Priority Research Area Infections

Host ­Determinants in Lung Infections

Mission   Projects   Funding   Techniques   Publications    Staff

Key Projects

Vaccines:

  • Molecular basis of sex-dependency in vaccine efficacy

 

B cells

  • Elucidate the sex-specific role of B cells in TB
  • B cell development in the bone-marrow during chronic infection

 

Myeloid cells

  • Sex-specific regulation and function of monocytes and macrophages in TB
  • Sex-specific regulation of immunoproteasome function in lung infection (Meiners/Schneider)

 

Coinfection

  • Viral triggers of TB disease: Impact of influenza or MCMV on TB disease and Mtb-specific immunity