Medicine
Center for Clinical Studies Borstel
Mission 
Projects Techniques Publications Staff
Publications
2020
Andres, S, Merker, M, Heyckendorf, J, Kalsdorf, B, Rumetshofer, R, Indra, A, Hofmann-Thiel, S, Hoffmann, H, Lange, C, Niemann, S & Maurer, FP 2020, 'Bedaquiline-resistant Tuberculosis: Dark Clouds on the Horizon', American journal of respiratory and critical care medicine. https://doi.org/10.1164/rccm.201909-1819LE
Eggeling, J, Heyckendorf, J, Lange, C, Maier, C, Reimann, M, Sassmann-Schweda, A, Shaikh, R, Herzmann, C & Luethgen, M 2020, 'Changes in taste and smell as an early marker for COVID-19', INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES , Jg. 99, S. 8-9. https://doi.org/10.1016/j.ijid.2020.07.018
Jünger, C, Reimann, M, Krabbe, L, Gaede, KI, Lange, C, Herzmann, C & Rüller, S 2020, 'Non-invasive ventilation with pursed lips breathing mode for patients with COPD and hypercapnic respiratory failure: A retrospective analysis', PLOS ONE, Jg. 15, Nr. 9, S. e0238619. https://doi.org/10.1371/journal.pone.0238619
Suárez, I, Gruell, H, Heyckendorf, J, Fünger, S, Lichtenstein, T, Jung, N, Lehmann, C, Unnewehr, M, Fätkenheuer, G, Lange, C & Rybniker, J 2020, 'Intensified adjunctive corticosteroid therapy for CNS tuberculomas', Infection. https://doi.org/10.1007/s15010-019-01378-3
WILLOW Investigators & Herzmann, C 2020, 'Phase 2 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis', New England Journal of Medicine. https://doi.org/10.1056/NEJMoa2021713
2019
Webering, S, Lunding, LP, Vock, C, Schröder, A, Gaede, KI, Herzmann, C, Fehrenbach, H & Wegmann, M 2019, 'The alpha-melanocyte-stimulating hormone acts as a local immune homeostasis factor in experimental allergic asthma', Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, Jg. 49, Nr. 7, S. 1026-1039. https://doi.org/10.1111/cea.13400
2018
ATLANTIC Investigators & Herzmann, C 2018, 'Durvalumab as third-line or later treatment for advanced non-small-cell lung cancer (ATLANTIC): an open-label, single-arm, phase 2 study' Lancet Oncology, Jg. 19, Nr. 4, S. 521-536.
Silkoff, PE, Flavin, S, Gordon, R, Loza, MJ, Sterk, PJ, Lutter, R, Diamant, Z, Turner, RB, Lipworth, BJ, Proud, D, Singh, D, Eich, A, Backer, V, Gern, JE, Herzmann, C, Halperin, SA, Mensinga, TT, Del Vecchio, AM, Branigan, P, San Mateo, L, Baribaud, F, Barnathan, ES & Johnston, SL 2018, 'TLR3 Blockade in Rhinovirus-Induced Experimental Asthma Exacerbations: A Randomized Controlled Study' The Journal of allergy and clinical immunology. https://doi.org/10.1016/j.jaci.2017.06.027
Convert Study Group, Herzmann, C, Griffith, DE & Winthrop, KL 2018, 'Amikacin Liposome Inhalation Suspension for Treatment-Refractory Lung Disease Caused by Mycobacterium avium Complex (CONVERT): A Prospective, Open-Label, Randomized Study.' American journal of respiratory and critical care medicine. https://doi.org/10.1164/rccm.201807-1318OC
Salzer, HJF, Prattes, J, Flick, H, Reimann, M, Heyckendorf, J, Kalsdorf, B, Obersteiner, S, Gaede, KI, Herzmann, C, Johnson, GL, Lange, C & Hoenigl, M 2018, 'Evaluation of Galactomannan Testing, the Aspergillus-Specific Lateral-Flow Device Test and Levels of Cytokines in Bronchoalveolar Lavage Fluid for Diagnosis of Chronic Pulmonary Aspergillosis' Frontiers in Microbiology, Jg. 9, S. 2223.
IMPULSE study team & Herzmann, C 2018, 'Immunotherapeutic maintenance treatment with toll-like receptor 9 agonist lefitolimod in patients with extensive-stage small-cell lung cancer: results from the exploratory, controlled, randomized, international phase II IMPULSE study' Annals of oncology : official journal of the European Society for Medical Oncology / ESMO, Jg. 29, Nr. 10, S. 2076-2084.
