ARCHIV 2007 Apr;450(4):455-461.

Kähler, D, Schultz, H, Löschke, S, Branscheid, D, Zabel, P, Vollmer, E, Goldmann, T. Automatisierte Auswertung molekularer Hochdurchsatzanalysen an Tissue Microarrays. FOCUS MUL 2007 Mar;24(1):16-21.

Hauber H, Goldmann T, Vollmer E, Wollenberg B, Hung H, Levitt R, Zabel P. LPS-induced mucin expression in human sinus mucosa can be attenuated by hCLCA inhibitors. JOURNAL OF ENDOTOXIN RESEARCH 2007;13(2):109-116.

2006 (Selection)

Opitz B, Vinzing M, van Laak V, Schmeck B, Heine G, Günther S, Preissner R, Slevogt H, N'Guessan PD, Eitel J, Goldmann T, Flieger A, Suttorp N, Hippenstiel S. Legionella pneumophila induces IFNbeta in lung epithelial cells via IPS-1 and IRF3, which also control bacterial replication. JOURNAL OF BIOLOGICAL CHEMISTRY 2006 Nov;281(47):36173-36179.

Blumenthal A, Ehlers S, Lauber J, Buer J, Lange C, Goldmann T, Heine H, Brandt E, Reiling N. The Wingless homolog, WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation. BLOOD 2006 Aug;108(3):965-973.

Fricke I, Mitchell D, Mittelstadt J, Lehan N, Heine H, Goldmann T, Bohle A, Brandau S. Mycobacteria induce IFN-gamma production in human dendritic cells via triggering of TLR2. JOURNAL OF IMMUNOLOGY 2006 May;176(9):5173-5182.

Prasse A, Pechkovsky D, Toews G, Jungraithmayr W, Kollert F, Goldmann T, Vollmer E, Muller-Quernheim J, Zissel G. A vicious circle of alveolar macrophages and fibroblasts perpetuates pulmonary fibrosis via CCL18. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 2006 Apr;173(7):781-792.

Hillemann D, Galle J, Vollmer E, Richter E. Real-time PCR assay for improved detection of Mycobacterium tuberculosis complex in paraffin-embedded tissues. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE 2006 Mar;10(3):340-342.

Droeman D, Rupp J, Goldmann T, Kujath P, Vollmer E, Zabel P, Dalhoff K. In vitro Infektion im humanen Lungengewebsmodell am Beispiel von Chlamydia pneumoniae. FOCUS MUL 2006 Mar;23(1):24-27.

Bibikova M, Lin Z, Zhou L, Chudin E, Garcia E, Wu B, Doucet D, Thomas N, Wang Y, Vollmer E, Goldmann T, Seifart C, Jiang W, Barker D, Chee M, Floros J, Fan J. High-throughput DNA methylation profiling using universal bead arrays. GENOME RESEARCH 2006 Mar;16(3):383-393. Open Access

Busche A, Goldmann T, Naumann U, Steinle A, Brandau S. Natural killer cell-mediated rejection of experimental human lung cancer by genetic overexpression of major histocompatibility complex class I chain-related gene A. HUMAN GENE THERAPY 2006 Feb;17(2):135-146.

Vollmer E, Galle J, Lang DS, Loeschke S, Schultz H, Goldmann T. The HOPE technique opens up a multitude of new possibilities in pathology. ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY = REVUE ROUMAINE DE MORPHOLOGIE ET EMBRYOLOGIE 2006;47(1):15-19.

Goldmann T, Burgemeister R, Sauer U, Loeschke S, Lang D, Branscheid D, Zabel P, Vollmer E. Enhanced molecular analyses by combination of the HOPE-technique and laser microdissection. DIAGNOSTIC PATHOLOGY 2006;1(2). DOI: 10.1186/1746-1596-1-2 Open Access

2005 (Selection)

Droemann D, Goldmann T, Tiedje T, Zabel P, Dalhoff K, Schaaf B. Toll-like receptor 2 expression is decreased on alveolar macrophages in cigarette smokers and COPD patients [Internet]. RESPIRATORY RESEARCH 2005 Jul;6(68). DOI: 10.1186/1465-9921-6-68 Open Access

Kayser K, Kosjerina Z, Goldmann T, Gian K, Kazmierczak B, Vollmer E. Lung carcinoma-associated atypical adenomatoid hyperplasia, squamous cell dysplasia, and chromosome alterations in non-neoplastic bronchial mucosa. LUNG CANCER 2005 Feb;47(2):205-214.

Droemann D, Albrecht D, Gerdes J, Ulmer A, Branscheid D, Vollmer E, Dalhoff K, Zabel P, Goldmann T. Human lung cancer cells express functionally active Toll-like receptor 9 [Internet]. RESPIRATORY RESEARCH 2005 Jan;6(1). DOI: 10.1186/1465-9921-6-1 Open Access

Loeschke S, Goldmann T, Vollmer E. Improved detection of mycobacterial DNA by PCR in formalin-fixed, paraffin-embedded tissues using thin sections. PATHOLOGY RESEARCH AND PRACTICE 2005;201(1):37-40.

Kayser K, Kosjerina Z, Goldmann T, Kayser G, Kazmierczak B, Vollmer E. Phenotype and genotype associations of lung carcinoma with atypical adenomatoid hyperplasia, squamous cell dysplasia, and chromosome alterations in non-neoplastic bronchial mucosa. ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY = REVUE ROUMAINE DE MORPHOLOGIE ET EMBRYOLOGIE 2005;46(1):5-10.

Goldmann T, Dromann D, Marzouki M, Schimmel U, Debel K, Branscheid D, Zeiser T, Rupp J, Gerdes J, Zabel P, Vollmer E. Tissue microarrays from HOPE-fixed specimens allow for enhanced high throughput molecular analyses in paraffin-embedded material. PATHOLOGY RESEARCH AND PRACTICE 2005;201(8-9):599-602.

2004 (Selection)

Rupp J, Droemann D, Goldmann T, Zabel P, Solbach W, Vollmer E, Branscheid D, Dalhoff K, Maass M. Alveolar epithelial cells type II are major target cells for C. pneumoniae in chronic but not in acute respiratory infection. FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY 2004 Jul;41(3):197-203.

Goldmann T, Flohr AM, Murua Escobar H, Gerstmayer B, Janssen U, Bosio A, Loeschke S, Vollmer E, Bullerdiek J. The HOPE-technique permits Northern blot and microarray analyses in paraffin-embedded tissues. PATHOLOGY RESEARCH AND PRACTICE 2004;200(7-8):511-515.

Seitenanfang