Priority Research Area Infections
Molecular and Experimental Mycobacteriology
Mission
Projects
Funding
Techniques
Publications
Staff
Publications
2021
ECDC molecular surveillance project participants, Tagliani, E, Anthony, R, Kohl, TA, de Neeling, A, Nikolayevskyy, V, Ködmön, C, Maurer, FP, Niemann, S, van Soolingen, D, van der Werf, MJ & Cirillo, DM 2021, 'Use of a Whole Genome Sequencing-based approach for Mycobacterium tuberculosis surveillance in Europe in 2017-2019: an ECDC pilot study', The European respiratory journal, Jg. 57, Nr. 1. https://doi.org/10.1183/13993003.02272-2020
2020
Alio, I, Gudzuhn, M, Pérez García, P, Danso, D, Schoelmerich, M, Mamat, U, Schaible, UE, Steinmann, J, Yero, D, Gibert, I, Kohl, TA, Niemann, S, Gröschel, MI, Haerdter, J, Hackl, T, Vollstedt, C, Bömeke, M, Egelkamp, R, Daniel, R, Poehlein, A & Streit, WR 2020, 'Phenotypic and Transcriptomic Analyses of Seven Clinical Stenotrophomonas maltophilia Isolates Identify a Small Set of Shared and Commonly Regulated Genes Involved in the Biofilm Lifestyle', APPLIED AND ENVIRONMENTAL MICROBIOLOGY , Jg. 86, Nr. 24. https://doi.org/10.1128/AEM.02038-20
Andres, S, Merker, M, Heyckendorf, J, Kalsdorf, B, Rumetshofer, R, Indra, A, Hofmann-Thiel, S, Hoffmann, H, Lange, C, Niemann, S & Maurer, FP 2020, 'Bedaquiline-resistant Tuberculosis:Dark Clouds on the Horizon', American journal of respiratory and critical care medicine, Jg. 201, Nr. 12, S. 1564-1568. https://doi.org/10.1164/rccm.201909-1819LE
Battaglia, S, Spitaleri, A, Cabibbe, AM, Meehan, CJ, Utpatel, C, Ismail, N, Tahseen, S, Skrahina, A, Alikhanova, N, Mostofa Kamal, SM, Barbova, A, Niemann, S, Groenheit, R, Dean, AS, Zignol, M, Rigouts, L & Cirillo, DM 2020, 'Characterization of genomic variants associated with resistance to bedaquiline and delamanid in naïve Mycobacterium tuberculosis clinical strains', JOURNAL OF CLINICAL MICROBIOLOGY. https://doi.org/10.1128/JCM.01304-20
Beckert, P, Sanchez-Padilla, E, Merker, M, Dreyer, V, Kohl, TA, Utpatel, C, Köser, CU, Barilar, I, Ismail, N, Omar, SV, Klopper, M, Warren, RM, Hoffmann, H, Maphalala, G, Ardizzoni, E, de Jong, BC, Kerschberger, B, Schramm, B, Andres, S, Kranzer, K, Maurer, FP, Bonnet, M & Niemann, S 2020, 'MDR M. tuberculosis outbreak clone in Eswatini missed by Xpert has elevated bedaquiline resistance dated to the pre-treatment era', Genome medicine, Jg. 12, Nr. 1, S. 104. https://doi.org/10.1186/s13073-020-00793-8
Conceição, MLD, Conceição, EC, Furlaneto, IP, Silva, SPD, Guimarães, AEDS, Gomes, P, Boschiroli, ML, Michelet, L, Kohl, TA, Kranzer, K, Francez, LDC, Lima, LNGC, Portugal, I, Perdigão, J & Lima, KVB 2020, 'Phylogenomic Perspective on a Unique Mycobacterium bovis Clade Dominating Bovine Tuberculosis Infections among Cattle and Buffalos in Northern Brazil', Scientific Reports, Jg. 10, Nr. 1, S. 1747. https://doi.org/10.1038/s41598-020-58398-5
CRyPTIC Consortium & Niemann, S 2020, 'GenomegaMap: Within-Species Genome-Wide dN/dS Estimation from over 10,000 Genomes', Molecular biology and evolution, Jg. 37, Nr. 8, S. 2450-2460. https://doi.org/10.1093/molbev/msaa069
Dreyer, V, Utpatel, C, Kohl, TA, Barilar, I, Gröschel, MI, Feuerriegel, S & Niemann, S 2020, 'Detection of low-frequency resistance-mediating SNPs in next-generation sequencing data of Mycobacterium tuberculosis complex strains with binoSNP', Scientific Reports, Jg. 10, Nr. 1, S. 7874. https://doi.org/10.1038/s41598-020-64708-8
ECDC molecular surveillance project participants, Tagliani, E, Anthony, R, Kohl, TA, de Neeling, A, Nikolayevskyy, V, Ködmön, C, Maurer, FP, Niemann, S, van Soolingen, D, van der Werf, MJ & Cirillo, DM 2020, 'Use of a Whole Genome Sequencing-based approach for Mycobacterium tuberculosis surveillance in Europe in 2017-2019: an ECDC pilot study', The European respiratory journal. https://doi.org/10.1183/13993003.02272-2020
Ezewudo, M, Borens, A, Chiner-Oms, Á, Miotto, P, Chindelevitch, L, Starks, AM, Hanna, D, Liwski, R, Zignol, M, Gilpin, C, Niemann, S, Kohl, TA, Warren, RM, Crook, D, Gagneux, S, Hoffner, S, Rodrigues, C, Comas, I, Engelthaler, DM, Alland, D, Rigouts, L, Lange, C, Dheda, K, Hasan, R, McNerney, R, Cirillo, DM, Schito, M, Rodwell, TC & Posey, J 2020, 'Author Correction: Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase', Scientific Reports, Jg. 10, Nr. 1, S. 3531. https://doi.org/10.1038/s41598-020-58955-y
Feuerriegel, S, Kohl, TA, Utpatel, C, Andres, S, Maurer, FP, Heyckendorf, J, Jouet, A, Badalato, N, Foray, L, Kamara, RF, Conteh, OS, Supply, P & Niemann, S 2020, 'Rapid genomic first- and second-line drug resistance prediction from clinical Mycobacterium tuberculosis specimens using Deeplex®-MycTB', The European respiratory journal. https://doi.org/10.1183/13993003.01796-2020
Frentrup, M, Zhou, Z, Steglich, M, Meier-Kolthoff, JP, Göker, M, Riedel, T, Bunk, B, Spröer, C, Overmann, J, Blaschitz, M, Indra, A, von Müller, L, Kohl, TA, Niemann, S, Seyboldt, C, Klawonn, F, Kumar, N, Lawley, TD, García-Fernández, S, Cantón, R, Del Campo, R, Zimmermann, O, Groß, U, Achtman, M & Nübel, U 2020, 'A publicly accessible database for Clostridioides difficile genome sequences supports tracing of transmission chains and epidemics', Microbial genomics, Jg. 6, Nr. 8. https://doi.org/10.1099/mgen.0.000410
