Medicine

Pathology of the University Hospital Schleswig-Holstein, Campus Lübeck and the Leibniz Research Center Borstel
location Borstel

Pathology

Mission    Projects     Funding     Techniques    Publications    
Krankenversorgung     Diagnostik     Konsil- und Referenzzentrum für Pulmopathologie    Einsender    
Staff

Publications

2021

Ellebrecht, DB, Kuempers, C, Perner, S, Kugler, C & Kleemann, M 2021, 'Confocal laser microscopy without fluorescent dye in minimal-invasive thoracic surgery: an ex-vivo pilot study in lung cancer', Biomedizinische Technik. Biomedical engineering, Jg. 66, Nr. 3, S. 285-292. https://doi.org/10.1515/bmt-2020-0162

Glöckner, M, Marwitz, S, Rohmann, K, Watz, H, Nitschkowski, D, Rupp, J, Dalhoff, K, Goldmann, T & Drömann, D 2021, 'Haemophilus influenzae causes cellular trans-differentiation in human bronchial epithelia', INNATE IMMUNITY, Jg. 27, Nr. 3, S. 251-259. https://doi.org/10.1177/1753425921994906

Goldmann, T, Schmitt, B, Müller, J, Kröger, M, Scheufele, S, Marwitz, S, Nitschkowski, D, Schneider, MA, Meister, M, Muley, T, Thomas, M, Kugler, C, Rabe, KF, Siebert, R, Reck, M & Ammerpohl, O 2021, 'DNA methylation profiles of bronchoscopic biopsies for the diagnosis of lung cancer', Clinical epigenetics, Jg. 13, Nr. 1, S. 38. https://doi.org/10.1186/s13148-021-01024-6

Goldmann, T, Hillemann, D, Maurer, F, Kalsdorf, B, Krupar, R, Stellmacher, F & Perner, S 2021, 'Mycobacterium szulgai als Posititivkontrolle zur Detektion von Kontaminationen beim Nachweis des Mycobacterium tuberculosis-Komplexes durch eine spezifische 16S-rDNA-PCR an FFPE-Material', Der Pathologe, Jg. 42, Nr. 1, S. 83-85. https://doi.org/10.1007/s00292-021-00912-1

Krupar, R, Kümpers, C, Haenel, A, Perner, S & Stellmacher, F 2021, 'Kryptogen organisierende Pneumonie versus sekundäre organisierende Pneumonie', Der Pathologe, Jg. 42, Nr. 1, S. 55-63. https://doi.org/10.1007/s00292-020-00903-8

Marwitz, S, Ballesteros-Merino, C, Jensen, SM, Reck, M, Kugler, C, Perner, S, Drömann, D, Goldmann, T & Fox, BA 2021, 'Phosphorylation of SMAD3 in immune cells predicts survival of patients with early stage non-small cell lung cancer', Journal for Immunotherapy of Cancer, Jg. 9, Nr. 2. https://doi.org/10.1136/jitc-2020-001469

Merseburger, AS, Waldron, N, Ribal, MJ, Heidenreich, A, Perner, S, Fizazi, K, Sternberg, CN, Mateo, J, Wirth, MP, Castro, E, Olmos, D, Petrylak, DP & Chowdhury, S 2021, 'Genomic Testing in Patients with Metastatic Castration-resistant Prostate Cancer: A Pragmatic Guide for Clinicians', European Urology, Jg. 79, Nr. 4, S. 519-529. https://doi.org/10.1016/j.eururo.2020.12.039

Pasternack, H, Kuempers, C, Deng, M, Watermann, I, Olchers, T, Kuehnel, M, Jonigk, D, Kugler, C, Stellmacher, F, Goldmann, T, Kirfel, J, Ammerpohl, O, Perner, S & Reck, M 2021, 'Identification of molecular signatures associated with early relapse after complete resection of lung adenocarcinomas', Scientific Reports, Jg. 11, Nr. 1, S. 9532. https://doi.org/10.1038/s41598-021-89030-9

Rades, D, Staackmann, C, Ribbat-Idel, J, Perner, S, Idel, C, Bruchhage, KL, Hakim, SG & Schild, SE 2021, 'A New Survival Score for Patients Scheduled for Palliative Irradiation of Locally Advanced Carcinoma of the Head-and-Neck', Anticancer research, Jg. 41, Nr. 6, S. 3055-3058. https://doi.org/10.21873/anticanres.15088

Ribbat-Idel, J, Perner, S, Kuppler, P, Klapper, L, Krupar, R, Watermann, C, Paulsen, F-O, Offermann, A, Bruchhage, K-L, Wollenberg, B & Idel, C 2021, 'Immunologic "Cold" Squamous Cell Carcinomas of the Head and Neck Are Associated With an Unfavorable Prognosis', Frontiers in Medicine, Jg. 8, S. 622330. https://doi.org/10.3389/fmed.2021.622330

