Programmbereich Infektionen

2023

Butov, D, Feshchenko, Y, Chesov, D, Myasoedov, V, Kuzhko, M, Dudnyk, A, Reimann, M, Hryshchuk, L, Yareshko, A, Tkachenko, A, Tarleeva, Y, Konstantynovska, O, Butova, T & Lange, C 2023, 'National survey on the impact of the war in Ukraine on TB diagnostics and treatment services in 2022', INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Jg. 27, Nr. 1, S. 86-88. https://doi.org/10.5588/ijtld.22.0563

European Tuberculosis Network TBNET 2023, 'Availability and costs of medicines for the treatment of tuberculosis in Europe', CLINICAL MICROBIOLOGY AND INFECTION , Jg. 29, Nr. 1, S. 77-84. https://doi.org/10.1016/j.cmi.2022.07.026

Hamada, Y, Gupta, RK, Quartagno, M, Izzard, A, Acuna-Villaorduna, C, Altet, N, Diel, R, Dominguez, J, Floyd, S, Gupta, A, Huerga, H, Jones-López, EC, Kinikar, A, Lange, C, van Leth, F, Liu, Q, Lu, W, Lu, P, Rueda, IL, Martinez, L, Mbandi, SK, Muñoz, L, Padilla, ES, Paradkar, M, Scriba, T, Sester, M, Shanaube, K, Sharma, SK, Sloot, R, Sotgiu, G, Thiruvengadam, K, Vashishtha, R, Abubakar, I & Rangaka, MX 2023, 'Predictive performance of interferon-gamma release assays and the tuberculin skin test for incident tuberculosis: an individual participant data meta-analysis', EClinicalMedicine, Jg. 56, S. 101815. https://doi.org/10.1016/j.eclinm.2022.101815

Koehler, N, Andres, S, Merker, M, Dreyer, V, John, A, Kuhns, M, Krieger, D, Choong, E, Verougstraete, N, Zur Wiesch, PA, Wicha, SG, König, C, Kalsdorf, B, Sanchez Carballo, PM, Schaub, D, Werngren, J, Schön, T, Peloquin, CA, Schönfeld, N, Verstraete, AG, Decosterd, LA, Aarnoutse, R, Niemann, S, Maurer, FP & Lange, C 2023, 'Pretomanid-Resistant Tuberculosis', Journal of infection. https://doi.org/10.1016/j.jinf.2023.01.039

Maier, C, Chesov, D, Schaub, D, Kalsdorf, B, Andres, S, Friesen, I, Reimann, M & Lange, C 2023, 'Long-term treatment outcomes in patients with multidrug-resistant tuberculosis', CLINICAL MICROBIOLOGY AND INFECTION . https://doi.org/10.1016/j.cmi.2023.02.013

TBNET and RESIST-TB networks 2023, 'Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a 2023 TBnet/RESIST-TB consensus statement', Lancet Infectious Diseases, Jg. 23, Nr. 4, S. e122-e137. https://doi.org/10.1016/S1473-3099(22)00875-1

UNITE4TB Consortium 2023, 'Implementing molecular tuberculosis diagnostic methods in limited-resource and high-burden countries', Breathe, Jg. 18, Nr. 4, S. 220226. https://doi.org/10.1183/20734735.0226-2022

 

2022

 

Akkerman, OW, Duarte, R, Tiberi, S, Schaaf, HS, Lange, C, Alffenaar, JWC, Denholm, J, Carvalho, ACC, Bolhuis, MS, Borisov, S, Bruchfeld, J, Cabibbe, AM, Caminero, JA, Carvalho, I, Chakaya, J, Centis, R, Dalcomo, MP, D Ambrosio, L, Dedicoat, M, Dheda, K, Dooley, KE, Furin, J, García-García, J-M, van Hest, NAH, de Jong, BC, Kurhasani, X, Märtson, AG, Mpagama, S, Torrico, MM, Nunes, E, Ong, CWM, Palmero, DJ, Ruslami, R, Saktiawati, AMI, Semuto, C, Silva, DR, Singla, R, Solovic, I, Srivastava, S, de Steenwinkel, JEM, Story, A, Sturkenboom, MGG, Tadolini, M, Udwadia, ZF, Verhage, AR, Zellweger, JP & Migliori, GB 2022, 'Clinical standards for drug-susceptible pulmonary TB', INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Jg. 26, Nr. 7, S. 592-604. https://doi.org/10.5588/ijtld.22.0228