Godfroid, M, Dagan, T, Merker, M, Kohl, TA, Diel, R, Maurer, FP, Niemann, S & Kupczok, A 2020, 'Insertion and deletion evolution reflects antibiotics selection pressure in a Mycobacterium tuberculosis outbreak', PLOS PATHOGENS, Jg. 16, Nr. 9, S. e1008357. https://doi.org/10.1371/journal.ppat.1008357
Gröschel, MI, Meehan, CJ, Barilar, I, Diricks, M, Gonzaga, A, Steglich, M, Conchillo-Solé, O, Scherer, I-C, Mamat, U, Luz, CF, De Bruyne, K, Utpatel, C, Yero, D, Gibert, I, Daura, X, Kampmeier, S, Rahman, NA, Kresken, M, van der Werf, TS, Alio, I, Streit, WR, Zhou, K, Schwartz, T, Rossen, JWA, Farhat, MR, Schaible, UE, Nübel, U, Rupp, J, Steinmann, J, Niemann, S & Kohl, TA 2020, 'The phylogenetic landscape and nosocomial spread of the multidrug-resistant opportunist Stenotrophomonas maltophilia', Nature communications, Jg. 11, Nr. 1, S. 2044. https://doi.org/10.1038/s41467-020-15123-0
Hess, JF, Kohl, TA, Kotrová, M, Roensch, K, Paprotka, T, Mohr, V, Hutzenlaub, T, Brüggemann, M, Zengerle, R, Niemann, S & Paust, N 2020, 'Library preparation for next generation sequencing: A review of automation strategies', Biotechnology advances, Jg. 41, S. 107537. https://doi.org/10.1016/j.biotechadv.2020.107537
Homolka, S, Paulowski, L, Andres, S, Hillemann, D, Jou, R, Günther, G, Claassens, M, Kuhns, M, Niemann, S & Maurer, FP 2020, 'Two Pandemics, One Challenge-Leveraging Molecular Test Capacity of Tuberculosis Laboratories for Rapid COVID-19 Case-Finding', EMERGING INFECTIOUS DISEASES, Jg. 26, Nr. 11. https://doi.org/10.3201/eid2611.202602
Lange, C, Aarnoutse, R, Chesov, D, van Crevel, R, Gillespie, SH, Grobbel, H-P, Kalsdorf, B, Kontsevaya, I, van Laarhoven, A, Nishiguchi, T, Mandalakas, A, Merker, M, Niemann, S, Köhler, N, Heyckendorf, J, Reimann, M, Ruhwald, M, Sanchez-Carballo, P, Schwudke, D, Waldow, F & DiNardo, AR 2020, 'Perspective for Precision Medicine for Tuberculosis', FRONTIERS IN IMMUNOLOGY, Jg. 11, S. 566608. https://doi.org/10.3389/fimmu.2020.566608
Klopper, M, Heupink, TH, Hill-Cawthorne, G, Streicher, EM, Dippenaar, A, de Vos, M, Abdallah, AM, Limberis, J, Merker, M, Burns, S, Niemann, S, Dheda, K, Posey, J, Pain, A & Warren, RM 2020, 'A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic', BMC Medicine, Jg. 18, Nr. 1, S. 24. https://doi.org/10.1186/s12916-019-1487-2
Kohl, TA, Kranzer, K, Andres, S, Wirth, T, Niemann, S & Moser, I 2020, 'Population structure of Mycobacterium bovis in Germany: A long-term study using Whole Genome Sequencing combined with conventional molecular typing methods', JOURNAL OF CLINICAL MICROBIOLOGY. https://doi.org/10.1128/JCM.01573-20
M. chimaera ISCVID investigators 2020, 'International Society of Cardiovascular Infectious Diseases Guidelines for the Diagnosis, Treatment and Prevention of Disseminated Mycobacterium chimaera Infection Following Cardiac Surgery with Cardiopulmonary Bypass', Journal of hospital infection, Jg. 104, Nr. 2, S. 214-235. https://doi.org/10.1016/j.jhin.2019.10.009
Merker, M, Kohl, TA, Barilar, I, Andres, S, Fowler, PW, Chryssanthou, E, Ängeby, K, Jureen, P, Moradigaravand, D, Parkhill, J, Peacock, SJ, Schön, T, Maurer, FP, Walker, T, Köser, C & Niemann, S 2020, 'Phylogenetically informative mutations in genes implicated in antibiotic resistance in Mycobacterium tuberculosis complex', Genome medicine, Jg. 12, Nr. 1, S. 27. https://doi.org/10.1186/s13073-020-00726-5
Merker, M, Nikolaevskaya, E, Kohl, TA, Molina-Moya, B, Pavlovska, O, Brännberg, P, Dudnyk, A, Stokich, V, Barilar, I, Marynova, I, Filipova, T, Prat, C, Sjöstedt, A, Dominguez, J, Rzhepishevska, O & Niemann, S 2020, 'Multidrug- and Extensively Drug-Resistant Mycobacterium tuberculosis Beijing Clades, Ukraine, 2015', EMERGING INFECTIOUS DISEASES, Jg. 26, Nr. 3, S. 481-490. https://doi.org/10.3201/eid2603.190525
Merker, M, Tueffers, L, Vallier, M, Groth, EE, Sonnenkalb, L, Unterweger, D, Baines, JF, Niemann, S & Schulenburg, H 2020, 'Evolutionary Approaches to Combat Antibiotic Resistance:Opportunities and Challenges for Precision Medicine', FRONTIERS IN IMMUNOLOGY, Jg. 11, S. 1938. https://doi.org/10.3389/fimmu.2020.01938
Shuaib, YA, Khalil, EAG, Wieler, LH, Schaible, UE, Bakheit, MA, Mohamed-Noor, SE, Abdalla, MA, Kerubo, G, Andres, S, Hillemann, D, Richter, E, Kranzer, K, Niemann, S & Merker, M 2020, 'Mycobacterium tuberculosis Complex Lineage 3 as Causative Agent of Pulmonary Tuberculosis, Eastern Sudan1', EMERGING INFECTIOUS DISEASES, Jg. 26, Nr. 3, S. 427-436. https://doi.org/10.3201/eid2603.191145
Wetzstein, N, Kohl, TA, Andres, S, Schultze, TG, Geil, A, Kim, E, Biciusca, T, Hügel, C, Hogardt, M, Lehn, A, Vehreschild, MJGT, Wolf, T, Niemann, S, Maurer, FP & Wichelhaus, TA 2020, 'Comparative analysis of phenotypic and genotypic antibiotic susceptibility patterns in Mycobacterium avium complex', INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES , Jg. 93, S. 320-328. https://doi.org/10.1016/j.ijid.2020.02.059
Wetzstein, N, Kohl, TA, Schultze, TG, Andres, S, Bellinghausen, C, Hügel, C, Kempf, VAJ, Lehn, A, Hogardt, M, Serve, H, Vehreschild, MJGT, Wolf, T, Niemann, S, Maurer, FP & Wichelhaus, TA 2020, 'Antimicrobial susceptibility and phylogenetic relations in a German cohort infected with Mycobacterium abscessus', JOURNAL OF CLINICAL MICROBIOLOGY. https://doi.org/10.1128/JCM.01813-20
2019