Herzmann, C, Dallenga, T & Kalinke, U 2018, 'Pulmonale Immunität bei Tuberkulose' PNEUMOLOGIE, Jg. 72, S. 1-10.
Herzmann, C, Lange, C & Günther, G 2018, Tuberkulose (TB). in C Hoffmann & J Rockstroh (Hrsg.), HIV Buch 2018/2019. Medizin Fokus Verlag, Hamburg, S. 340-351.
2017
Herzmann, C, Ernst, M, Lange, C, Stenger, S, Kaufmann, SHE, Reiling, N, Schaberg, T, van der Merwe, L, Maertzdorf, J & Tb or not Tb consortium 2017, 'Pulmonary immune responses to Mycobacterium tuberculosis in exposed individuals' PLOS ONE, Bd 12, Nr. 11, S. e0187882. DOI: 10.1371/journal.pone.0187882
Bahmer, T, Waschki, B, Schatz, F, Herzmann, C, Zabel, P, Kirsten, A-M, Rabe, KF, Watz, H & ERA-Study Group 2017, 'Physical activity, airway resistance and small airway dysfunction in severe asthma' The European respiratory journal, Bd 49, Nr. 1, S. pii 1601827. DOI: 10.1183/13993003.01827-2016
Herzmann, C, Golakov, M, Malekzada, F, Lonnroth, K & Kranzer, K 2017, 'Radiological screening of refugees in Germany' The European respiratory journal, Bd 49, Nr. 5. DOI: 10.1183/13993003.02487-2016
Labugger, I, Heyckendorf, J, Dees, S, Häussinger, E, Herzmann, C, Kohl, TA, Richter, E, Rivera-Milla, E & Lange, C 2017, 'Detection of transrenal DNA for the diagnosis of pulmonary tuberculosis and treatment monitoring' INFECTION, Bd 45, Nr. 3, S. 269-276. DOI: 10.1007/s15010-016-0955-2
Nakiwala, D, Kellgren, L, Herzmann, C, Olaru, ID, Brown, M, Ferrand, RA, Khan, P & Kranzer, K 2017, 'Language discordance between tuberculosis patients and healthcare providers challenging universal access' The European respiratory journal, Bd 49, Nr. 4. DOI: 10.1183/13993003.00116-2017
Silkoff, PE, Flavin, S, Gordon, R, Loza, MJ, Sterk, PJ, Lutter, R, Diamant, Z, Turner, RB, Lipworth, BJ, Proud, D, Singh, D, Eich, A, Backer, V, Gern, JE, Herzmann, C, Halperin, SA, Mensinga, TT, Del Vecchio, AM, Branigan, P, San Mateo, L, Baribaud, F, Barnathan, ES & Johnston, SL 2017, 'TLR3 Blockade in Rhinovirus-Induced Experimental Asthma Exacerbations: A Randomized Controlled Study' The Journal of allergy and clinical immunology. DOI: 10.1016/j.jaci.2017.06.027
2016
Busch, M, Herzmann, C, Kallert, S, Zimmermann, A, Höfer, C, Mayer, D, Zenk, SF, Muche, R, Lange, C, Bloom, BR, Modlin, RL, Stenger, S & TBornotTB Network 2016, 'Lipoarabinomannan-responsive Polycytotoxic T Cells are Associated With Protection in Human Tuberculosis' American journal of respiratory and critical care medicine, Bd 194, Nr. 3, S. 345-55. DOI: 10.1164/rccm.201509-1746OC
Herzmann, C, Sotgiu, G, Bellinger, O, Diel, R, Gerdes, S, Goetsch, U, Heykes-Uden, H, Schaberg, T, Lange, C & TB or not TB consortium 2016, 'Risk for latent and active tuberculosis in Germany' INFECTION. DOI: 10.1007/s15010-016-0963-2
Salzer, HJF, Wassilew, N, Köhler, N, Olaru, ID, Günther, G, Herzmann, C, Kalsdorf, B, Sanchez-Carballo, P, Terhalle, E, Rolling, T, Lange, C & Heyckendorf, J 2016, 'Personalized Medicine for Chronic Respiratory Infectious Diseases: Tuberculosis, Nontuberculous Mycobacterial Pulmonary Diseases, and Chronic Pulmonary Aspergillosis' RESPIRATION, Bd 92, Nr. 4, S. 199-214. DOI: 10.1159/000449037
2015
Herzmann C, Sotgiu G, Schaberg T, Ernst M, Stenger S, Lange C; TB or not TB Consortium. Childhood BCG vaccination does not influence control of Mycobacterium tuberculosis growth by human bronchoalveolar lavage cells. TUBERCULOSIS (Edinb). 2015 May;95(3):321-7. doi: 10.1016/j.tube.2015.02.044. Epub 2015 Feb 28.
