Priority Research Area Asthma and Allergy
Autoimmunity of the Lung
Mission
Projects
Funding
Techniques
Publications
Staff
Publications
2018
Yu, X, Riemekasten, G & Petersen, F 2018, 'Autoantibodies against muscarinic acetylcholine receptor M in Sjogren's syndrome and corresponding mouse models' Frontiers in bioscience (Landmark edition), Bd 23, S. 2053-2064.
Krauss-Etschmann, S, Yu, X, Petersen, F & Wen, L 2018, 'Autoantibodies in Chronic Obstructive Pulmonary Disease' Frontiers in Immunology, Bd 9, Nr. 66. DOI: doi: 10.3389/fimmu.2018.00066.
Yu, X & Petersen, F 2018, 'A methodological review of induced animal models of autoimmune diseases' AUTOIMMUNITY REVIEWS , Bd 17, Nr. 5, S. 473-479. DOI: 10.1016/j.autrev.2018.03.001
Weigold, F, Günther, J, Pfeiffenberger, M, Cabral-Marques, O, Siegert, E, Dragun, D, Philippe, A, Regensburger, A-K, Recke, A, Yu, X, Petersen, F, Catar, R, Biesen, R, Hiepe, F, Burmester, GR, Heidecke, H & Riemekasten, G 2018, 'Antibodies against chemokine receptors CXCR3 and CXCR4 predict progressive deterioration of lung function in patients with systemic sclerosis' ARTHRITIS RESEARCH & THERAPY , Bd 20, Nr. 1, S. 52. DOI: 10.1186/s13075-018-1545-8
Yu, X, Akbarzadeh, R, Pieper, M, Scholzen, T, Gehrig, S, Schultz, C, Zillikens, D, König, P & Petersen, F 2018, 'Neutrophil adhesion is a prerequisite for antibody-mediated proteolytic tissue damage in experimental epidermolysis bullosa acquisita' Journal of Investigative Dermatology. DOI: 10.1016/j.jid.2018.03.1499
Lamprecht, P, Kerstein, A, Klapa, S, Schinke, S, Karsten, CM, Yu, X, Ehlers, M, Epplen, JT, Holl-Ulrich, K, Wiech, T, Kalies, K, Lange, T, Laudien, M, Laskay, T, Gemoll, T, Schumacher, U, Ullrich, S, Busch, H, Ibrahim, S, Fischer, N, Hasselbacher, K, Pries, R, Petersen, F, Weppner, G, Manz, R, Humrich, JY, Nieberding, R, Riemekasten, G & Müller, A 2018, 'Pathogenetic and Clinical Aspects of Anti-Neutrophil Cytoplasmic Autoantibody-Associated Vasculitides' FRONTIERS IN IMMUNOLOGY, Bd 9, S. 680. DOI: 10.3389/fimmu.2018.00680
Yu, X, Kasprick, A, Hartmann, K & Petersen, F 2018, 'The Role of Mast Cells in Autoimmune Bullous Dermatoses' FRONTIERS IN IMMUNOLOGY, Bd 9, S. 386. DOI: 10.3389/fimmu.2018.00386
2017
Zheng, J, Huang, Q, Huang, R, Deng, F, Yue, X, Yin, J, Zhao, W, Chen, Y, Wen, L, Zhou, J, Huang, R, Riemekasten, G, Liu, Z, Petersen, F & Yu, X 2017, 'B Cells Are Indispensable for a Novel Mouse Model of Primary Sjögren's Syndrome' Frontiers in Immunology, Bd 8, S. 1384. DOI: 10.3389/fimmu.2017.01384
Deng, F, Chen, Y, Zheng, J, Huang, Q, Cao, X, Zillikens, D, Petersen, F & Yu, X 2017, 'CD11b-deficient mice exhibit an increased severity in the late phase of antibody transfer-induced experimental epidermolysis bullosa acquisita' EXPERIMENTAL DERMATOLOGY , Bd 26, Nr. 12, 12, S. 1175-1178. DOI: 10.1111/exd.13434
Petersen, F, Yue, X, Riemekasten, G & Yu, X 2017, 'Dysregulated homeostasis of target tissues or autoantigens - A novel principle in autoimmunity' AUTOIMMUNITY REVIEWS , Bd 16, Nr. 6, S. 602-611. DOI: 10.1016/j.autrev.2017.04.006
Michelfelder, M, Becker, W-M, Riedlinger, A, Siegert, E, Drömann, D, Yu, X, Petersen, F & Riemekasten, G 2017, 'Interstitial lung disease increases mortality in systemic sclerosis patients with pulmonary arterial hypertension without affecting hemodynamics and exercise capacity' Clinical Rheumatology, Bd 36, Nr. 2, S. 381-390. DOI: 10.1007/s10067-016-3504-6