Andres, S, Gröschel, MI, Hillemann, D, Merker, M, Niemann, S & Kranzer, K 2019, 'A Diagnostic Algorithm To Investigate Pyrazinamide and Ethambutol Resistance in Rifampin-Resistant Mycobacterium tuberculosis Isolates in a Low-Incidence Setting', ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Jg. 63, Nr. 2. https://doi.org/10.1128/AAC.01798-18
Arandjelović, I, Merker, M, Richter, E, Kohl, TA, Savić, B, Soldatović, I, Wirth, T, Vuković, D & Niemann, S 2019, 'Longitudinal Outbreak of Multidrug-Resistant Tuberculosis in a Hospital Setting, Serbia', EMERGING INFECTIOUS DISEASES, Jg. 25, Nr. 3, S. 555-558. https://doi.org/10.3201/eid2503.181220
Borrell, S, Trauner, A, Brites, D, Rigouts, L, Loiseau, C, Coscolla, M, Niemann, S, De Jong, B, Yeboah-Manu, D, Kato-Maeda, M, Feldmann, J, Reinhard, M, Beisel, C & Gagneux, S 2019, 'Reference set of Mycobacterium tuberculosis clinical strains: A tool for research and product development', PLOS ONE, Jg. 14, Nr. 3, S. e0214088. https://doi.org/10.1371/journal.pone.0214088
Diel, R, Kohl, TA, Maurer, FP, Merker, M, Meywald Walter, K, Hannemann, J, Nienhaus, A, Supply, P & Niemann, S 2019, 'Accuracy of whole genome sequencing to determine recent tuberculosis transmission: an 11-year population-based study in Hamburg, Germany', The European respiratory journal, Jg. 54, Nr. 5. https://doi.org/10.1183/13993003.01154-2019
Engström, A, Antonenka, U, Kadyrov, A, Kalmambetova, G, Kranzer, K, Merker, M, Kabirov, O, Parpieva, N, Rajabov, A, Sahalchyk, E, Sayfudtinov, Z, Niemann, S & Hoffmann, H 2019, 'Population structure of drug-resistant Mycobacterium tuberculosis in Central Asia', BMC INFECTIOUS DISEASES , Jg. 19, Nr. 1, S. 908. https://doi.org/10.1186/s12879-019-4480-7
Ghodousi, A, Tagliani, E, Karunaratne, E, Niemann, S, Perera, J, Köser, CU & Cirillo, DM 2019, 'Isoniazid Resistance in Mycobacterium tuberculosis Is a Heterogeneous Phenotype Composed of Overlapping MIC Distributions with Different Underlying Resistance Mechanisms', ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Jg. 63, Nr. 7. https://doi.org/10.1128/AAC.00092-19
Havlicek, J, Dachsel, B, Slickers, P, Andres, S, Beckert, P, Feuerriegel, S, Niemann, S, Merker, M & Labugger, I 2019, 'Rapid microarray-based assay for detection of pyrazinamide resistant Mycobacterium tuberculosis', Diagnostic microbiology and infectious disease, Jg. 94, Nr. 2, S. 147-154. https://doi.org/10.1016/j.diagmicrobio.2018.12.011
Homolka, S, Zallet, J, Albert, H, Witt, A-K & Kranzer, K 2019, 'Introduction of quality management in a National Reference Laboratory in Germany', PLOS ONE, Jg. 14, Nr. 10, S. e0222925. https://doi.org/10.1371/journal.pone.0222925
Hunt, M, Bradley, P, Lapierre, SG, Heys, S, Thomsit, M, Hall, MB, Malone, KM, Wintringer, P, Walker, TM, Cirillo, DM, Comas, I, Farhat, MR, Fowler, P, Gardy, J, Ismail, N, Kohl, TA, Mathys, V, Merker, M, Niemann, S, Omar, SV, Sintchenko, V, Smith, G, van Soolingen, D, Supply, P, Tahseen, S, Wilcox, M, Arandjelovic, I, Peto, TEA, Crook, DW & Iqbal, Z 2019, 'Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe', Wellcome open research, Jg. 4, S. 191. https://doi.org/10.12688/wellcomeopenres.15603.1
Ismail, NA, Said, HM, Rodrigues, C, Omar, SV, Ajbani, K, Sukhadiad, N, Kohl, TA, Niemann, S, Kranzer, K, Diels, M, Rigouts, L, Rüsch-Gerdes, S & Siddiqi, S 2019, 'Multicentre study to establish interpretive criteria for clofazimine drug susceptibility testing', INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Jg. 23, Nr. 5, S. 594-599. https://doi.org/10.5588/ijtld.18.0417
Jajou, R, Kohl, TA, Walker, T, Norman, A, Cirillo, DM, Tagliani, E, Niemann, S, de Neeling, A, Lillebaek, T, Anthony, RM & van Soolingen, D 2019, 'Towards standardisation: comparison of five whole genome sequencing (WGS) analysis pipelines for detection of epidemiologically linked tuberculosis cases', Eurosurveillance, Jg. 24, Nr. 50. https://doi.org/10.2807/1560-7917.ES.2019.24.50.1900130
Lipworth, S, Jajou, R, de Neeling, A, Bradley, P, van der Hoek, W, Maphalala, G, Bonnet, M, Sanchez-Padilla, E, Diel, R, Niemann, S, Iqbal, Z, Smith, G, Peto, T, Crook, D, Walker, T & van Soolingen, D 2019, 'SNP-IT Tool for Identifying Subspecies and Associated Lineages of Mycobacterium tuberculosis Complex', EMERGING INFECTIOUS DISEASES, Jg. 25, Nr. 3, S. 482-488. https://doi.org/10.3201/eid2503.180894
Loiseau, C, Brites, D, Moser, I, Coll, F, Pourcel, C, Robbe-Austerman, S, Escuyer, V, Musser, KA, Peacock, SJ, Feuerriegel, S, Kohl, TA, Niemann, S, Gagneux, S & Köser, CU 2019, 'Revised Interpretation of the Hain Lifescience GenoType MTBC To Differentiate Mycobacterium canettii and Members of the Mycobacterium tuberculosis Complex.', ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Jg. 63, Nr. 6. https://doi.org/10.1128/AAC.00159-19
Meehan, CJ, Goig, GA, Kohl, TA, Verboven, L, Dippenaar, A, Ezewudo, M, Farhat, MR, Guthrie, JL, Laukens, K, Miotto, P, Ofori-Anyinam, B, Dreyer, V, Supply, P, Suresh, A, Utpatel, C, van Soolingen, D, Zhou, Y, Ashton, PM, Brites, D, Cabibbe, AM, de Jong, BC, de Vos, M, Menardo, F, Gagneux, S, Gao, Q, Heupink, TH, Liu, Q, Loiseau, C, Rigouts, L, Rodwell, TC, Tagliani, E, Walker, TM, Warren, RM, Zhao, Y, Zignol, M, Schito, M, Gardy, J, Cirillo, DM, Niemann, S, Comas, I & Van Rie, A 2019, 'Whole genome sequencing of Mycobacterium tuberculosis:current standards and open issues', Nature reviews. Microbiology, Jg. 17, Nr. 9, S. 533-545. https://doi.org/10.1038/s41579-019-0214-5
