Medicine

2023

Hamada, Y, Gupta, RK, Quartagno, M, Izzard, A, Acuna-Villaorduna, C, Altet, N, Diel, R, Dominguez, J, Floyd, S, Gupta, A, Huerga, H, Jones-López, EC, Kinikar, A, Lange, C, van Leth, F, Liu, Q, Lu, W, Lu, P, Rueda, IL, Martinez, L, Mbandi, SK, Muñoz, L, Padilla, ES, Paradkar, M, Scriba, T, Sester, M, Shanaube, K, Sharma, SK, Sloot, R, Sotgiu, G, Thiruvengadam, K, Vashishtha, R, Abubakar, I & Rangaka, MX 2023, 'Predictive performance of interferon-gamma release assays and the tuberculin skin test for incident tuberculosis: an individual participant data meta-analysis', EClinicalMedicine, Jg. 56, S. 101815. https://doi.org/10.1016/j.eclinm.2022.101815

Lange, C, Köhler, N & Günther, G 2023, 'Regimens for Drug-Resistant Tuberculosis', New England Journal of Medicine, Jg. 388, Nr. 2, S. 189-191. https://doi.org/10.1056/NEJMc2213970

Vierbuchen, T, Agarwal, S, Johnson, JL, Galia, L, Lei, X, Stein, K, Olagnier, D, Gaede, KI, Herzmann, C, Holm, CK, Heine, H, Pai, A, O'Hara Hall, A, Hoebe, K & Fitzgerald, KA 2023, 'The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2', PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Jg. 120, Nr. 1, S. e2213715120. https://doi.org/10.1073/pnas.2213715120

 

2022

Alter, P, Kahnert, K, Trudzinski, FC, Bals, R, Watz, H, Speicher, T, Söhler, S, Andreas, S, Welte, T, Rabe, KF, Wouters, EFM, Sassmann-Schweda, A, Wirtz, H, Ficker, JH, Vogelmeier, CF & Jörres, RA 2022, 'Disease Progression and Age as Factors Underlying Multimorbidity in Patients with COPD: Results from COSYCONET', International journal of chronic obstructive pulmonary disease, Jg. 17, S. 1703-1713. https://doi.org/10.2147/COPD.S364812

Brandenburg, J, Heyckendorf, J, Marwitz, F, Zehethofer, N, Linnemann, L, Gisch, N, Karaköse, H, Reimann, M, Kranzer, K, Kalsdorf, B, Sanchez-Carballo, P, Weinkauf, M, Scholz, V, Malm, S, Homolka, S, Gaede, KI, Herzmann, C, Schaible, UE, Hölscher, C, Reiling, N & Schwudke, D 2022, 'Tuberculostearic Acid-Containing Phosphatidylinositols as Markers of Bacterial Burden in Tuberculosis', ACS infectious diseases, Jg. 8, Nr. 7, S. 1303-1315. https://doi.org/10.1021/acsinfecdis.2c00075

Chesov, E, Chesov, D, Maurer, FP, Andres, S, Utpatel, C, Barilar, I, Donica, A, Reimann, M, Niemann, S, Lange, C, Crudu, V, Heyckendorf, J & Merker, M 2022, 'Emergence of bedaquiline resistance in a high tuberculosis burden country', The European respiratory journal, Jg. 59, Nr. 3, 2100621. https://doi.org/10.1183/13993003.00621-2021

Freundt, K, Herzmann, C, Biedziak, D, Scheffzük, C, Gaede, KI & Stamme, C 2022, 'Surfactant protein A enhances the degradation of LPS-induced TLR4 in primary alveolar macrophages involving Rab7, β-arrestin2, and mTORC1', INFECTION AND IMMUNITY , Jg. 90, Nr. 2, S. e0025021. https://doi.org/10.1128/IAI.00250-21

Lüthgen, M, Rüller, S & Herzmann, C 2022, 'Characteristics of the deventilation syndrome in COPD patients treated with non-invasive ventilation: an explorative study', RESPIRATORY RESEARCH , Jg. 23, Nr. 1, S. 13. https://doi.org/10.1186/s12931-022-01924-y

 

2021

ALLIANCE Study Group, Abdo, M, Trinkmann, F, Kirsten, A-M, Pedersen, F, Herzmann, C, von Mutius, E, Kopp, MV, Hansen, G, Waschki, B, Rabe, KF, Watz, H & Bahmer, T 2021, 'Small Airway Dysfunction Links Asthma Severity with Physical Activity and Symptom Control', Journal of Allergy and Clinical Immunology in Clinical Practice, Jg. 9, Nr. 9, S. 3359-3368.e1. https://doi.org/10.1016/j.jaip.2021.04.035