Zhao, W, Yue, X, Liu, K, Zheng, J, Huang, R, Zou, J, Riemekasten, G, Petersen, F & Yu, X 2017, 'The status of pulmonary fibrosis in systemic sclerosis is associated with IRF5, STAT4, IRAK1, and CTGF polymorphisms' RHEUMATOLOGY INTERNATIONAL, Bd 37, Nr. 8, S. 1303-1310. DOI: 10.1007/s00296-017-3722-5
2016
Dankowski, T, Schröder, T, Möller, S, Yu, X, Ellinghaus, D, Bär, F, Fellermann, K, Lehnert, H, Schreiber, S, Franke, A, Sina, C, Ibrahim, SM & König, IR 2016, 'Male-specific association between MT-ND4 11719 A/G polymorphism and ulcerative colitis: a mitochondria-wide genetic association study' Zeitschrift für Gastroenterologie, Bd 16, Nr. 1, S. 118. DOI: 10.1186/s12876-016-0509-1
Akbarzadeh Najar, R, Yu, X, Vogl, T, Ludwig, RJ, Schmidt, E, Zillikens, D & Petersen, F 2016, 'Myeloid-related proteins-8 and -14 are expressed but dispensable in the pathogenesis of experimental epidermolysis bullosa acquisita and bullous pemphigoid' Journal of dermatological science, Bd 81, Nr. 3, S. 165-72., 10.1016/j.jdermsci.2015.12.001
Chen, Y, Zheng, J, Huang, Q, Deng, F, Huang, R, Zhao, W, Yin, J, Song, L, Chen, J, Gao, X, Liu, Z, Petersen, F & Yu, X 2016, 'Autoantibodies against the Second Extracellular Loop of M3R Do neither Induce nor Indicate Primary Sjögren's Syndrome' PLOS ONE, Bd 11, Nr. 2, S. e0149485., 10.1371/journal.pone.0149485
2015
Kemmer, A, Bieber, K, Abadpour, A, Yu, X, Mitschker, N, Roth, S, Kauderer, C, Ludwig, RJ, Seeger, K, Köhl, J, Zillikens, D, Recke, A 2015, 'A recombinant fusion protein derived from dog hookworm inhibits autoantibody-induced dermal-epidermal separation ex vivo' EXPERIMENTAL DERMATOLOGY ., 10.1111/exd.12804
Yu, X, Kasprick, A, Petersen, F 2015, 'Revisiting the role of mast cells in autoimmunity' AUTOIMMUNITY REVIEWS , Bd 14, Nr. 9, S. 751-9., 10.1016/j.autrev.2015.04.008
Chen, Y, Deng, F, Zheng, J, Yin, J, Huang, R, Liu, W, Lin, Q, Gao, Y, Gao, X, Yu, X, Liu, Z, Chen, J 2015, 'High circulating level of interleukin-18 in patients with primary Sjögren's syndrome is associated with disease activity' Mod Rheumatol, S. 1-3., 10.3109/14397595.2015.1021409
Kasprick, A, Yu, X, Scholten, J, Hartmann, K, Pas, HH, Zillikens, D, Ludwig, RJ, Petersen, F 2015, 'Conditional depletion of mast cells has no impact on the severity of experimental epidermolysis bullosa acquisita' European journal of immunology, Bd 45, Nr. 5, S. 1462-70., 10.1002/eji.201444769
Zheng, J, Huang, R, Huang, Q, Deng, F, Chen, Y, Yin, J, Chen, J, Wang, Y, Shi, G, Gao, X, Liu, Z, Petersen, F, Yu, X 2015, 'The GTF2I rs117026326 polymorphism is associated with anti-SSA-positive primary Sjögren's syndrome' RHEUMATOLOGY, Bd 54, Nr. 3, S. 562-564., 10.1093/rheumatology/keu466
Huang, R, Yin, J, Chen, Y, Deng, F, Chen, J, Gao, X, Liu, Z, Yu, X, Zheng, J 2015, 'The amino acid variation within the binding pocket 7 and 9 of HLA-DRB1 molecules are associated with primary Sjögren's syndrome' Journal of autoimmunity, Bd 57, S. 53-9., 10.1016/j.jaut.2014.11.006
Yu, X, Huang, Q, Petersen, F 2015, 'History and milestones of mouse models of autoimmune diseases' CURRENT PHARMACEUTICAL DESIGN , Bd 21, Nr. 18, S. 2308-19.