Nikolayevskyy, V, Niemann, S, Anthony, R, van Soolingen, D, Tagliani, E, Ködmön, C, van der Werf, MJ & Cirillo, DM 2019, 'Role and value of whole genome sequencing in studying tuberculosis transmission', CLINICAL MICROBIOLOGY AND INFECTION , Jg. 25, Nr. 11, S. 1377-1382. https://doi.org/10.1016/j.cmi.2019.03.022
Obeng-Nkrumah, N, Labi, A-K, Blankson, H, Awuah-Mensah, G, Oduro-Mensah, D, Anum, J, Teye, J, Kwashie, SD, Bako, E, Ayeh-Kumi, PF & Asmah, R 2019, 'Household cockroaches carry CTX-M-15-, OXA-48- and NDM-1-producing enterobacteria, and share beta-lactam resistance determinants with humans', BMC MICROBIOLOGY, Jg. 19, Nr. 1, 272. https://doi.org/10.1186/s12866-019-1629-x
Polsfuss, S, Hofmann-Thiel, S, Merker, M, Krieger, D, Niemann, S, Rüssmann, H, Schönfeld, N, Hoffmann, H & Kranzer, K 2019, 'Emergence of Low-level Delamanid and Bedaquiline Resistance During Extremely Drug-resistant Tuberculosis Treatment', CLINICAL INFECTIOUS DISEASES , Jg. 69, S. 1229-1231. https://doi.org/10.1093/cid/ciz074
Shitikov, E, Guliaev, A, Bespyatykh, J, Malakhova, M, Kolchenko, S, Smirnov, G, Merker, M, Niemann, S, Mokrousov, I, Ilina, E & Govorun, V 2019, 'The role of IS6110 in micro- and macroevolution of Mycobacterium tuberculosis lineage 2', Molecular phylogenetics and evolution, Jg. 139, S. 106559. https://doi.org/10.1016/j.ympev.2019.106559
Vaziri, F, Kohl, TA, Ghajavand, H, Kargarpour Kamakoli, M, Merker, M, Hadifar, S, Khanipour, S, Fateh, A, Masoumi, M, Siadat, SD & Niemann, S 2019, 'Genetic Diversity of Multi- and Extensively Drug-Resistant Mycobacterium tuberculosis Isolates in the Capital of Iran, Revealed by Whole-Genome Sequencing', JOURNAL OF CLINICAL MICROBIOLOGY, Jg. 57, Nr. 1, S. e01477-18. https://doi.org/10.1128/JCM.01477-18
Wood, HN, Venken, T, Willems, H, Jacobs, A, Reis, AJ, Almeida da Silva, PE, Homolka, S, Niemann, S, Rohde, KH & Hooyberghs, J 2019, 'Molecular drug susceptibility testing and strain typing of tuberculosis by DNA hybridization', PLOS ONE, Jg. 14, Nr. 2, S. e0212064. https://doi.org/10.1371/journal.pone.0212064
Lancet Respiratory Medicine drug-resistant tuberculosis Commission group, Niemann, S & Lange, C 2019, 'The Lancet Respiratory Medicine Commission: 2019 update: epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant and incurable tuberculosis', Lancet Respiratory Medicine, Jg. 7, Nr. 9, S. 820-826. https://doi.org/10.1016/S2213-2600(19)30263-2
CRyPTIC Consortium, Niemann, S & Kohl, T 2019, 'DeepAMR for predicting co-occurrent resistance of Mycobacterium tuberculosis', BIOINFORMATICS , Jg. 35, Nr. 18, S. 3240-3249. https://doi.org/10.1093/bioinformatics/btz067
CRyPTIC Consortium, Niemann, S, Merker, M & Kohl, T 2019, 'Application of machine learning techniques to tuberculosis drug resistance analysis', BIOINFORMATICS , Jg. 35, Nr. 13, S. 2276-2282. https://doi.org/10.1093/bioinformatics/bty949
2018
Acosta, F, Pérez-Lago, L, Ruiz Serrano, MJ, Marín, M, Kohl, TA, Lozano, N, Niemann, S, Valerio, M, Olmedo, M, Pérez-Granda, MJ, Pérez Pérez, MR, Bouza, E, Muñoz, P & García de Viedma, D 2018, 'Fast update of undetected Mycobacterium chimaera infections to reveal unsuspected cases' The Journal of hospital infection, Jg. 100, Nr. 4, S. 451-455. https://doi.org/10.1016/j.jhin.2018.08.018
Al-Ghafli, H, Kohl, TA, Merker, M, Varghese, B, Halees, A, Niemann, S & Al-Hajoj, S 2018, 'Drug-resistance profiling and transmission dynamics of multidrug-resistant Mycobacterium tuberculosis in Saudi Arabia revealed by whole genome sequencing' Infection and drug resistance, Jg. 11, S. 2219-2229. https://doi.org/10.2147/IDR.S181124
Andres, S, Gröschel, MI, Hillemann, D, Merker, M, Niemann, S & Kranzer, K 2018, 'A diagnostic algorithm to investigate pyrazinamide and ethambutol resistance in rifampicin resistant Mycobacterium tuberculosis isolates in a low incidence setting' ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. https://doi.org/10.1128/AAC.01798-18
Cabibbe, AM, Walker, TM, Niemann, S & Cirillo, DM 2018, 'Whole Genome Sequencing of Mycobacterium tuberculosis' The European respiratory journal, Jg. 52, Nr. 5, S. 1801163. https://doi.org/10.1183/13993003.01163-2018
Caño-Muñiz, S, Anthony, R, Niemann, S & Alffenaar, J-WC 2018, 'New Approaches and Therapeutic Options for Mycobacterium tuberculosis in a Dormant State' Clinical microbiology reviews, Jg. 31, Nr. 1. https://doi.org/10.1128/CMR.00060-17
CRyPTIC Consortium and the 100,000 Genomes Project 2018, 'Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing' New England Journal of Medicine, Jg. 379, Nr. 15, S. 1403-1415. https://doi.org/10.1056/NEJMoa1800474
CRyPTIC Consortiumfor the CRyPTIC Consortiumfor the CRyPTIC Consortium & Niemann, S 2018, 'Validating a 14-Drug Microtiter Plate Containing Bedaquiline and Delamanid for Large-Scale Research Susceptibility Testing of Mycobacterium tuberculosis' ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Jg. 62, Nr. 9. https://doi.org/10.1128/AAC.00344-18
EUSeqMyTB Consortium & Niemann, S 2018, 'EUSeqMyTB to set standards and build capacity for whole genome sequencing for tuberculosis in the EU' Lancet Infectious Diseases, Jg. 18, Nr. 4, S. 377. https://doi.org/10.1016/S1473-3099(18)30132-4
Global Tuberculosis Network (GTN) & Niemann, S 2018, 'Evolution of programmatic definitions used in tuberculosis prevention and care' CLINICAL INFECTIOUS DISEASES . https://doi.org/10.1093/cid/ciy990