Ribbat-Idel, J, Dressler, FF, Krupar, R, Watermann, C, Paulsen, F-O, Kuppler, P, Klapper, L, Offermann, A, Wollenberg, B, Rades, D, Laban, S, Reischl, M, Bruchhage, K-L, Idel, C & Perner, S 2021, 'Performance of Different Diagnostic PD-L1 Clones in Head and Neck Squamous Cell Carcinoma', Frontiers in Medicine, Jg. 8, S. 640515. https://doi.org/10.3389/fmed.2021.640515

Roessler, FC, Kalms, N, Jann, F, Kemmling, A, Ribbat-Idel, J, Stellmacher, F, König, IR, Ohlrich, M & Royl, G 2021, 'First approach to distinguish between cardiac and arteriosclerotic emboli of individual stroke patients applying the histological THROMBEX-classification rule', Scientific Reports, Jg. 11, Nr. 1, S. 8433. https://doi.org/10.1038/s41598-021-87584-2

Staackmann, C, Ribbat-Idel, J, Perner, S, Idel, C, Bruchhage, KL, Hakim, SG, Schild, SE & Rades, D 2021, 'Palliative Local Radiotherapy for Advanced Squamous Cell Carcinoma of the Head-and-Neck: Prognostic Factors of Survival', Anticancer research, Jg. 41, Nr. 6, S. 3205-3210. https://doi.org/10.21873/anticanres.15107

Stellmacher, F & Perner, S 2021, 'Histopathologie der Lungentuberkulose', Der Pathologe, Jg. 42, Nr. 1, S. 71-77. https://doi.org/10.1007/s00292-021-00910-3

Stellmacher, F, Kirfel, J, Kalsdorf, B, Maurer, FP, Perner, S & Goldmann, T 2021, 'Molekularpathologie der Tuberkulose: Stellenwert, Methodik und Grenzen', Der Pathologe, Jg. 42, Nr. 1, S. 78-82. https://doi.org/10.1007/s00292-021-00911-2

Stellmacher, F & Perner, S 2021, 'Übersicht: Granulomatöse Erkrankungen der Lunge', Der Pathologe, Jg. 42, Nr. 1, S. 64-70. https://doi.org/10.1007/s00292-020-00893-7

Struck, JP, Kramer, MW, Katzendorn, O, Hupe, MC, Ozimek, T, Hennig, MJP, Wießmeyer, JR, von Klot, CAJ, Kuczyk, MA, Kreipe, HH, Merseburger, AS, Perner, S & Dressler, FF 2021, 'Bicentric Retrospective Analysis of en Bloc Resection and Muscularis Mucosae Detection Rate in Non-Muscle Invasive Bladder Tumors: A Real-World Scenario', Advances in therapy, Jg. 38, Nr. 1, S. 258-267. https://doi.org/10.1007/s12325-020-01529-1

Sünderhauf, A, Hicken, M, Schlichting, H, Skibbe, K, Ragab, M, Raschdorf, A, Hirose, M, Schäffler, H, Bokemeyer, A, Bettenworth, D, Savitt, AG, Perner, S, Ibrahim, S, Peerschke, EL, Ghebrehiwet, B, Derer, S & Sina, C 2021, 'Loss of Mucosal p32/gC1qR/HABP1 Triggers Energy Deficiency and Impairs Goblet Cell Differentiation in Ulcerative Colitis', Cellular and molecular gastroenterology and hepatology, Jg. 12, Nr. 1, S. 229-250. https://doi.org/10.1016/j.jcmgh.2021.01.017

Watermann, C, Pasternack, H, Idel, C, Ribbat-Idel, J, Brägelmann, J, Kuppler, P, Offermann, A, Jonigk, D, Kühnel, M, Schröck, A, Dreyer, E, Rosero, C, Nathansen, J, Dubrovska, A, Tharun, L, Kirfel, J, Wollenberg, B, Perner, S & Krupar, R 2021, 'Recurrent HNSCC harbor an immunosuppressive tumor immune microenvironment suggesting successful tumor immune evasion', CLINICAL CANCER RESEARCH , Jg. 27, Nr. 2, S. 632-644. https://doi.org/10.1158/1078-0432.CCR-20-0197

 

2020

Becker, F, Joerg, V, Hupe, MC, Roth, D, Krupar, R, Lubczyk, V, Kuefer, R, Sailer, V, Duensing, S, Kirfel, J, Merseburger, AS, Brägelmann, J, Perner, S & Offermann, A 2020, 'Increased Mediator complex subunit CDK19 expression associates with aggressive prostate cancer', INTERNATIONAL JOURNAL OF CANCER , Jg. 146, Nr. 2, S. 577-588. https://doi.org/10.1002/ijc.32551

Franzen, KF, Belkin, S, Goldmann, T, Reppel, M, Watz, H, Mortensen, K & Droemann, D 2020, 'The impact of heated tobacco products on arterial stiffness', Vascular medicine (London, England), S. 1358863X20943292. https://doi.org/10.1177/1358863X20943292