Brandenburg, J, Heyckendorf, J, Marwitz, F, Zehethofer, N, Linnemann, L, Gisch, N, Karaköse, H, Reimann, M, Kranzer, K, Kalsdorf, B, Sanchez-Carballo, P, Weinkauf, M, Scholz, V, Malm, S, Homolka, S, Gaede, KI, Herzmann, C, Schaible, UE, Hölscher, C, Reiling, N & Schwudke, D 2022, 'Tuberculostearic Acid-Containing Phosphatidylinositols as Markers of Bacterial Burden in Tuberculosis', ACS infectious diseases, Jg. 8, Nr. 7, S. 1303-1315. https://doi.org/10.1021/acsinfecdis.2c00075

Chesov, E, Chesov, D, Maurer, FP, Andres, S, Utpatel, C, Barilar, I, Donica, A, Reimann, M, Niemann, S, Lange, C, Crudu, V, Heyckendorf, J & Merker, M 2022, 'Emergence of bedaquiline resistance in a high tuberculosis burden country', The European respiratory journal, Jg. 59, Nr. 3, 2100621. https://doi.org/10.1183/13993003.00621-2021

COVICAT study group, Aachen Study (COVAS) 2022, 'Detailed stratified GWAS analysis for severe COVID-19 in four European populations',  HUMAN MOLECULAR GENETICS , Jg. 31, Nr. 23, S. 3945-3966. https://doi.org/10.1093/hmg/ddac158

Donald, P, Kaufmann, S, Thee, S, Mandalakas, AM & Lange, C 2022, 'Pathogenesis of tuberculosis: the 1930 Lübeck disaster revisited', European Respiratory Review, Jg. 31, Nr. 164, 220046. https://doi.org/10.1183/16000617.0046-2022

DZIF-TB cohort study group 2022, 'Gene expression signatures identify biologically and clinically distinct tuberculosis endotypes', The European respiratory journal, Jg. 60, Nr. 3. https://doi.org/10.1183/13993003.02263-2021

European Conference on Infections in Leukaemia group 2022, 'Mycobacterial infections in adults with haematological malignancies and haematopoietic stem cell transplants: guidelines from the 8th European Conference on Infections in Leukaemia', Lancet Infectious Diseases, Jg. 22, Nr. 12, S. e359-e369. https://doi.org/10.1016/S1473-3099(22)00227-4

expert panel group for management recommendations in non-tuberculous mycobacterial pulmonary diseases 2022, 'Consensus management recommendations for less common non-tuberculous mycobacterial pulmonary diseases', Lancet Infectious Diseases, Jg. 22, Nr. 7, S. e178-e190. https://doi.org/10.1016/S1473-3099(21)00586-7

Günther, G, Saathoff, E, Rachow, A, Ekandjo, H, Diergaardt, A, Marais, N, Lange, C & Nepolo, E 2022, 'Clinical Evaluation of a Line-Probe Assay for Tuberculosis Detection and Drug-Resistance Prediction in Namibia', Microbiology spectrum, Jg. 10, Nr. 3, S. e0025922. https://doi.org/10.1128/spectrum.00259-22

Gutowski, J-P, Sachsenweger, J, May, K, Lange, C & Heyckendorf, J 2022, 'Eine unerwartete Komplikation: Kontralateraler Spannungspneumothorax nach transbronchialer Zangenbiopsie', Pneumologie (Stuttgart, Germany), Jg. 76, Nr. 9, S. 622-625. https://doi.org/10.1055/a-1775-5693

Lange, C, Aaby, P, Behr, MA, Donald, PR, Kaufmann, SHE, Netea, MG & Mandalakas, AM 2022, '100 years of Mycobacterium bovis bacille Calmette-Guérin', Lancet Infectious Diseases, Jg. 22, Nr. 1, S. e2-e12. https://doi.org/10.1016/S1473-3099(21)00403-5

Lange, C, Kay, A & Mandalakas, AM 2022, 'The need for effective drugs for TB prevention: set your goals high, and don´t stop till you get there', INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Jg. 26, Nr. 2, S. 85-88. https://doi.org/10.5588/ijtld.21.0736