2014
Herzmann, C, Sotgiu, G, Schaberg, T, Ernst, M, Stenger, S, Lange, C & Consortium for the German TB or Not TB9 2014, 'Early BCG vaccination is unrelated to pulmonary immunity against Mycobacterium tuberculosis in adults' The European respiratory journal., 10.1183/09031936.00086514
2013
Reiling N, Homolka S, Walter K, Brandenburg J, Niwinski L, Ernst M, Herzmann C, Lange C, Diel R, Ehlers S, Niemann S. Clade-specific virulence patterns of Mycobacterium tuberculosis complex strains in human primary macrophages and aerogenically infected mice. MBio. 2013 Jul 30;4(4). pii: e00250-13. doi: 10.1128/mBio.00250-13.
2012
Herzmann C, Lange C, Schaberg T, Ernst M, Ehlers S; for The TB or Not TB Consortium. Immunological Evidence of Incipient Pulmonary Tuberculosis. J Infect Dis. 2012 Nov;206(10):1630-1631. Epub 2012 Sep 10
Günther G, Heyckendorf J, Herzmann C, Lange C. [Tuberculosis]. Dtsch Med Wochenschr. 2012 May;137(18):947-58; quiz 959-62. Epub 2012 Apr 26. Review.
Heyckendorf J, Kalsdorf B, Herzmann C, Günther G, Lange C, Tuberkulose – State of the Art. Kompendium Pneumologie 2012(1) 1, Georg Thieme Verlag KG
Günther G, Heyckendorf J, Herzmann C, Lange C. Tuberculosis. Dtsch Med Wochenschr. 2012 May;137(18):947-62. Epub 2012 Apr 26.
Herzmann C, Ernst M, Ehlers S, Stenger S, Maertzdorf J, Sotgiu G, Lange C. Increased frequencies of pulmonary Treg cells in latent M. tuberculosis infection. Eur Respir J. 2012 Mar 22.
2011
Lange C, Herzmann C, Migliori GB, Gori A. Tuberculosis. p354-69 In: Hoffmann C, Rockstroh J. HIV Book 2011. Medizin Fokus Verlag, Hamburg. ISBN 978-3-941727-08-3
Herzmann C, Lange C, Stenger S, Maertzdorf J, Schaberg T, Sotgiu G, Ernst M. Latent tuberculosis infection is associated with an increased frequency of Treg cells in the bronchoalveolar lavage. Europ Respir Soc, Ann Congress 2011, Sep 24-28, Amsterdam, Poster 1809
Lange C, Herzmann C, Tuberkulose. P350-62. In: Hoffmann C, Rochstroh J. HIV Buch 2011. Medizin Fokus Verlag, Hamburg. ISBN-13: 978-3-941727-03-8
Herzmann C, Esser S, Lange C. Infections with non-tuberculous mycobacteria in HIV-infected patients. Hautarzt. 2011 Apr;62(4):272-9
2010
Herzmann C, Smith C, Johnson MA, Byrne P, Terenghi G, et al. A Prospective, Double Blind, Randomised, Placebo Controlled Trial Evaluating Acetyl-L-Carnitine (ALCAR) for the Prevention of Distal Symmetric Polyneuropathy in HIV Infected Individuals. J AIDS Clinic Res 2010; 1:108. doi:10.4172/2155-6113.1000108
Herzmann C., Lange C. Infections with non-tuberculous mycobacteria and HIV. Dtsch Med Wochenschr. 2010 Jun;135(23):1192-7. Epub 2010 May 31.
2009
Herzmann C., Arastéh K., Efavirenz induced osteomalacia. AIDS. 2009 Jan 14;23(2):274-5
2008
Herzmann C., Jansen V. and Lichey J.. Bronchial cast formation associated with loss of immunoglobulin and calcium. Thorax, Aug 2008; 63: 754.