Gröschel, MI, Walker, TM, van der Werf, TS, Lange, C, Niemann, S & Merker, M 2018, 'Pathogen-based precision medicine for drug-resistant tuberculosis' PLOS PATHOGENS, Jg. 14, Nr. 10, S. e1007297. https://doi.org/10.1371/journal.ppat.1007297
Havlicek, J, Dachsel, B, Slickers, P, Andres, S, Beckert, P, Feuerriegel, S, Niemann, S, Merker, M & Labugger, I 2018, 'Rapid Microarray-Based Detection of Rifampin, Isoniazid, and Fluoroquinolone Resistance in Mycobacterium tuberculosis by Use of a Single Cartridge' JOURNAL OF CLINICAL MICROBIOLOGY, Jg. 56, Nr. 2. https://doi.org/10.1128/JCM.01249-17
Heyckendorf, J, Andres, S, Köser, CU, Olaru, ID, Schön, T, Sturegård, E, Beckert, P, Schleusener, V, Kohl, TA, Hillemann, D, Moradigaravand, D, Parkhill, J, Peacock, SJ, Niemann, S, Lange, C & Merker, M 2018, 'What is resistance? Impact of phenotypic versus molecular drug resistance testing on multi- and extensively drug-resistant tuberculosis therapy: Impact of Phenotypic versus Molecular Drug Resistance Testing on Therapy for Multi- and Extensively Drug-Resistant Tuberculosis' ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Jg. 62, Nr. 2, S. e01550-17. https://doi.org/10.1128/AAC.01550-17
Kohl, TA, Harmsen, D, Rothgänger, J, Walker, T, Diel, R & Niemann, S 2018, 'Harmonized Genome Wide Typing of Tubercle Bacilli Using a Web-Based Gene-By-Gene Nomenclature System' EBioMedicine, Jg. 34, S. 131-138. https://doi.org/10.1016/j.ebiom.2018.07.030
Kohl, TA, Utpatel, C, Niemann, S & Moser, I 2018, 'Mycobacterium bovis Persistence in Two Different Captive Wild Animal Populations in Germany: a Longitudinal Molecular Epidemiological Study Revealing Pathogen Transmission by Whole-Genome Sequencing' JOURNAL OF CLINICAL MICROBIOLOGY, Jg. 56, Nr. 9. https://doi.org/10.1128/JCM.00302-18
Kohl, TA, Utpatel, C, Schleusener, V, De Filippo, MR, Beckert, P, Cirillo, DM & Niemann, S 2018, 'MTBseq: a comprehensive pipeline for whole genome sequence analysis of Mycobacterium tuberculosis complex isolates' PeerJ, Jg. 6, S. e5895. https://doi.org/10.7717/peerj.5895
Köser, CU, Heyckendorf, J, Andres, S, Olaru, ID, Schön, T, Sturegård, E, Beckert, P, Schleusener, V, Kohl, TA, Hillemann, D, Moradigaravand, D, Parkhill, J, Peacock, SJ, Niemann, S, Lange, C & Merker, M 2018, 'Reply to Dookie et al., "Whole-Genome Sequencing To Guide the Selection of Treatment for Drug-Resistant Tuberculosis"' ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Jg. 62, Nr. 8. https://doi.org/10.1128/AAC.00616-18
Lange, C, Alghamdi, WA, Al-Shaer, MH, Brighenti, S, Diacon, AH, DiNardo, AR, Grobbel, HP, Gröschel, MI, von Groote-Bidlingmaier, F, Hauptmann, M, Heyckendorf, J, Köhler, N, Kohl, TA, Merker, M, Niemann, S, Peloquin, CA, Reimann, M, Schaible, UE, Schaub, D, Schleusener, V, Thye, T & Schön, T 2018, 'Perspectives for personalized therapy for patients with multidrug-resistant tuberculosis' JOURNAL OF INTERNAL MEDICINE . https://doi.org/10.1111/joim.12780
Makhado, NA, Matabane, E, Faccin, M, Pinçon, C, Jouet, A, Boutachkourt, F, Goeminne, L, Gaudin, C, Maphalala, G, Beckert, P, Niemann, S, Delvenne, J-C, Delmée, M, Razwiedani, L, Nchabeleng, M, Supply, P, de Jong, BC & André, E 2018, 'Outbreak of multidrug-resistant tuberculosis in South Africa undetected by WHO-endorsed commercial tests: an observational study' Lancet Infectious Diseases, Jg. 18, Nr. 12, S. 1350-1359. https://doi.org/10.1016/S1473-3099(18)30496-1
Malm, S, Maaß, S, Schaible, UE, Ehlers, S & Niemann, S 2018, 'In vivo virulence of Mycobacterium tuberculosis depends on a single homologue of the LytR-CpsA-Psr proteins' Scientific Reports, Jg. 8, Nr. 1, S. 3936. https://doi.org/10.1038/s41598-018-22012-6
Meehan, CJ, Moris, P, Kohl, TA, Pečerska, J, Akter, S, Merker, M, Utpatel, C, Beckert, P, Gehre, F, Lempens, P, Stadler, T, Kaswa, MK, Kühnert, D, Niemann, S & de Jong, BC 2018, 'The relationship between transmission time and clustering methods in Mycobacterium tuberculosis epidemiology' EBioMedicine, Jg. 37, S. 410-416. https://doi.org/10.1016/j.ebiom.2018.10.013
Mekonnen, A, Merker, M, Collins, JM, Addise, D, Aseffa, A, Petros, B, Ameni, G & Niemann, S 2018, 'Molecular epidemiology and drug resistance patterns of Mycobacterium tuberculosis complex isolates from university students and the local community in Eastern Ethiopia' PLOS ONE, Jg. 13, Nr. 9, S. e0198054. https://doi.org/10.1371/journal.pone.0198054
Plate, A, Kohl, TA, Keller, PM, Majer, S, Fulchini, R, Strahm, C, Medugno, C, Rancic, Z, Husmann, L, Sax, H, Niemann, S & Hasse, B 2018, 'Aortic Endograft Infection with Mycobacterium chimaera and Granulicatella adiacens, Switzerland, 2014' EMERGING INFECTIOUS DISEASES, Jg. 24, Nr. 9, S. 1700-1704. https://doi.org/10.3201/eid2409.180247
Reiling, N, Homolka, S, Kohl, TA, Steinhäuser, C, Kolbe, K, Schütze, S & Brandenburg, J 2018, 'Shaping the niche in macrophages: Genetic diversity of the M. tuberculosis complex and its consequences for the infected host' INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, Jg. 308, Nr. 1, S. 118-128. https://doi.org/10.1016/j.ijmm.2017.09.009
Schleusener, V, Merker, M, Kohl, T & Niemann, S 2018, 'Tuberkulose: Neue Herausforderungen durch zunehmende Resistenzen' Der Pneumologe, Jg. 2018, Nr. 1, S. 35-41.