Martinez, L, Cords, O, Liu, Q, Acuna-Villaorduna, C, Bonnet, M, Fox, GJ, Carvalho, ACC, Chan, P-C, Croda, J, Hill, PC, Lopez-Varela, E, Donkor, S, Fielding, K, Graham, SM, Espinal, MA, Kampmann, B, Reingold, A, Huerga, H, Villalba, JA, Grandjean, L, Sotgiu, G, Egere, U, Singh, S, Zhu, L, Lienhardt, C, Denholm, JT, Seddon, JA, Whalen, CC, García-Basteiro, AL, Triasih, R, Chen, C, Singh, J, Huang, L-M, Sharma, S, Hannoun, D, Del Corral, H, Mandalakas, AM, Malone, LL, Ling, D-L, Kritski, A, Stein, CM, Vashishtha, R, Boulahbal, F, Fang, C-T, Boom, WH, Netto, EM, Lemos, AC, Hesseling, AC, Kay, A, Jones-López, EC, Horsburgh, CR, Lange, C & Andrews, JR 2022, 'Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course: a systematic review and individual participant data meta-analysis', The Lancet. Global health, Jg. 10, Nr. 9, S. e1307-e1316. https://doi.org/10.1016/S2214-109X(22)00283-2

Mercier, T, Desfontaine, V, Cruchon, S, Da Silva Pereira Clara, JA, Briki, M, Mazza-Stalder, J, Kajkus, A, Burger, R, Suttels, V, Buclin, T, Opota, O, Koehler, N, Sanchez Carballo, PM, Lange, C, André, P, Decosterd, LA & Choong, E 2022, 'A battery of tandem mass spectrometry assays with stable isotope-dilution for the quantification of 15 anti-tuberculosis drugs and two metabolites in patients with susceptible-, multidrug-resistant- and extensively drug-resistant tuberculosis',  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, Jg. 1211, S. 123456. https://doi.org/10.1016/j.jchromb.2022.123456

Rachow, A, Saathoff, E, Mindru, R, Popescu, O, Lugoji, D, Mahler, B, Merker, M, Niemann, S, Olaru, ID, Kastner, S, Hoelscher, M, Lange, C & Ibraim, E 2022, 'Diagnostic performance of the AID line probe assay in the detection of Mycobacterium tuberculosis and drug resistance in Romanian patients with presumed TB', PLOS ONE, Jg. 17, Nr. 8, S. e0271297. https://doi.org/10.1371/journal.pone.0271297

Schaberg, T, Brinkmann, F, Feiterna-Sperling, C, Geerdes-Fenge, H, Hartmann, P, Häcker, B, Hauer, B, Haas, W, Heyckendorf, J, Lange, C, Maurer, FP, Nienhaus, A, Otto-Knapp, R, Priwitzer, M, Richter, E, Salzer, HJF, Schoch, O, Schönfeld, N, Stahlmann, R & Bauer, T 2022, 'Tuberkulose im Erwachsenenalter', Pneumologie (Stuttgart, Germany), Jg. 76, Nr. 11, S. 727-819. https://doi.org/10.1055/a-1934-8303

Sibandze, DB, Kay, A, Dreyer, V, Sikhondze, W, Dlamini, Q, DiNardo, A, Mtetwa, G, Lukhele, B, Vambe, D, Lange, C, Glenn Dlamini, M, Ness, T, Mejia, R, Kalsdorf, B, Heyckendorf, J, Kuhns, M, Maurer, FP, Dlamini, S, Maphalala, G, Niemann, S & Mandalakas, A 2022, 'Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing', Genome medicine, Jg. 14, Nr. 1, S. 52. https://doi.org/10.1186/s13073-022-01054-6

Study Group on Mycobacteria of the European Society of Microbiology and Infectious Diseases (ESGMYC), European Society of Mycobacteriology (ESM), European Respiratory Society (ERS) and 2022, 'Rifapentine access in Europe: growing concerns over key tuberculosis treatment component', The European respiratory journal, Jg. 59, Nr. 5, S. 2200388. https://doi.org/10.1183/13993003.00388-2022

TBnet, The ESGMYC, and The French MDR-TB Group 2022, 'Co-administration of treatment for rifampicin-resistant TB and chronic HCV infection: a TBnet and ESGMYC study', Journal of infection, Jg. 84, Nr. 6, S. 834-872. https://doi.org/10.1016/j.jinf.2022.03.004

Tran, F, Harris, DMM, Scharmacher, A, Graßhoff, H, Sterner, K, Schinke, S, Käding, N, Humrich, JY, Cabral-Marques, O, Bernardes, JP, Mishra, N, Bahmer, T, Franzenburg, J, Hoyer, BF, Glück, A, Guggeis, M, Ossysek, A, Küller, A, Frank, D, Lange, C, Rupp, J, Heyckendorf, J, Gaede, KI, Amital, H, Rosenstiel, P, Shoenfeld, Y, Halpert, G, Rosenberg, AZ, Schulze-Forster, K, Heidecke, H, Riemekasten, G & Schreiber, S 2022, 'Increased protease-activated receptor 1 autoantibodies are associated with severe COVID-19', ERJ Open Research, Jg. 8, Nr. 4. https://doi.org/10.1183/23120541.00379-2022