Deng, F, Chen, J, Zheng, J, Chen, Y, Huang, R, Yin, J, Gao, X, Lin, Q, Huang, C, Gao, Y, Yu, X, Liu, Z 2015, 'Association of BAFF and IL-17A with subphenotypes of primary Sjögren's syndrome' International journal of rheumatic diseases., 10.1111/1756-185X.12569
Yu, X 2015, 'Autoimmune diseases: What have we learned from mice?' CURRENT PHARMACEUTICAL DESIGN , Bd 21, Nr. 18, S. 2306-7.
2014
Zheng, J, Chen, Y, Deng, F, Huang, R, Petersen, F, Ibrahim, S, Yu, X 2014, 'mtDNA sequence, phylogeny and evolution of laboratory mice' MITOCHONDRION, Bd 17, S. 126-131., 10.1016/j.mito.2014.07.006
Zheng, J, Petersen, F, Yu, X 2014, 'The role of PTPN22 in autoimmunity:Learning from mice.' AUTOIMMUNITY REVIEWS , Bd 13, Nr. 3, S. 266-271., 10.1016/j.autrev.2013.10.011
Yu, X, Zheng, J, Collin, M, Schmidt, E, Zillikens, D, Petersen, F 2014, 'EndoS Reduces the Pathogenicity of Anti-mCOL7 IgG through Reduced Binding of Immune Complexes to Neutrophils' PLOS ONE, Bd 9, Nr. 2, S. e85317., 10.1371/journal.pone.0085317
2008-2013
Zheng, J, Yin, J, Huang, R, Petersen, F, Yu, X 2013, 'Meta-analysis reveals an association of STAT4 polymorphisms with systemic autoimmune disorders and anti-dsDNA antibody' HUMAN IMMUNOLOGY , Bd 74, Nr. 8, S. 986-92., 10.1016/j.humimm.2013.04.034
Zheng, J, Ibrahim, S, Petersen, F, Yu, X 2012, 'Meta-analysis reveals an association of PTPN22 C1858T with autoimmune diseases, which depends on the localization of the affected tissue' GENES AND IMMUNITY, Bd 13, Nr. 8, S. 641-652., 10.1038/gene.2012.46
Kasperkiewicz, M, Nimmerjahn, F, Wende, S, Hirose, M, Iwata, H, Jonkman, MF, Samavedam, U, Gupta, Y, Möller, S, Rentz, E, Hellberg, L, Kalies, K, Yu, X, Schmidt, E, Häsler, R, Laskay, T, Westermann, J, Köhl, J, Zillikens, D & Ludwig, RJ 2012, 'Genetic identification and functional validation of FcγRIV as key molecule in autoantibody-induced tissue injury' AMERICAN JOURNAL OF PATHOLOGY, Bd 228, Nr. 1, S. 8-19., 10.1002/path.4023
Yu, X, Ibrahim, SM 2011, 'Evidence of a role for Th17 cells in the breach of immune tolerance in arthritis' ARTHRITIS RESEARCH THERAPY , Bd 13, Nr. 5, S. 132., 10.1186/ar3490
Yu, X, Holdorf, K, Kasper, B, Zillikens, D, Ludwig, RJ & Petersen, F 2010, 'FcγRIIA and FcγRIIIB are required for autoantibody-induced tissue damage in experimental human models of bullous pemphigoid' Journal of Investigative Dermatology, Bd 130, Nr. 12, S. 2841-4., 10.1038/jid.2010.230