Herzmann C., Cuthbertson Z., Fosdick L., Fisher M., Nelson M., Perry N., Law M., Wand H., Janossy G., Johnson M.A., Youle M. Long-term clinical and surrogate marker effects of subcutaneous intermittent interleukin-2 without antiretroviral therapy in HIV-infected patients. J Antimicrob Chemother. 2008 Jun 27
Herzmann C., Whiting S.J., Thomas M., Byrne P., Johnson M.A., Youle M. Pharmacokinetics of Acetyl-L-Carnitine Given in Single or Multiple Doses to HIV-1 Infected Patients with Toxic Peripheral Polyneuropathy. The Open AIDS J 2008;2:39-42(4)
2007
Stocker H., Herzmann C., Breske A., Kruse G., Berger M., Schulbin H., Hill A., Steinmüller J., Becker M., Arastéh K., Kurowski M., Saquinavir, Nelfinavir and M8 pharmacokinetics following Ritonavir and Nelfinavir administration. J Antimicrob Chemother. 2007 Mar;59(3):560-4
2006
Youle M., Emery S., Fisher M., Nelson M., Fosdick L., Janossy G., Loveday C., Sullivan A., Herzmann C., et al., A randomised trial of subcutaneous intermittent interleukin-2 without antiretroviral therapy in HIV-infected patients: The UK-Vanguard study. PLoS Clin Trials 1(1): e3. DOI: 10. 1371/journal.pctr.0010003, 2006 May
Stocker H, Kloft C, Plock N, Breske A, Kruse G, Herzmann C, Schulbin H, Kreckel P, Weber C, Goebel F, Roeling J, Staszewski S, Plettenberg A, Moecklinghoff C, Arasteh K, Kurowski M. Pharmacokinetics of enfuvirtide in patients treated in typical routine clinical settings. Antimicrob Agents Chemother. 2006 Feb;50(2):667-73.
2005
Herzmann C, Johnson MA, Youle M, Long-term effect of acetyl-L-carnitine for antiretroviral toxic neuropathy. HIV Clinical Trials 2005 Nov/Dec; 6(6): 344-350
Herzmann C, Kinloch S, Johnson MA (2005) Rash in an HIV-positive patient. HIV Medicine 2005 Nov; 6(6): 379
Herzmann C, Arastèh K, Murphy RL, Schulbin H, Kreckel P, Drauz D, Schinazi RF, Beard A, Cartee L, Otto MJ. Safety, Pharmacokinetics and Efficacy of Racivir with Efavirenz and Stavudine in antiretroviral-naïve HIV-infected patients (AAC00901-04) Antimicrob Agents Chemother. 2005 Jul;49(7): 2828-33
2004
Stocker, H., Kruse, G., Kreckel, P., Herzmann, C., Arasteh, K., Claus, J., Jessen, H., Cordes, C., Hintsche, B., Schlote, F., Schneider, L., Kurowski, M., (2004) Nevirapine significantly reduces the levels of racemic methadone and (R)-methadone in human immunodeficiency virus-infected patients. Antimicrob Agents Chemother. 2004 Nov;48(11):4148-53
Herzmann, C., Karcher, H., (2004) Nevirapine plus zidovudine to prevent mother-to-child transmission of HIV (Correspondence). N Engl J Med. 351(19):2013-5
Stocker, H., Kruse, G., Arastéh, A., Breske, A., Herzmann, C., Izbicki, D., Möcklinghoff, C., Hill, A., Kurowski, M., (2004) Pharmacokinetic interaction between Saquinavir/r and Nelfinavir in HIV-infected patients. (Poster 2058 at the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy, ICAAC, Washington DC)
2003
Stocker, H., Kruse, G., Kreckel, P., Herzmann, C., Arastéh, K., Eskoetter, H., Claus, J., Jessen, H., Cordes, C., Hintsche, B., Schlote, F., Schneider, L., Kurowski, M. (2003) Nevirapine (NVP) significantly reduces methadone levels in HIV infected patients. (Poster for the 2nd International AIDS-Society Conference on HIV Pathogenesis and Treatment, Paris)
2002
Herzmann, C., (2002) Interferon assay compared to tuberculin skin testing for latent tuberculosis detection. (Correspondence). JAMA. 2002 Jan 23-30; 287(4): 451-2.