Groth, EE, Weber, M, Bahmer, T, Pedersen, F, Kirsten, A, Börnigen, D, Rabe, KF, Watz, H, Ammerpohl, O & Goldmann, T 2020, 'Exploration of the sputum methylome and omics deconvolution by quadratic programming in molecular profiling of asthma and COPD: the road to sputum omics 2.0', RESPIRATORY RESEARCH , Jg. 21, Nr. 1, S. 274. https://doi.org/10.1186/s12931-020-01544-4

Hennenlotter, J, Neumann, T, Perner, S, Wagner, V, Stenzl, A, Todenhöfer, T & Rausch, S 2020, 'Impact of Histopathological Prostate Inflammation on Urine-Based Prostate Cancer Prediction Using the Prostate Cancer Gene 3 Score', Urologia internationalis, Jg. 104, Nr. 5-6, S. 483-488. https://doi.org/10.1159/000506885

Hupe, MC, Offermann, A, Tharun, L, Fürschke, A, Frydrychowicz, A, Garstka, N, Shariat, SF, Barkhausen, J, Merseburger, AS, Kramer, MW & Perner, S 2020, 'Histomorphological analysis of false positive PI-RADS 4 and 5 lesions', Urologic oncology, Jg. 38, Nr. 7, S. 636.e7-636.e12. https://doi.org/10.1016/j.urolonc.2020.01.017

Idel, C, Ribbat-Idel, J, Kuppler, P, Krupar, R, Offermann, A, Vogel, W, Rades, D, Kirfel, J, Wollenberg, B & Perner, S 2020, 'EVI1 as a Marker for Lymph Node Metastasis in HNSCC', INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , Jg. 21, Nr. 3. https://doi.org/10.3390/ijms21030854

Klapper, L, Ribbat-Idel, J, Kuppler, P, Paulsen, F-O, Bruchhage, K-L, Rades, D, Offermann, A, Kirfel, J, Wollenberg, B, Idel, C & Perner, S 2020, 'NR2F6 as a Prognostic Biomarker in HNSCC', INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , Jg. 21, Nr. 15. https://doi.org/10.3390/ijms21155527

Krupar, R, Watermann, C, Idel, C, Ribbat-Idel, J, Offermann, A, Pasternack, H, Kirfel, J, Sikora, AG & Perner, S 2020, 'In silico analysis reveals EP300 as a panCancer inhibitor of anti-tumor immune response via metabolic modulation', Scientific Reports, Jg. 10, Nr. 1, S. 9389. https://doi.org/10.1038/s41598-020-66329-7

Kuempers, C, van der Linde, LIS, Reischl, M, Vogel, W, Stellmacher, F, Reck, M, Heigener, D, Rabe, KF, Kirfel, J, Perner, S & Welker, L 2020, 'Comparison of PD-L1 expression between paired cytologic and histologic specimens from non-small cell lung cancer patients', Virchows Archiv : an international journal of pathology, Jg. 476, Nr. 2, S. 261-271. https://doi.org/10.1007/s00428-019-02632-7

Liu, X, Tufman, A, Behr, J, Kiefl, R, Goldmann, T & Huber, RM 2020, 'Role of the erythropoietin receptor in Lung Cancer cells: erythropoietin exhibits angiogenic potential', Journal of Cancer, Jg. 11, Nr. 20, S. 6090-6100. https://doi.org/10.7150/jca.36924

Marwitz, S, Turkowski, K, Nitschkowski, D, Weigert, A, Brandenburg, J, Reiling, N, Thomas, M, Reck, M, Drömann, D, Seeger, W, Rabe, KF, Savai, R & Goldmann, T 2020, 'The Multi-Modal Effect of the Anti-fibrotic Drug Pirfenidone on NSCLC', Frontiers in Oncology, Jg. 9, S. 1550. https://doi.org/10.3389/fonc.2019.01550

Offermann, A, Hupe, MC, Joerg, V, Sailer, V, Kramer, MW, Merseburger, AS, Tharun, L & Perner, S 2020, 'Befundbericht zu Prostatastanzbiopsien – was Pathologen liefern und Urologen wollen', Der Urologe. Ausg. A, Jg. 59, Nr. 4, S. 461-468. https://doi.org/10.1007/s00120-020-01121-z

Paulsen, F-O, Idel, C, Ribbat-Idel, J, Kuppler, P, Klapper, L, Rades, D, Bruchhage, K-L, Wollenberg, B, Brägelmann, J, Perner, S & Offermann, A 2020, 'CDK19 as a Potential HPV-Independent Biomarker for Recurrent Disease in HNSCC', INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , Jg. 21, Nr. 15. https://doi.org/10.3390/ijms21155508

Petrova, E, Zielinski, V, Bolm, L, Schreiber, C, Knief, J, Thorns, C, Bronsert, P, Timme-Bronsert, S, Bausch, D, Perner, S, Keck, T & Wellner, U 2020, 'Tumor budding as a prognostic factor in pancreatic ductal adenocarcinoma', Virchows Archiv : an international journal of pathology, Jg. 476, Nr. 4, S. 561-568. https://doi.org/10.1007/s00428-019-02719-1