Tu-Rapp, H, Pu, L, Marques, A, Kulisch, C, Yu, X, Gierer, P, Ibrahim, SM, Vollmar, B 2010, 'Genetic control of leucocyte--endothelial cell interaction in collagen-induced arthritis' ANNALS OF THE RHEUMATIC DISEASES , Bd 69, Nr. 3, S. 606-10., 10.1136/ard.2009.100636
Mikkat, S, Lorenz, P, Scharf, C, Yu, X, Glocker, MO, Ibrahim, SM 2010, 'MS characterization of qualitative protein polymorphisms in the spinal cords of inbred mouse strains' Proteomics, Bd 10, Nr. 5, S. 1050-62., 10.1002/pmic.200800932
Bieber, K, Sun, S, Ishii, N, Kasperkiewicz, M, Schmidt, E, Hirose, M, Westermann, J, Yu, X, Zillikens, D, Ludwig, RJ 2010, 'Animal models for autoimmune bullous dermatoses' EXPERIMENTAL DERMATOLOGY , Bd 19, Nr. 1, S. 2-11., 10.1111/j.1600-0625.2009.00948.x
Petersen, F, Yu, X 2010, 'A novel preclinical model for rheumatoid arthritis research' ARTHRITIS RESEARCH & THERAPY , Bd 12, Nr. 6, S. 148., 10.1186/ar3181
Yu, X, Wester-Rosenlöf, L, Gimsa, U, Holzhueter, S-A, Marques, A, Jonas, L, Hagenow, K, Kunz, M, Nizze, H, Tiedge, M, Holmdahl, R, Ibrahim, SM 2009, 'The mtDNA nt7778 G/T polymorphism affects autoimmune diseases and reproductive performance in the mouse' HUMAN MOLECULAR GENETICS , Bd 18, Nr. 24, S. 4689-98., 10.1093/hmg/ddp432
Yu, X, Wieczorek, S, Franke, A, Yin, H, Pierer, M, Sina, C, Karlsen, TH, Boberg, KM, Bergquist, A, Kunz, M, Witte, T, Gross, WL, Epplen, JT, Alarcón-Riquelme, ME, Schreiber, S, Ibrahim, SM 2009, 'Association of UCP2 -866 G/A polymorphism with chronic inflammatory diseases' GENES AND IMMUNITY, Bd 10, Nr. 6, S. 601-5., 10.1038/gene.2009.29
Yu, X, Teng, H, Marques, A, Ashgari, F, Ibrahim, SM 2009, 'High resolution mapping of Cia3: a common arthritis quantitative trait loci in different species' JOURNAL OF IMMUNOLOGY, Bd 182, Nr. 5, S. 3016-23., 10.4049/jimmunol.0803005
Yu, X, Gimsa, U, Wester-Rosenlöf, L, Kanitz, E, Otten, W, Kunz, M, Ibrahim, SM 2009, 'Dissecting the effects of mtDNA variations on complex traits using mouse conplastic strains' GENOME RESEARCH, Bd 19, Nr. 1, S. 159-65., 10.1101/gr.078865.108
Yu, X, Koczan, D, Sulonen, A-M, Akkad, DA, Kroner, A, Comabella, M, Costa, G, Corongiu, D, Goertsches, R, Camina-Tato, M, Thiesen, H-J, Nyland, HI, Mørk, SJ, Montalban, X, Rieckmann, P, Marrosu, MG, Myhr, K-M, Epplen, JT, Saarela, J, Ibrahim, SM 2008, 'mtDNA nt13708A variant increases the risk of multiple sclerosis' PL0S ONE, Bd 3, Nr. 2, S. e1530., 10.1371/journal.pone.0001530