Priority Research Area Infections

Host ­Determinants in Lung Infections

Mission   Projects   Funding   Techniques   Publications    Staff

Key Projects

Vaccines:

• Molecular basis of sex-dependency in vaccine efficacy

B cells

• Elucidate the sex-specific role of B cells in TB
• B cell development in the bone-marrow during chronic infection

Myeloid cells

• Sex-specific regulation and function of monocytes and macrophages in TB
• Sex-specific regulation of immunoproteasome function in lung infection (Meiners/Schneider)

Coinfection

• Viral triggers of TB disease: Impact of influenza or MCMV on TB disease and Mtb-specific immunity