Priority Research Area Chronic Lung Diseases
Pulmonary Immune Diseases
Mission Projects Funding Techniques Publications Staff
Our mission is the investigation of autoimmune mechanisms as pathogenic principles in chronic lung diseases.
According to the central hypothesis of our group, functional autoantibodies against specific GPCRs are involved in the pathogenesis of systemic autoimmune diseases as well as asthma and COPD. We investigate Systemic Sclerosis (SSc), an autoimmune disease which is characterized by severe complications in the lung like pulmonary hypertension, lung fibrosis, and lung inflammation as a model disorder. As a Liaison Group with the Department of Rheumatology at the University of Lübeck we are committed to the close translational interchange between basic research and clinical application.