Sünderhauf, A, Raschdorf, A, Hicken, M, Schlichting, H, Fetzer, F, Brethack, A-K, Perner, S, Kemper, C, Ghebrehiwet, B, Sina, C & Derer, S 2020, 'GC1qR Cleavage by Caspase-1 Drives Aerobic Glycolysis in Tumor Cells', Frontiers in Oncology, Jg. 10, S. 575854. https://doi.org/10.3389/fonc.2020.575854

Thunnissen, E, Weynand, B, Udovicic-Gagula, D, Brcic, L, Szolkowska, M, Hofman, P, Smojver-Ježek, S, Anttila, S, Calabrese, F, Kern, I, Skov, B, Perner, S, Dale, VG, Eri, Z, Haragan, A, Leonte, D, Carvallo, L, Prince, SS, Nicholson, S, Sansano, I & Ryska, A 2020, 'Lung cancer biomarker testing: perspective from Europe', Translational lung cancer research, Jg. 9, Nr. 3, S. 887-897. https://doi.org/10.21037/tlcr.2020.04.07

2019

Correa, W, Brandenburg, J, Behrends, J, Heinbockel, L, Reiling, N, Paulowski, L, Schwudke, D, Stephan, K, Martinez-de-Tejada, G, Brandenburg, K & Gutsmann, T 2019, 'Inactivation of Bacteria by γ-Irradiation to Investigate the Interaction with Antimicrobial Peptides', Biophysical journal, Jg. 117, Nr. 10, S. 1805-1819. https://doi.org/10.1016/j.bpj.2019.10.012

Fischer, AK, Pham, DL, Bösmüller, H, Lengerke, C, Wagner, P, Bachmann, C, Beschorner, C, Perner, S, Kommoss, S, Fend, F & Staebler, A 2019, 'Comprehensive in situ analysis of ALDH1 and SOX2 reveals increased expression of stem cell markers in high-grade serous carcinomas compared to low-grade serous carcinomas and atypical proliferative serous tumors', Virchows Archiv : an international journal of pathology, Jg. 475, Nr. 4, S. 479-488. https://doi.org/10.1007/s00428-019-02647-0

Gaisa, NT, Kristiansen, G & Perner, S 2019, 'Molekulares Tumorboard Uroonkologie aus pathologischer Sicht', Der Urologe. Ausg. A, Jg. 58, Nr. 7, S. 747-751. https://doi.org/10.1007/s00120-019-0934-1

Hupe, MC, Hoda, MR, Zengerling, F, Perner, S, Merseburger, AS & Cronauer, MV 2019, 'The BET-inhibitor PFI-1 diminishes AR/AR-V7 signaling in prostate cancer cells', World journal of Urology, Jg. 37, Nr. 2, S. 343-349. https://doi.org/10.1007/s00345-018-2382-8

Hupe, MC, Offermann, A, Sailer, V, Merseburger, AS & Perner, S 2019, 'Das neue ISUP 2014/WHO 2016 Prostatakarzinom-Grading – Status quo 5 Jahre nach seiner Einführung', Aktuelle Urologie, Jg. 50, Nr. 6, S. 619-624. https://doi.org/10.1055/a-0918-9473

Kümpers, C, Jokic, M, Haase, O, Offermann, A, Vogel, W, Grätz, V, Langan, EA, Perner, S & Terheyden, P 2019, 'Immune Cell Infiltration of the Primary Tumor, Not PD-L1 Status, Is Associated With Improved Response to Checkpoint Inhibition in Metastatic Melanoma', Frontiers in Medicine, Jg. 6, S. 27. https://doi.org/10.3389/fmed.2019.00027

Langan, EA, Kümpers, C, Graetz, V, Perner, S, Zillikens, D & Terheyden, P 2019, 'Intralesional interleukin-2: A novel option to maximize response to systemic immune checkpoint therapy in loco-regional metastatic melanoma', Dermatologic therapy, Jg. 32, Nr. 3, S. e12901. https://doi.org/10.1111/dth.12901

Lilis, I, Ntaliarda, G, Papaleonidopoulos, V, Giotopoulou, GA, Oplopoiou, M, Marazioti, A, Spella, M, Marwitz, S, Goldmann, T, Bravou, V, Giopanou, I & Stathopoulos, GT 2019, 'Interleukin-1β provided by KIT-competent mast cells is required for KRAS-mutant lung adenocarcinoma', OncoImmunology, Jg. 8, Nr. 7, S. 1593802. https://doi.org/10.1080/2162402X.2019.1593802

Metzger, E, Wang, S, Urban, S, Willmann, D, Schmidt, A, Offermann, A, Allen, A, Sum, M, Obier, N, Cottard, F, Ulferts, S, Preca, B-T, Hermann, B, Maurer, J, Greschik, H, Hornung, V, Einsle, O, Perner, S, Imhof, A, Jung, M & Schüle, R 2019, 'KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells', Nature structural & molecular biology, Jg. 26, Nr. 5, S. 361-371. https://doi.org/10.1038/s41594-019-0219-9