ALLIANCE Study Group, Abdo, M, Waschki, B, Trinkmann, F, Biller, H, Herzmann, C, von Mutius, E, Kopp, M, Hansen, G, Rabe, KF, Bahmer, T & Watz, H 2021, 'Persistent Uncontrolled Asthma: Long-Term Impact on Physical Activity and Body Composition', Journal of Asthma and Allergy, Jg. 14, S. 229-240. https://doi.org/10.2147/JAA.S299756

Chesov, D, Heyckendorf, J, Alexandru, S, Donica, A, Chesov, E, Reiman, M, Crudu, V, Botnaru, V & Lange, C 2021, 'Impact of bedaquiline on treatment outcomes of multidrug-resistant tuberculosis in a high-burden country', The European respiratory journal, Jg. 57, Nr. 6, 2002544. https://doi.org/10.1183/13993003.02544-2020

Chesov, E, Chesov, D, Maurer, FP, Andres, S, Utpatel, C, Barilar, I, Donica, A, Reimann, M, Niemann, S, Lange, C, Crudu, V, Heyckendorf, J & Merker, M 2021, 'Emergence of bedaquiline-resistance in a high-burden country of tuberculosis', The European respiratory journal. https://doi.org/10.1183/13993003.00621-2021

COVID-19 Aachen Study (COVAS) 2021, 'Swarm Learning for decentralized and confidential clinical machine learning', NATURE, Jg. 594, Nr. 7862, S. 265-270. https://doi.org/10.1038/s41586-021-03583-3

COVID-19 Host Genetics Initiative, Lange, C, Heyckendorf, J & Gaede, KI 2021, 'Mapping the human genetic architecture of COVID-19', NATURE. https://doi.org/10.1038/s41586-021-03767-x

DiNardo, AR, Nishiguchi, T, Grimm, SL, Schlesinger, LS, Graviss, EA, Cirillo, JD, Coarfa, C, Mandalakas, AM, Heyckendorf, J, Kaufmann, SHE, Lange, C, Netea, MG & Van Crevel, R 2021, 'Tuberculosis endotypes to guide stratified host-directed therapy', Med (New York, N.Y.), Jg. 2, Nr. 3, S. 217-232. https://doi.org/10.1016/j.medj.2020.11.003

DZIF-TB cohort study group, Heyckendorf, J, Reimann, M, Marwitz, S & Lange, C 2021, 'Pathogen-free diagnosis of tuberculosis', Lancet Infectious Diseases, Jg. 21, Nr. 8, S. 1066. https://doi.org/10.1016/S1473-3099(21)00337-6

Freundt, K, Herzmann, C, Biedziak, D, Scheffzük, C, Gaede, KI & Stamme, C 2021, 'Surfactant protein A enhances the degradation of LPS-induced TLR4 in primary alveolar macrophages involving Rab7, β-arrestin2, and mTORC1', INFECTION AND IMMUNITY , S. IAI0025021. https://doi.org/10.1128/IAI.00250-21

Grobbel, H-P, Merker, M, Köhler, N, Andres, S, Hoffmann, H, Heyckendorf, J, Reimann, M, Barilar, I, Dreyer, V, Hillemann, D, Kalsdorf, B, Kohl, TA, Sanchez-Carballo, P, Schaub, D, Todt, K, Utpatel, C, Maurer, FP, Lange, C & Niemann, S 2021, 'Design of multidrug-resistant tuberculosis treatment regimens based on DNA sequencing', CLINICAL INFECTIOUS DISEASES , Jg. 73, Nr. 7, S. 1194-1202. https://doi.org/10.1093/cid/ciab359

Kontsevaya, I, Lange, C, Comella-Del-Barrio, P, Coarfa, C, DiNardo, AR, Gillespie, SH, Hauptmann, M, Leschczyk, C, Mandalakas, AM, Martinecz, A, Merker, M, Niemann, S, Reimann, M, Rzhepishevska, O, Schaible, UE, Scheu, KM, Schurr, E, Abel Zur Wiesch, P & Heyckendorf, J 2021, 'Perspectives for systems biology in the management of tuberculosis', European Respiratory Review, Jg. 30, Nr. 160. https://doi.org/10.1183/16000617.0377-2020