Shima, K, Wanker, M, Skilton, RJ, Cutcliffe, LT, Schnee, C, Kohl, TA, Niemann, S, Geijo, J, Klinger, M, Timms, P, Rattei, T, Sachse, K, Clarke, IN & Rupp, J 2018, 'The Genetic Transformation of Chlamydia pneumoniae' mSphere, Jg. 3, Nr. 5, e00412-18. https://doi.org/10.1128/mSphere.00412-18
Shuaib, YA, Khalil, EAG, Schaible, UE, Wieler, LH, Bakheit, MAM, Mohamed-Noor, SE, Abdalla, MA, Homolka, S, Andres, S, Hillemann, D, Lonnroth, K, Richter, E, Niemann, S & Kranzer, K 2018, 'Smear Microscopy for Diagnosis of Pulmonary Tuberculosis in Eastern Sudan' Tuberculosis research and treatment, Jg. 2018, S. 8038137. https://doi.org/10.1155/2018/8038137
Steinmann, J, Mamat, U, Abda, EM, Kirchhoff, L, Streit, WR, Schaible, UE, Niemann, S & Kohl, TA 2018, 'Analysis of Phylogenetic Variation of Reveals Human-Specific Branches' Frontiers in Microbiology, Jg. 9, S. 806. https://doi.org/10.3389/fmicb.2018.00806
Tortoli, E, Kohl, TA, Brown-Elliott, BA, Trovato, A, Cardoso-Leão, S, Garcia, MJ, Vasireddy, S, Turenne, CY, Griffith, DE, Philley, JV, Niemann, S, Wallace, RJ & Cirillo, DM 2018, 'Mycobacterium abscessus, a taxonomic puzzle' INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, Jg. 68, Nr. 1, S. 467-469. https://doi.org/10.1099/ijsem.0.002457
Vaziri, F, Kohl, TA, Ghajavand, H, Kargarpour Kamakoli, M, Merker, M, Hadifar, S, Khanipour, S, Fateh, A, Masoumi, M, Siadat, SD & Niemann, S 2018, 'The genetic diversity of multi and extensively drug resistant Mycobacterium tuberculosis in the capital of Iran revealed by whole genome sequencing' JOURNAL OF CLINICAL MICROBIOLOGY. https://doi.org/10.1128/JCM.01477-18
Walker, TM, Merker, M, Knoblauch, AM, Helbling, P, Schoch, OD, van der Werf, MJ, Kranzer, K, Fiebig, L, Kröger, S, Haas, W, Hoffmann, H, Indra, A, Egli, A, Cirillo, DM, Robert, J, Rogers, TR, Groenheit, R, Mengshoel, AT, Mathys, V, Haanperä, M, Soolingen, DV, Niemann, S, Böttger, EC, Keller, PM, MDR-TB Cluster Consortium & Lange, C 2018, 'A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study' Lancet Infectious Diseases, Jg. 18, Nr. 4, S. 431-440. https://doi.org/10.1016/S1473-3099(18)30004-5
Zignol, M, Cabibbe, AM, Dean, AS, Glaziou, P, Alikhanova, N, Ama, C, Andres, S, Barbova, A, Borbe-Reyes, A, Chin, DP, Cirillo, DM, Colvin, C, Dadu, A, Dreyer, A, Driesen, M, Gilpin, C, Hasan, R, Hasan, Z, Hoffner, S, Hussain, A, Ismail, N, Kamal, SMM, Khanzada, FM, Kimerling, M, Kohl, TA, Mansjö, M, Miotto, P, Mukadi, YD, Mvusi, L, Niemann, S, Omar, SV, Rigouts, L, Schito, M, Sela, I, Seyfaddinova, M, Skenders, G, Skrahina, A, Tahseen, S, Wells, WA, Zhurilo, A, Weyer, K, Floyd, K & Raviglione, MC 2018, 'Genetic sequencing for surveillance of drug resistance in tuberculosis in highly endemic countries: a multi-country population-based surveillance study' Lancet Infectious Diseases, Jg. 18, Nr. 6, S. 675-683. https://doi.org/10.1016/S1473-3099(18)30073-2
2017
Marais, BJ, Walker, TM, Cirillo, DM, Raviglione, M, Abubakar, I, van der Werf, MJ, Boehme, C, Niemann, S, Castro, KG, Zumla, A, Sintchenko, V & Crook, DW 2017, 'Aiming for zero tuberculosis transmission in low-burden countries' Lancet Respiratory Medicine, Bd 5, Nr. 11, S. 846-848. DOI: 10.1016/S2213-2600(17)30382-X
Fiebig, L, Kohl, TA, Popovici, O, Mühlenfeld, M, Indra, A, Homorodean, D, Chiotan, D, Richter, E, Rüsch-Gerdes, S, Schmidgruber, B, Beckert, P, Hauer, B, Niemann, S, Allerberger, F & Haas, W 2017, 'A joint cross-border investigation of a cluster of multidrug-resistant tuberculosis in Austria, Romania and Germany in 2014 using classic, genotyping and whole genome sequencing methods: lessons learned' Euro Surveillance, Bd 22, Nr. 2. DOI: 10.2807/1560-7917.ES.2017.22.2.30439
Havlicek, J, Rivera-Milla, E, Slickers, P, Andres, S, Feuerriegel, S, Niemann, S, Merker, M & Labugger, I 2017, 'An application of competitive reporter monitored amplification (CMA) for rapid detection of single nucleotide polymorphisms (SNPs)' PLOS ONE, Bd 12, Nr. 8, S. e0183561. DOI: 10.1371/journal.pone.0183561
Miotto, P, Tessema, B, Tagliani, E, Chindelevitch, L, Starks, AM, Emerson, C, Hanna, D, Kim, PS, Liwski, R, Zignol, M, Gilpin, C, Niemann, S, Denkinger, CM, Fleming, J, Warren, RM, Crook, D, Posey, J, Gagneux, S, Hoffner, S, Rodrigues, C, Comas, I, Engelthaler, DM, Murray, M, Alland, D, Rigouts, L, Lange, C, Dheda, K, Hasan, R, Ranganathan, UDK, McNerney, R, Ezewudo, M, Cirillo, DM, Schito, M, Köser, CU & Rodwell, TC 2017, 'A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis' The European respiratory journal, Bd 50, Nr. 6. DOI: 10.1183/13993003.01354-2017