Nitschkowski, D, Marwitz, S, Kotanidou, SA, Reck, M, Kugler, C, Rabe, KF, Ammerpohl, O & Goldmann, T 2019, 'Live and let die: epigenetic modifications of Survivin and Regucalcin in non-small cell lung cancer tissues contribute to malignancy', Clinical epigenetics, Jg. 11, Nr. 1, S. 157. https://doi.org/10.1186/s13148-019-0770-6

Offermann, A, Hupe, MC, Sailer, V, Merseburger, AS & Perner, S 2019, 'The new ISUP 2014/WHO 2016 prostate cancer grade group system: first résumé 5 years after introduction and systemic review of the literature', World journal of Urology, S. 1-6. https://doi.org/10.1007/s00345-019-02744-4

Offermann, A, Roth, D, Hupe, MC, Hohensteiner, S, Becker, F, Joerg, V, Carlsson, J, Kuempers, C, Ribbat-Idel, J, Tharun, L, Sailer, V, Kirfel, J, Svensson, M, Andren, O, Lubczyk, V, Kuefer, R, Merseburger, AS & Perner, S 2019, 'TRIM24 as an independent prognostic biomarker for prostate cancer', Urologic oncology, Jg. 37, Nr. 9, S. 576.e1-576.e10. https://doi.org/10.1016/j.urolonc.2019.05.006

Ortiz-Brüchle, N, Muders, M, Toma, M, Esposito, I, Hartmann, A, Stöhr, R, Reis, H, Wild, P, Köllermann, J, Bremmer, F, Leichsenring, J, Stenzinger, A, Merkelbach-Bruse, S, Kirfel, S, Perner, S, Hartmann, N, Roth, W, Jung, A, Kirchner, T, Schwamborn, K, Pfarr, N, Dahl, E, Knüchel, R & Gaisa, NT 2019, 'Status der Verfügbarkeit und Anwendung von „next generation sequencing“ (NGS) beim Harnblasenkarzinom – eine Umfrage in der Arbeitsgemeinschaft Uropathologie', Der Urologe. Ausg. A, S. 1-8. https://doi.org/10.1007/s00120-019-01046-2

Perner, S 2019, 'Bericht zur Sitzung der AG Kopf-Hals-Pathologie: 103. Jahrestagung der Deutschen Gesellschaft für Pathologie in Frankfurt am Main am 13.06.2019', Der Pathologe, Jg. 40, Nr. Suppl 3, S. 392. https://doi.org/10.1007/s00292-019-00646-1

Petrova, E, Zielinski, V, Bolm, L, Schreiber, C, Knief, J, Thorns, C, Bronsert, P, Timme-Bronsert, S, Bausch, D, Perner, S, Keck, T & Wellner, U 2019, 'Tumor budding as a prognostic factor in pancreatic ductal adenocarcinoma', Virchows Archiv : an international journal of pathology. https://doi.org/10.1007/s00428-019-02719-1

Pfalzgraff, A, Correa, W, Heinbockel, L, Schromm, AB, Lübow, C, Gisch, N, Martinez-de-Tejada, G, Brandenburg, K & Weindl, G 2019, 'LPS-neutralizing peptides reduce outer membrane vesicle-induced inflammatory responses', BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, Jg. 1864, Nr. 10, S. 1503-1513. https://doi.org/10.1016/j.bbalip.2019.05.018

Rades, D, Narvaez, CA, Splettstößer, L, Dömer, C, Setter, C, Idel, C, Ribbat-Idel, J, Perner, S, Bartscht, T, Olbrich, D, Schild, SE & Carl, J 2019, 'A randomized trial (RAREST-01) comparing Mepitel® Film and standard care for prevention of radiation dermatitis in patients irradiated for locally advanced squamous cell carcinoma of the head-and-neck (SCCHN)', Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, Jg. 139, S. 79-82. https://doi.org/10.1016/j.radonc.2019.07.023

Riabinska, A, Lehrmann, D, Jachimowicz, RD, Knittel, G, Fritz, C, Schmitt, A, Geyer, A, Heneweer, C, Wittersheim, M, Frenzel, LP, Torgovnick, A, Wiederstein, JL, Wunderlich, CM, Ortmann, M, Paillard, A, Wößmann, W, Borkhardt, A, Burdach, S, Hansmann, M-L, Rosenwald, A, Perner, S, Mall, G, Klapper, W, Merseburg, A, Krüger, M, Grüll, H, Persigehl, T, Wunderlich, FT, Peifer, M, Utermöhlen, O, Büttner, R, Beleggia, F & Reinhardt, HC 2019, 'ATM activity in T cells is critical for immune surveillance of lymphoma in vivo', LEUKEMIA. https://doi.org/10.1038/s41375-019-0618-2

 