Pfeuffer-Jovic, E, Heyckendorf, J, Reischl, U, Bohle, RM, Bley, T, Buck, A, Wilkens, H, Schäfers, H-J, Langen, H-J & Held, M 2021, 'Pulmonary vasculitis due to infection with Mycobacterium goodii: a case report', INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES , Jg. 104, S. 178-180. https://doi.org/10.1016/j.ijid.2020.12.074

 

2020

Andres, S, Merker, M, Heyckendorf, J, Kalsdorf, B, Rumetshofer, R, Indra, A, Hofmann-Thiel, S, Hoffmann, H, Lange, C, Niemann, S & Maurer, FP 2020, 'Bedaquiline-resistant Tuberculosis: Dark Clouds on the Horizon', American journal of respiratory and critical care medicine. https://doi.org/10.1164/rccm.201909-1819LE

Butov, D, Lange, C, Heyckendorf, J, Kalmykova, I, Butova, T, Borovok, N, Novokhatskaya, M & Chesov, D 2020, 'Multidrug-resistant tuberculosis in the Kharkiv Region, Ukraine', INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Jg. 24, Nr. 5, S. 485-491. https://doi.org/10.5588/ijtld.19.0508

Eggeling, J, Heyckendorf, J, Lange, C, Maier, C, Reimann, M, Sassmann-Schweda, A, Shaikh, R, Herzmann, C & Luethgen, M 2020, 'Changes in taste and smell as an early marker for COVID-19', INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES , Jg. 99, S. 8-9. https://doi.org/10.1016/j.ijid.2020.07.018

Jünger, C, Reimann, M, Krabbe, L, Gaede, KI, Lange, C, Herzmann, C & Rüller, S 2020, 'Non-invasive ventilation with pursed lips breathing mode for patients with COPD and hypercapnic respiratory failure: A retrospective analysis', PLOS ONE, Jg. 15, Nr. 9, S. e0238619. https://doi.org/10.1371/journal.pone.0238619

Lange, C, Aarnoutse, R, Chesov, D, van Crevel, R, Gillespie, SH, Grobbel, H-P, Kalsdorf, B, Kontsevaya, I, van Laarhoven, A, Nishiguchi, T, Mandalakas, A, Merker, M, Niemann, S, Köhler, N, Heyckendorf, J, Reimann, M, Ruhwald, M, Sanchez-Carballo, P, Schwudke, D, Waldow, F & DiNardo, AR 2020, 'Perspective for Precision Medicine for Tuberculosis', FRONTIERS IN IMMUNOLOGY, Jg. 11, S. 566608. https://doi.org/10.3389/fimmu.2020.566608

Suárez, I, Gruell, H, Heyckendorf, J, Fünger, S, Lichtenstein, T, Jung, N, Lehmann, C, Unnewehr, M, Fätkenheuer, G, Lange, C & Rybniker, J 2020, 'Intensified adjunctive corticosteroid therapy for CNS tuberculomas', Infection. https://doi.org/10.1007/s15010-019-01378-3

WILLOW Investigators & Herzmann, C 2020, 'Phase 2 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis', New England Journal of Medicine. https://doi.org/10.1056/NEJMoa2021713

 

2019

Webering, S, Lunding, LP, Vock, C, Schröder, A, Gaede, KI, Herzmann, C, Fehrenbach, H & Wegmann, M 2019, 'The alpha-melanocyte-stimulating hormone acts as a local immune homeostasis factor in experimental allergic asthma', Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, Jg. 49, Nr. 7, S. 1026-1039. https://doi.org/10.1111/cea.13400

 

2018

ATLANTIC Investigators & Herzmann, C 2018, 'Durvalumab as third-line or later treatment for advanced non-small-cell lung cancer (ATLANTIC): an open-label, single-arm, phase 2 study' Lancet Oncology, Jg. 19, Nr. 4, S. 521-536.