Kolbe, K, Möckl, L, Sohst, V, Brandenburg, J, Engel, R, Malm, S, Bräuchle, C, Holst, O, Lindhorst, TK & Reiling, N 2017, 'Azido pentoses: A New Tool to Efficiently Label Mycobacterium tuberculosis Clinical Isolates' Chembiochem : a European journal of chemical biology, Bd 18, Nr. 13, S. 1172-1176. DOI: 10.1002/cbic.201600706
Andre, E, Goeminne, L, Cabibbe, A, Beckert, P, Kabamba Mukadi, B, Mathys, V, Gagneux, S, Niemann, S, Van Ingen, J & Cambau, E 2017, 'Consensus numbering system for the rifampicin resistance-associated rpoB gene mutations in pathogenic mycobacteria' CLINICAL MICROBIOLOGY AND INFECTION , Bd 23, Nr. 3, S. 167-172. DOI: 10.1016/j.cmi.2016.09.006
Labugger, I, Heyckendorf, J, Dees, S, Häussinger, E, Herzmann, C, Kohl, TA, Richter, E, Rivera-Milla, E & Lange, C 2017, 'Detection of transrenal DNA for the diagnosis of pulmonary tuberculosis and treatment monitoring' INFECTION, Bd 45, Nr. 3, S. 269-276. DOI: 10.1007/s15010-016-0955-2
Bjorn-Mortensen, K, Lillebaek, T, Koch, A, Soborg, B, Ladefoged, K, Sørensen, HCF, Kohl, TA, Niemann, S & Andersen, AB 2017, 'Extent of transmission captured by contact tracing in a tuberculosis high endemic setting' The European respiratory journal, Bd 49, Nr. 3. DOI: 10.1183/13993003.01851-2016
van Ingen, J, Kohl, TA, Kranzer, K, Hasse, B, Keller, PM, Katarzyna Szafrańska, A, Hillemann, D, Chand, M, Schreiber, PW, Sommerstein, R, Berger, C, Genoni, M, Rüegg, C, Troillet, N, Widmer, AF, Becker, SL, Herrmann, M, Eckmanns, T, Haller, S, Höller, C, Debast, SB, Wolfhagen, MJ, Hopman, J, Kluytmans, J, Langelaar, M, Notermans, DW, Ten Oever, J, van den Barselaar, P, Vonk, ABA, Vos, MC, Ahmed, N, Brown, T, Crook, DW, Lamagni, T, Phin, N, Smith, EG, Zambon, M, Serr, A, Götting, T, Ebner, W, Thürmer, A, Utpatel, C, Spröer, C, Bunk, B, Nübel, U, Bloemberg, GV, Böttger, EC, Niemann, S, Wagner, D & Sax, H 2017, 'Global outbreak of severe Mycobacterium chimaera disease after cardiac surgery: a molecular epidemiological study' Lancet Infectious Diseases, Bd 17, Nr. 10, S. 1033-1041. DOI: 10.1016/S1473-3099(17)30324-9
Mellmann, A, Andersen, PS, Bletz, S, Friedrich, AW, Kohl, TA, Lilje, B, Niemann, S, Prior, K, Rossen, JW & Harmsen, D 2017, 'High Interlaboratory Reproducibility and Accuracy of Next-Generation-Sequencing-Based Bacterial Genotyping in a Ring Trial' JOURNAL OF CLINICAL MICROBIOLOGY, Bd 55, Nr. 3, S. 908-913. DOI: 10.1128/JCM.02242-16
Bengtson, HN, Homolka, S, Niemann, S, Reis, AJ, da Silva, PE, Gerasimova, YV, Kolpashchikov, DM & Rohde, KH 2017, 'Multiplex detection of extensively drug resistant tuberculosis using binary deoxyribozyme sensors' Biosensors & Bioelectronics, Bd 94, S. 176-183. DOI: 10.1016/j.bios.2017.02.051
Tortoli, E, Kohl, TA, Trovato, A, Baldan, R, Campana, S, Cariani, L, Colombo, C, Costa, D, Cristadoro, S, Di Serio, MC, Manca, A, Pizzamiglio, G, Rancoita, PMV, Rossolini, GM, Taccetti, G, Teri, A, Niemann, S & Cirillo, DM 2017, 'Mycobacterium abscessus in patients with cystic fibrosis: low impact of inter-human transmission in Italy' The European respiratory journal, Bd 50, Nr. 1. DOI: 10.1183/13993003.02525-2016
Birmes, FS, Wolf, T, Kohl, TA, Rüger, K, Bange, F-C, Kalinowski, J & Fetzner, S 2017, 'Mycobacterium abscessus subsp. abscessus Is Capable of Degrading Pseudomonas aeruginosa Quinolone Signals' Frontiers in Microbiology, Bd 8, S. 339. DOI: 10.3389/fmicb.2017.00339
Schleusener, V, Köser, CU, Beckert, P, Niemann, S & Feuerriegel, S 2017, 'Mycobacterium tuberculosis resistance prediction and lineage classification from genome sequencing: comparison of automated analysis tools' Scientific Reports, Bd 7, S. 46327. DOI: 10.1038/srep46327
Malm, S, Linguissi, LSG, Tekwu, EM, Vouvoungui, JC, Kohl, TA, Beckert, P, Sidibe, A, Rüsch-Gerdes, S, Madzou-Laboum, IK, Kwedi, S, Penlap Beng, V, Frank, M, Ntoumi, F & Niemann, S 2017, 'New Mycobacterium tuberculosis Complex Sublineage, Brazzaville, Congo' EMERGING INFECTIOUS DISEASES, Bd 23, Nr. 3, S. 423-429. DOI: 10.3201/eid2303.160679
André, E, Goeminne, L, Colmant, A, Beckert, P, Niemann, S & Delmee, M 2017, 'Novel rapid PCR for the detection of Ile491Phe rpoB mutation of Mycobacterium tuberculosis, a rifampicin-resistance-conferring mutation undetected by commercial assays' CLINICAL MICROBIOLOGY AND INFECTION , Bd 23, Nr. 4, S. 267.e5-267.e7. DOI: 10.1016/j.cmi.2016.12.009
Wagner, NM, Van Aken, C, Butschkau, A, Bierhansl, L, Kellner, P, Schleusener, V, Seggewiss, J, Vollmar, B, Nöldge-Schomburg, G & Roesner, JP 2017, 'Procalcitonin impairs endothelial cell function and viability' ANESTHESIA AND ANALGESIA , Bd 124, Nr. 3, S. 836-845.