2018

Capper, D, Engel, NW, Stichel, D, Lechner, M, Glöss, S, Schmid, S, Koelsche, C, Schrimpf, D, Niesen, J, Wefers, AK, Jones, DTW, Sill, M, Weigert, O, Ligon, KL, Olar, A, Koch, A, Forster, M, Moran, S, Tirado, OM, Sáinz-Japeado, M, Mora, J, Esteller, M, Alonso, J, Del Muro, XG, Paulus, W, Felsberg, J, Reifenberger, G, Glatzel, M, Frank, S, Monoranu, CM, Lund, VJ, von Deimling, A, Pfister, S, Buslei, R, Ribbat-Idel, J, Perner, S, Gudziol, V, Meinhardt, M & Schüller, U 2018, 'DNA methylation-based reclassification of olfactory neuroblastoma' Acta neuropathologica, Jg. 136, Nr. 2, S. 255-271. DOI: 10.1007/s00401-018-1854-7

Zhang, Y, Wang, X, Perner, S, Bánkfalvi, Á & Schlücker, S 2018, 'Effect of antigen retrieval methods on non-specific binding of anti-body-metal nanoparticle conjugates on FFPE tissue' ANALYTICAL CHEMISTRY , Jg. 10, S. 11. DOI: 10.1021/acs.analchem.7b03144

Tamò, L, Simillion, C, Hibaoui, Y, Feki, A, Gugger, M, Prasse, A, Jäger, B, Goldmann, T, Geiser, T & Gazdhar, A 2018, 'Gene Network Analysis of Interstitial Macrophages After Treatment with Induced Pluripotent Stem Cells Secretome (iPSC-cm) in the Bleomycin Injured Rat Lung' Stem cell reviews, Jg. 14, Nr. 3, S. 412-424. DOI: 10.1007/s12015-017-9790-9

Krupar, R, Hautmann, MG, Pathak, RR, Varier, I, McLaren, C, Gaag, D, Hellerbrand, C, Evert, M, Laban, S, Idel, C, Sandulache, V, Perner, S, Bosserhoff, AK & Sikora, AG 2018, 'Immuno-metabolic determinants of chemoradiotherapy response and survival in head and neck squamous cell carcinoma' AMERICAN JOURNAL OF PATHOLOGY, Jg. 188, Nr. 1, S. 72-83. DOI: 10.1016/j.ajpath.2017.09.013

Hupe, MC, Offermann, A, Perabo, F, Chandhasin, C, Perner, S, Merseburger, AS & Cronauer, MV 2018, 'Inhibitoren des Androgenrezeptor-N-Terminus’: Zielgerichtete Therapien gegen die Achillesferse verschiedener Androgenrezeptormoleküle im fortgeschrittenen Prostatakarzinom' Der Urologe. Ausg. A, Jg. 57, Nr. 2, S. 148-154. DOI: 10.1007/s00120-017-0541-y

Krupar, R, Schreiber, C, Offermann, A, Lengerke, C, Sikora, AG, Thorns, C & Perner, S 2018, 'In silico analysis of anti-leukemia immune response and immune evasion in acute myeloid leukemia' Leukemia & lymphoma, Jg. 12, S. 1-4. DOI: 10.1080/10428194.2018.1434883

George, J, Walter, V, Peifer, M, Alexandrov, LB, Seidel, D, Leenders, F, Maas, L, Müller, C, Dahmen, I, Delhomme, TM, Ardin, M, Leblay, N, Byrnes, G, Sun, R, De Reynies, A, McLeer-Florin, A, Bosco, G, Malchers, F, Menon, R, Altmüller, J, Becker, C, Nürnberg, P, Achter, V, Lang, U, Schneider, PM, Bogus, M, Soloway, MG, Wilkerson, MD, Cun, Y, McKay, JD, Moro-Sibilot, D, Brambilla, CG, Lantuejoul, S, Lemaitre, N, Soltermann, A, Weder, W, Tischler, V, Brustugun, OT, Lund-Iversen, M, Helland, Å, Solberg, S, Ansén, S, Wright, G, Solomon, B, Roz, L, Pastorino, U, Petersen, I, Clement, JH, Sänger, J & Perner, S 2018, 'Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors' Nature communications, Jg. 9, Nr. 1, S. 1048. DOI: 10.1038/s41467-018-03099-x

Jappe, U, Minge, S, Kreft, B, Ludwig, A, Przybilla, B, Walker, A, Varga, R, Seidel, P, Biedermann, T, Anemüller, W, Kromminga, A, Ruëff, F, Merk, H, Wagner, N, Treudler, R, Worm, M, Waldmann, I, Saloga, J, Becker, WM, Goldmann, T, Platts-Mills, TA & Homann, A 2018, 'Meat allergy associated with α-Gal - Closing diagnostic gaps by anti-α-Gal IgE immune profiling' ALLERGY, Jg. 73, Nr. 1, S. 93-105. DOI: 10.1111/all.13238

Yamada, N, Martin, LB, Zechendorf, E, Purvis, GSD, Chiazza, F, Varrone, B, Collino, M, Shepherd, J, Heinbockel, L, Gutsmann, T, Correa Vargas, WA, Brandenburg, K, Marx, G, Schuerholz, T, Brohi, K & Thiemermann, C 2018, 'Novel Synthetic, Host-defense Peptide Protects Against Organ Injury/Dysfunction in a Rat Model of Severe Hemorrhagic Shock' American journal of surgical pathology, Jg. 268, Nr. 2, S. 348-356. DOI: 10.1097/SLA.0000000000002186

