Priority Research Area Infections

Host-Microbe Interactome

Mission   Projects   Funding   Techniques   Publications   Staff



Listian SA, Kol M, Ufelmann E, Eising S, Fröhlich F, Walter S, Holthuis JCM,  Barisch C (2023). Complex sphingolipid profiling and identification of an inositol phosphorylceramide synthase in Dictyostelium discoideum. BioRxiv.

*Franzkock R, *Anand A, Psathaki OE, Barisch C (2023). Resolving exit strategies of mycobacteria by combining high-pressure freezing with 3D-correlative light and electron microscopy. BioRxiv. *authors contributed equally

​Anand A, Mazur A-C, Rosell-Arevalo P, Franzkoch R, Breitsprecher L, Listian SA, Hüttel SV, Müller D, Schäfer DG, Vormittag S, Hilbi H, Maniak M, Gutierrez MG, Barisch C (2023). ER-dependent membrane repair of mycobacteria-induced vacuole damage. BioRxiv and accepted for publication in mBio.

Barisch C, Holthuis JCM, Cosentino K (2023). Membrane damage and repair: A thin line between life and death. Biol. Chem. REVIEW.

Vormittag S, Hüsler D, Haneburger I, Kroniger T, Anand A, Prantl M, Barisch C, Maaß S, Becher D, Letourneur F, Hilbi H (2023). Legionella- and host-driven lipid flux at LCV-ER membrane contact sites promotes vacuole remodeling.  EMBO Rep.



Foulon M, Listian S A, Soldati T, Barisch C (2022). Chapter 6. Conserved mechanisms drive host lipid access, import and utilisation in Mycobacterium tuberculosis and M. marinum. In Developments in Microbiology, Biology of Mycobacterial Lipids, Academic Press. Edited by Fatima Z, Canaan S. REVIEW.



Hanna N, Koliwer-Brandl H, Lefrançois L H, Kalinina V, Cardenal-Muñoz E, Appiah J, Leuba F, Hilbi H, Soldati T and Barisch C (2021). Zn2+ intoxication of Mycobacterium marinum during Dictyostelium discoideum infection is counteracted by induction of the pathogen Zn2+ exporter CtpC. mBio.

Niekamp P, Guzman G, Leier HC, Rashidfarrokhi A, Richina V, Pott F, Barisch C, Holthuis JCM, Tafesse FG (2021). Sphingomyelin biosynthesis is essential for phagocytic signaling during Mycobacterium tuberculosis host cell entry. mBio.



Knobloch P, Koliwer-Brandl H, Arnold FM, Hanna N, Gonda I, Adenau S, Personnic N, Barisch C, Seeger MA, Soldati T & Hilbi H (2020). Mycobacterium marinum produces distinct mycobactin and carboxymycobactin siderophores to promote growth in broth and phagocytes. Cell Microbiol.



Luscher A, Fröhlich F, Barisch C, Littlewood C, Metcalfe J, Leuba F, Palma A, Pirruccello M, Cesareni G, Stagi M, Walther TC, Soldati T, De Camilli P and Swan LE (2019). Lowe syndrome-linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum. Mol Biol Cell.

Koliwer-Brandl H, Knobloch P, Barisch C, Welin A, Hanna N, Soldati T and Hilbi H (2019). Distinct Mycobacterium marinum phosphatases determine pathogen vacuole phosphoinositide pattern, phagosome maturation, and escape to the cytosol. Cell Microbiol.

López-Jiménez AT, Cardenal-Muñoz E, Leuba F, Gerstenmaier L, Barisch C, Hagedorn M, King JS and Soldati T (2019). The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infection. PLoS Pathog.



Barisch C, Kalinina V, Lefrançois LH, Appiah J, López-Jiménez AT and Soldati T (2018). Localization of all four ZnT zinc transporters in Dictyostelium and impact of ZntA and ZntB knockout on bacteria killing. J Cell Sci.

Sattler N, Bosmani C, Barisch C, Guého A, Gopaldass N, Dias M, Leuba F, Bruckert F, Cosson P and Soldati T (2018). Functions of the Dictyostelium LIMP-2 and CD36 homologues in bacteria uptake, phagolysosome biogenesis and host cell defence. J Cell Sci.

Watkins RA, Andrews A, Wynn C, Barisch C, King JS and Johnston SA (2018). Cryptococcus neoformans Escape From Dictyostelium Amoeba by Both WASH-Mediated Constitutive Exocytosis and Vomocytosis. Front Cell Infect Microbiol.

Cardenal-Muñoz E, Barisch C, Lefrançois LH, López-Jiménez AT and Soldati T (2018). When Dicty Met Myco, a (Not So) Romantic Story about One Amoeba and Its Intracellular Pathogen. Front Cell Infect Microbiol. REVIEW.

Dunn JD, Bosmani C, Barisch C, Raykov L, Lefrançois LH, Cardenal-Muñoz E, López-Jiménez AT and Soldati T (2018). Eat Prey, Live: Dictyostelium discoideum As a Model for Cell-Autonomous Defenses. Front Immunol. REVIEW.



Barisch C and Soldati T (2017). Breaking fat! How mycobacteria and other intracellular pathogens manipulate host lipid droplets. Biochimie. REVIEW.

Barisch C and Soldati T (2017). Mycobacterium marinum Degrades Both Triacylglycerols and Phospholipids from Its Dictyostelium Host to Synthesise Its Own Triacylglycerols and Generate Lipid Inclusions. PLoS Pathog. Video clip (in French) on Radio Television Suisse:



Barisch C, López-Jiménez AT and Soldati T (2015). Live imaging of Mycobacterium marinum infection in Dictyostelium discoideum. Methods Mol Biol. BOOK CHAPTER.

Barisch C, Paschke P, Hagedorn M, Maniak M and Soldati T (2015). Lipid droplet dynamics at early stages of Mycobacterium marinum infection in Dictyostelium. Cell Microbiol.



Du X, Barisch C, Paschke P, Herrfurth C, Bertinetti O, Pawolleck N, Otto H, Rühling H, Feussner I, Herberg FW and Maniak M (2013). Dictyostelium lipid droplets host novel proteins. Eukaryot Cell.