Silkoff, PE, Flavin, S, Gordon, R, Loza, MJ, Sterk, PJ, Lutter, R, Diamant, Z, Turner, RB, Lipworth, BJ, Proud, D, Singh, D, Eich, A, Backer, V, Gern, JE, Herzmann, C, Halperin, SA, Mensinga, TT, Del Vecchio, AM, Branigan, P, San Mateo, L, Baribaud, F, Barnathan, ES & Johnston, SL 2018, 'TLR3 Blockade in Rhinovirus-Induced Experimental Asthma Exacerbations: A Randomized Controlled Study' The Journal of allergy and clinical immunology. https://doi.org/10.1016/j.jaci.2017.06.027

Convert Study Group, Herzmann, C, Griffith, DE & Winthrop, KL 2018, 'Amikacin Liposome Inhalation Suspension for Treatment-Refractory Lung Disease Caused by Mycobacterium avium Complex (CONVERT): A Prospective, Open-Label, Randomized Study.' American journal of respiratory and critical care medicine. https://doi.org/10.1164/rccm.201807-1318OC

Salzer, HJF, Prattes, J, Flick, H, Reimann, M, Heyckendorf, J, Kalsdorf, B, Obersteiner, S, Gaede, KI, Herzmann, C, Johnson, GL, Lange, C & Hoenigl, M 2018, 'Evaluation of Galactomannan Testing, the Aspergillus-Specific Lateral-Flow Device Test and Levels of Cytokines in Bronchoalveolar Lavage Fluid for Diagnosis of Chronic Pulmonary Aspergillosis' Frontiers in Microbiology, Jg. 9, S. 2223.

IMPULSE study team & Herzmann, C 2018, 'Immunotherapeutic maintenance treatment with toll-like receptor 9 agonist lefitolimod in patients with extensive-stage small-cell lung cancer: results from the exploratory, controlled, randomized, international phase II IMPULSE study' Annals of oncology : official journal of the European Society for Medical Oncology / ESMO, Jg. 29, Nr. 10, S. 2076-2084.

Herzmann, C, Dallenga, T & Kalinke, U 2018, 'Pulmonale Immunität bei Tuberkulose' PNEUMOLOGIE, Jg. 72, S. 1-10.

Herzmann, C, Lange, C & Günther, G 2018, Tuberkulose (TB). in C Hoffmann & J Rockstroh (Hrsg.), HIV Buch 2018/2019. Medizin Fokus Verlag, Hamburg, S. 340-351.

 

2017

Herzmann, C, Ernst, M, Lange, C, Stenger, S, Kaufmann, SHE, Reiling, N, Schaberg, T, van der Merwe, L, Maertzdorf, J & Tb or not Tb consortium 2017, 'Pulmonary immune responses to Mycobacterium tuberculosis in exposed individuals' PLOS ONE, Bd 12, Nr. 11, S. e0187882. DOI: 10.1371/journal.pone.0187882

Bahmer, T, Waschki, B, Schatz, F, Herzmann, C, Zabel, P, Kirsten, A-M, Rabe, KF, Watz, H & ERA-Study Group 2017, 'Physical activity, airway resistance and small airway dysfunction in severe asthma' The European respiratory journal, Bd 49, Nr. 1, S. pii 1601827. DOI: 10.1183/13993003.01827-2016

Herzmann, C, Golakov, M, Malekzada, F, Lonnroth, K & Kranzer, K 2017, 'Radiological screening of refugees in Germany' The European respiratory journal, Bd 49, Nr. 5. DOI: 10.1183/13993003.02487-2016

Labugger, I, Heyckendorf, J, Dees, S, Häussinger, E, Herzmann, C, Kohl, TA, Richter, E, Rivera-Milla, E & Lange, C 2017, 'Detection of transrenal DNA for the diagnosis of pulmonary tuberculosis and treatment monitoring' INFECTION, Bd 45, Nr. 3, S. 269-276. DOI: 10.1007/s15010-016-0955-2

Nakiwala, D, Kellgren, L, Herzmann, C, Olaru, ID, Brown, M, Ferrand, RA, Khan, P & Kranzer, K 2017, 'Language discordance between tuberculosis patients and healthcare providers challenging universal access' The European respiratory journal, Bd 49, Nr. 4. DOI: 10.1183/13993003.00116-2017

Silkoff, PE, Flavin, S, Gordon, R, Loza, MJ, Sterk, PJ, Lutter, R, Diamant, Z, Turner, RB, Lipworth, BJ, Proud, D, Singh, D, Eich, A, Backer, V, Gern, JE, Herzmann, C, Halperin, SA, Mensinga, TT, Del Vecchio, AM, Branigan, P, San Mateo, L, Baribaud, F, Barnathan, ES & Johnston, SL 2017, 'TLR3 Blockade in Rhinovirus-Induced Experimental Asthma Exacerbations: A Randomized Controlled Study' The Journal of allergy and clinical immunology. DOI: 10.1016/j.jaci.2017.06.027