Chen, X, Bernemann, C, Tolkach, Y, Heller, M, Nientiedt, C, Falkenstein, M, Herpel, E, Jenzer, M, Grüllich, C, Jäger, D, Sültmann, H, Duensing, A, Perner, S, Cronauer, MV, Stephan, C, Debus, J, Schrader, AJ, Kristiansen, G, Hohenfellner, M & Duensing, S 2018, 'Overexpression of nuclear AR-V7 protein in primary prostate cancer is an independent negative prognostic marker in men with high-risk disease receiving adjuvant therapy' Urologic oncology, Jg. 36, Nr. 4, S. 161.e19-161.e30. DOI: 10.1016/j.urolonc.2017.11.001

Kuhlmann, N, Heinbockel, L, Correa, W, Gutsmann, T, Goldmann, T, Englisch, U & Brandenburg, K 2018, 'Peptide drug stability: The anti-inflammatory drugs Pep19-2.5 and Pep19-4LF in cream formulation' European journal of pharmaceutical sciences, Jg. 115, S. 240-247. DOI: 10.1016/j.ejps.2018.01.022

Heinemann, FG, Tolkach, Y, Deng, M, Schmidt, D, Perner, S, Kristiansen, G, Müller, SC & Ellinger, J 2018, 'Serum miR-122-5p and miR-206 expression: non-invasive prognostic biomarkers for renal cell carcinoma' Clinical epigenetics, Jg. 10, S. 11. DOI: 10.1186/s13148-018-0444-9

Vreka, M, Lilis, I, Papageorgopoulou, M, Giotopoulou, GA, Lianou, M, Giopanou, I, Kanellakis, NI, Spella, M, Agalioti, T, Armenis, V, Goldmann, T, Marwitz, S, Yull, FE, Blackwell, TS, Pasparakis, M, Marazioti, A & Stathopoulos, GT 2018, 'ΙκΒ kinase α is required for development and progression of KRAS-mutant lung adenocarcinoma' Cancer Research, Jg. 78, Nr. 11, S. 2939-2951. DOI: 10.1158/0008-5472.CAN-17-1944


2017

Schmitt, A, Knittel, G, Welcker, D, Yang, T-P, George, J, Nowak, M, Leeser, U, Buttner, R, Perner, S, Peifer, M & Reinhardt, HC 2017, 'ATM deficiency is associated with sensitivity to PARP1 and ATR inhibitors in lung adenocarcinoma' Cancer Research, Bd 77, Nr. 11, S. 3040-3056. DOI: 10.1158/0008-5472.CAN-16-3398

Marwitz, S & Goldmann, T 2017, 'Back into focus: tumour-associated macrophages and their role in immune checkpoint inhibition' Translational Cancer Research, Bd 6, Nr. supp6. DOI: 10.21037/tcr.2017.07.18

Schecher, S, Walter, B, Falkenstein, M, Macher-Goeppinger, S, Stenzel, P, Krümpelmann, K, Hadaschik, B, Perner, S, Kristiansen, G, Duensing, S, Roth, W & Tagscherer, KE 2017, 'Cyclin K dependent regulation of Aurora B affects apoptosis and proliferation by induction of mitotic catastrophe in prostate cancer' INTERNATIONAL JOURNAL OF CANCER , Bd 141, Nr. 8, S. 1643-1653. DOI: 10.1002/ijc.30864

Zhang, Y, Wang, X, Perner, S, Bánkfalvi, Á & Schlücker, S 2017, 'Effect of antigen retrieval methods on non-specific binding of anti-body-metal nanoparticle conjugates on FFPE tissue' ANALYTICAL CHEMISTRY . DOI: 10.1021/acs.analchem.7b03144

Watz, H, Uddin, M, Pedersen, F, Kirsten, A-M, Goldmann, T, Stellmacher, F, Groth, E, Larsson, B, Böttcher, G, Malmgren, A, Kraan, M & Rabe, KF 2017, 'Effects of the CXCR2 antagonist AZD5069 on lung neutrophil recruitment in asthma' PULMONARY PHARMACOLOGY & THERAPEUTICS , Bd 45, S. 121-123. DOI: 10.1016/j.pupt.2017.05.012

Deng, M, Brägelmann, J, Kryukov, I, Saraiva-Agostinho, N & Perner, S 2017, 'FirebrowseR: an R client to the Broad Institute's Firehose Pipeline' Database : the journal of biological databases and curation, Bd 2017, S. pii baw160. DOI: 10.1093/database/baw160

Ritter, M, Tamadaho, RS, Feid, J, Vogel, W, Wiszniewsky, K, Perner, S, Hoerauf, A & Layland, LE 2017, 'IL-4/5 signalling plays an important role during Litomosoides sigmodontis infection, influencing both immune system regulation and tissue pathology in the thoracic cavity' INTERNATIONAL JOURNAL FOR PARASITOLOGY, Bd 47, Nr. 14, S. 951-960. DOI: 10.1016/j.ijpara.2017.06.009