Stöckel, S, Meisel, S, Lorenz, B, Kloß, S, Henk, S, Dees, S, Richter, E, Andres, S, Merker, M, Labugger, I, Rösch, P & Popp, J 2017, 'Raman spectroscopic identification of Mycobacterium tuberculosis' Journal of Biophotonics, Bd 10, Nr. 5, S. 727-734. DOI: 10.1002/jbio.201600174
Nakatani, Y, Opel-Reading, HK, Merker, M, Machado, D, Andres, S, Kumar, SS, Moradigaravand, D, Coll, F, Perdigão, J, Portugal, I, Schön, T, Nair, D, Devi, KRU, Kohl, TA, Beckert, P, Clark, TG, Maphalala, G, Khumalo, D, Diel, R, Klaos, K, Aung, HL, Cook, GM, Parkhill, J, Peacock, SJ, Swaminathan, S, Viveiros, M, Niemann, S, Krause, KL & Köser, CU 2017, 'Role of alanine racemase mutations in Mycobacterium tuberculosis D-cycloserine resistance' ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Bd 61, Nr. 12, e01575-14. DOI: 10.1128/AAC.01575-17
Ajileye, A, Alvarez, N, Merker, M, Walker, TM, Akter, S, Brown, K, Moradigaravand, D, Schön, T, Andres, S, Schleusener, V, Omar, SV, Coll, F, Huang, H, Diel, R, Ismail, NA, Parkhill, J, de Jong, BC, Peto, TEA, Crook, DW, Niemann, S, Robledo, J, Smith, EG, Peacock, SJ & Köser, CU 2017, 'Some Synonymous and Nonsynonymous gyrA Mutations in Mycobacterium tuberculosis Lead to Systematic False-Positive Fluoroquinolone Resistance Results with the Hain GenoType MTBDRsl Assays' ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Bd 61, Nr. 4, S. e02169-16. DOI: 10.1128/AAC.02169-16
Dheda, K, Gumbo, T, Maartens, G, Dooley, KE, McNerney, R, Murray, M, Furin, J, Nardell, EA, London, L, Lessem, E, Theron, G, van Helden, PD, Niemann, S, Merker, M, Dowdy, D, Van Rie, A, Siu, GKH, Pasipanodya, JG, Rodrigues, C, Clark, TG, Sirgel, FA, Esmail, A, Lin, H-H, Atre, SR, Schaaf, HS, Chang, K-C, Lange, C, Nahid, P, Udwadia, ZF, Horsburgh, CR, Churchyard, GJ, Menzies, D, Hesseling, AC, Nuermberger, E, McIlleron, H, Fennelly, KP, Goemaere, E, Jaramillo, E, Low, M, Jara, CM, Padayatchi, N & Warren, RM 2017, 'The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis' Lancet Respiratory Medicine. DOI: 10.1016/S2213-2600(17)30079-6
Merker, M, Kohl, TA, Niemann, S & Supply, P 2017, 'The Evolution of Strain Typing in the Mycobacterium tuberculosis Complex' Advances in Experimental Medicine and Biology , Bd 1019, S. 43-78. DOI: 10.1007/978-3-319-64371-7_3
Heyckendorf, J, Andres, S, Köser, CU, Olaru, ID, Schön, T, Sturegård, E, Beckert, P, Schleusener, V, Kohl, TA, Hillemann, D, Moradigaravand, D, Parkhill, J, Peacock, SJ, Niemann, S, Lange, C & Merker, M 2017, 'What is resistance?: Impact of phenotypic versus molecular drug resistance testing on multi- and extensively drug-resistant tuberculosis therapy' ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. DOI: 10.1128/AAC.01550-17
2016
Ali, S, Beckert, P, Haileamlak, A, Wieser, A, Pritsch, M, Heinrich, N, Löscher, T, Hoelscher, M, Niemann, S & Rachow, A 2016, 'Drug resistance and population structure of M.tuberculosis isolates from prisons and communities in Ethiopia' BMC INFECTIOUS DISEASES , Bd 16, Nr. 1, S. 687. DOI: 10.1186/s12879-016-2041-x
Niemann, S, Merker, M, Kohl, T & Supply, P 2016, 'Impact of Genetic Diversity on the Biology of Mycobacterium tuberculosis Complex Strains' Microbiology spectrum, Bd 4, Nr. 6. DOI: 10.1128/microbiolspec.TBTB2-0022-2016
Zignol, M, Dean, AS, Alikhanova, N, Andres, S, Cabibbe, AM, Cirillo, DM, Dadu, A, Dreyer, A, Driesen, M, Gilpin, C, Hasan, R, Hasan, Z, Hoffner, S, Husain, A, Hussain, A, Ismail, N, Kamal, M, Mansjö, M, Mvusi, L, Niemann, S, Omar, SV, Qadeer, E, Rigouts, L, Rüsch-Gerdes, S, Schito, M, Seyfaddinova, M, Skrahina, A, Tahseen, S, Wells, WA, Mukadi, YD, Kimerling, M, Floyd, K, Weyer, K & Raviglione, MC 2016, 'Population-based resistance of Mycobacterium tuberculosis isolates to pyrazinamide and fluoroquinolones results from a multicountry surveillance project' Lancet Infectious Diseases, Bd 16, Nr. 10, S. 1185-92. DOI: 10.1016/S1473-3099(16)30190-6
Varma-Basil, M, Narang, A, Chakravorty, S, Garima, K, Gupta, S, Kumar Sharma, N, Giri, A, Zozio, T, Couvin, D, Hanif, M, Bhatnagar, A, Menon, B, Niemann, S, Rastogi, N, Alland, D & Bose, M 2016, 'A snapshot of the predominant single nucleotide polymorphism cluster groups of Mycobacterium tuberculosis clinical isolates in Delhi, India' Tuberculosis, Bd 100, S. 72-81. DOI: 10.1016/j.tube.2016.07.007
Mühlig, A, Bocklitz, T, Labugger, I, Dees, S, Henk, S, Richter, E, Andres, S, Merker, M, Stöckel, S, Weber, K, Cialla-May, D & Popp, J 2016, 'LOC-SERS: A Promising Closed System for the Identification of Mycobacteria' ANALYTICAL CHEMISTRY , Bd 88, Nr. 16, S. 7998-8004. DOI: 10.1021/acs.analchem.6b01152
Tortoli, E, Kohl, TA, Brown-Elliott, BA, Trovato, A, Cardoso Leao, S, Garcia, MJ, Vasireddy, S, Turenne, CY, Griffith, DE, Philley, JV, Baldan, R, Campana, S, Cariani, L, Colombo, C, Taccetti, G, Teri, A, Niemann, S, Wallace, RJ & Cirillo, DM 2016, 'Emended description of Mycobacterium abscessus, Mycobacterium abscessus subs. abscessus, Mycobacterium abscessus subsp. bolletii and designation of Mycobacterium abscessus subsp. massiliense comb. nov' INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY. DOI: 10.1099/ijsem.0.001376
Schena, E, Nedialkova, L, Borroni, E, Battaglia, S, Cabibbe, AM, Niemann, S, Utpatel, C, Merker, M, Trovato, A, Hofmann-Thiel, S, Hoffmann, H & Cirillo, DM 2016, 'Delamanid susceptibility testing of Mycobacterium tuberculosis using the resazurin microtitre assay and the BACTEC™ MGIT™ 960 system' JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, Bd 71, Nr. 6, S. 1532-9. DOI: 10.1093/jac/dkw044
Nikolayevskyy, V, Kranzer, K, Niemann, S & Drobniewski, F 2016, 'Whole genome sequencing of Mycobacterium tuberculosis for detection of recent transmission and tracing outbreaks: A systematic review' Tuberculosis, Bd 98, S. 77-85. DOI: 10.1016/j.tube.2016.02.009
Kaufmann, E, Spohr, C, Battenfeld, S, De Paepe, D, Holzhauser, T, Balks, E, Homolka, S, Reiling, N, Gilleron, M & Bastian, M 2016, 'BCG Vaccination Induces Robust CD4+ T Cell Responses to Mycobacterium tuberculosis Complex-Specific Lipopeptides in Guinea Pigs' JOURNAL OF IMMUNOLOGY, Bd 196, Nr. 6, S. 2723-2732. DOI: 10.4049/jimmunol.1502307
Merker, M, Crudu, V, Noroc, E, Romancenco, E, Chesov, D, Günther, G, Niemann, S & Lange, C 2016, 'In reply: The impact of mixed infections on the interpretation of molecular epidemiology studies of tuberculosis' INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Bd 20, Nr. 3, S. 424. DOI: 10.5588/ijtld.15.1024-2
Hoffmann, H, Kohl, TA, Hofmann-Thiel, S, Merker, M, Beckert, P, Jaton, K, Nedialkova, L, Sahalchyk, E, Rothe, T, Keller, PM & Niemann, S 2016, 'Delamanid and Bedaquiline Resistance in Mycobacterium tuberculosis Ancestral Beijing Genotype Causing Extensively Drug-Resistant Tuberculosis in a Tibetan Refugee' American journal of respiratory and critical care medicine, Bd 193, Nr. 3, S. 337-340. DOI: 10.1164/rccm.201502-0372LE
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