Laban, S, Giebel, G, Klümper, N, Schröck, A, Doescher, J, Spagnoli, G, Thierauf, J, Theodoraki, M-N, Remark, R, Gnjatic, S, Krupar, R, Sikora, AG, Litjens, G, Grabe, N, Kristiansen, G, Bootz, F, Schuler, PJ, Brunner, C, Brägelmann, J, Hoffmann, TK & Perner, S 2017, 'MAGE expression in head and neck squamous cell carcinoma primary tumors, lymph node metastases and respective recurrencesimplications for immunotherapy' Oncotarget, Bd 8, Nr. 9, S. 14719-14735. DOI: 10.18632/oncotarget.14830

Offermann, A, Vlasic, I, Vogel, W, Ruiz, C, Zellweger, T, Rentsch, CA, Hagedorn, S, Behrends, J, Nowak, M, Merseburger, A, Bubendorf, L, Kirfel, J, Duensing, S, Shaikhibrahim, Z & Perner, S 2017, 'MED15 overexpression in prostate cancer arises during androgen deprivation therapy via PI3K/mTOR signaling' Oncotarget, Bd 8, Nr. 5, S. 7964-7976. DOI: 10.18632/oncotarget.13860

Klümper, N, Syring, I, Vogel, W, Schmidt, D, Müller, SC, Ellinger, J, Shaikhibrahim, Z, Brägelmann, J & Perner, S 2017, 'Mediator Complex Subunit MED1 Protein Expression Is Decreased during Bladder Cancer Progression' Frontiers in Medicine, Bd 4, Nr. 30. DOI: 10.3389/fmed.2017.00030

Kaufhold, I, Osbahr, S, Shima, K, Marwitz, S, Rohmann, K, Drömann, D, Goldmann, T, Dalhoff, K & Rupp, J 2017, 'Nontypeable Haemophilus influenzae (NTHi) directly interfere with the regulation of E-cadherin in lung epithelial cells' MICROBES AND INFECTION , Bd 19, Nr. 11, S. 560-566. DOI: 10.1016/j.micinf.2017.07.002

Brägelmann, J, Klümper, N, Offermann, A, von Mässenhausen, A, Böhm, D, Deng, M, Queisser, A, Sanders, C, Syring, I, Merseburger, AS, Vogel, W, Sievers, E, Vlasic, I, Carlsson, J, Andrén, O, Brossart, P, Duensing, S, Svensson, MA, Shaikhibrahim, Z, Kirfel, J & Perner, S 2017, 'Pan-cancer analysis of the Mediator complex transcriptome identifies CDK19 and CDK8 as therapeutic targets in advanced prostate cancer' CLINICAL CANCER RESEARCH , Bd 23, Nr. 7, S. 1829-1840. DOI: 10.1158/1078-0432.CCR-16-0094

Wang, H, Schaefer, T, Konantz, M, Braun, M, Varga, Z, Paczulla, AM, Reich, S, Jacob, F, Perner, S, Moch, H, Fehm, T, Kanz, L, Schulze-Osthoff, K & Lengerke, C 2017, 'Prominent oncogenic roles of EVI1 in breast carcinoma' Cancer Research, Bd 77, Nr. 8, S. 2148-2160. DOI: 10.1158/0008-5472.CAN-16-0593

von Klot, CA, Kuczyk, MA, Boeker, A, Reuter, C, Imkamp, F, Herrmann, TRW, Tezval, H, Kramer, MW, Perner, S & Merseburger, AS 2017, 'Role of free testosterone levels in patients with metastatic castration-resistant prostate cancer receiving second-line therapy' Oncology Letters, Bd 13, Nr. 1, S. 22-28. DOI: 10.3892/ol.2016.5392

Lautenschläger, I, Wong, YL, Sarau, J, Goldmann, T, Zitta, K, Albrecht, M, Frerichs, I, Weiler, N & Uhlig, S 2017, 'Signalling mechanisms in PAF-induced intestinal failure' Scientific Reports, Bd 7, Nr. 1, S. 13382. DOI: 10.1038/s41598-017-13850-x

Pfalzgraff, A, Heinbockel, L, Su, Q, Brandenburg, K & Weindl, G 2017, 'Synthetic anti-endotoxin peptides inhibit cytoplasmic LPS-mediated responses' BIOCHEMICAL PHARMACOLOGY , Bd 140, S. 64-72. DOI: 10.1016/j.bcp.2017.05.015

Müller, T, Fay, S, Vieira, RP, Karmouty-Quintana, H, Cicko, S, Ayata, K, Zissel, G, Goldmann, T, Lungarella, G, Ferrari, D, Di Virgilio, F, Robaye, B, Boeynaems, J-M, Blackburn, MR & Idzko, M 2017, 'The purinergic receptor subtype P2Y2 mediates chemotaxis of neutrophils and fibroblasts in fibrotic lung disease' Oncotarget, Bd 8, Nr. 22, S. 35962-35972. DOI: 10.18632/oncotarget.16414