UNITE4TB Consortium 2022, 'Tuberculosis Treatment Monitoring and Outcome Measures: New Interest and New Strategies', Clinical microbiology reviews, Jg. 35, Nr. 3, S. e0022721. https://doi.org/10.1128/cmr.00227-21

 

2021

Benet, S, Gálvez, C, Drobniewski, F, Kontsevaya, I, Arias, L, Monguió-Tortajada, M, Erkizia, I, Urrea, V, Ong, R-Y, Luquin, M, Dupont, M, Chojnacki, J, Dalmau, J, Cardona, P, Neyrolles, O, Lugo-Villarino, G, Vérollet, C, Julián, E, Furrer, H, Günthard, HF, Crocker, PR, Tapia, G, Borràs, FE, Fellay, J, McLaren, PJ, Telenti, A, Cardona, P-J, Clotet, B, Vilaplana, C, Martinez-Picado, J & Izquierdo-Useros, N 2021, 'Dissemination of Mycobacterium tuberculosis is associated to a SIGLEC1 null variant that limits antigen exchange via trafficking extracellular vesicles', Journal of extracellular vesicles, Jg. 10, Nr. 3, S. e12046. https://doi.org/10.1002/jev2.12046

Boeree, MJ, Lange, C, Thwaites, G, Paton, N, de Vrueh, R, Barros, D & Hoelscher, M 2021, 'UNITE4TB: a new consortium for clinical drug and regimen development for TB', INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Jg. 25, Nr. 11, S. 886-889. https://doi.org/10.5588/ijtld.21.0515

Brandenburg, J, Marwitz, S, Tazoll, SC, Waldow, F, Kalsdorf, B, Vierbuchen, T, Scholzen, T, Gross, A, Goldenbaum, S, Hölscher, A, Hein, M, Linnemann, L, Reimann, M, Kispert, A, Leitges, M, Rupp, J, Lange, C, Niemann, S, Behrends, J, Goldmann, T, Heine, H, Schaible, UE, Hölscher, C, Schwudke, D & Reiling, N 2021, 'WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis', Journal of Clinical Investigation, Jg. 131, Nr. 16, e141833. https://doi.org/10.1172/JCI141833

Chesov, D, Butov, D, Reimann, M, Heyckendorf, J, Myasoedov, V, Butov, T, Akymenko, O & Lange, C 2021, 'Impact of lung function on treatment outcome in patients with TB', INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Jg. 25, Nr. 4, S. 277-284. https://doi.org/10.5588/ijtld.20.0949

Chesov, D, Heyckendorf, J, Alexandru, S, Donica, A, Chesov, E, Reiman, M, Crudu, V, Botnaru, V & Lange, C 2021, 'Impact of bedaquiline on treatment outcomes of multidrug-resistant tuberculosis in a high-burden country', The European respiratory journal, Jg. 57, Nr. 6, 2002544. https://doi.org/10.1183/13993003.02544-2020

Chesov, D, Makhanda, G & Furin, J 2021, 'Tackling the many layers of stigma is essential for the "End TB Strategy"', INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Jg. 25, Nr. 9, S. 683-684. https://doi.org/10.5588/ijtld.21.0338

Chesov, E, Chesov, D, Maurer, FP, Andres, S, Utpatel, C, Barilar, I, Donica, A, Reimann, M, Niemann, S, Lange, C, Crudu, V, Heyckendorf, J & Merker, M 2021, 'Emergence of bedaquiline-resistance in a high-burden country of tuberculosis', The European respiratory journal. https://doi.org/10.1183/13993003.00621-2021

Correa-Macedo, W, Fava, VM, Orlova, M, Cassart, P, Olivenstein, R, Sanz, J, Xu, YZ, Dumaine, A, Sindeaux, RH, Yotova, V, Pacis, A, Girouard, J, Kalsdorf, B, Lange, C, Routy, J-P, Barreiro, LB & Schurr, E 2021, 'Alveolar macrophages from persons living with HIV show impaired epigenetic response to Mycobacterium tuberculosis', Journal of Clinical Investigation, Jg. 131, Nr. 22. https://doi.org/10.1172/JCI148013

COVID-19 Aachen Study (COVAS) 2021, 'Swarm Learning for decentralized and confidential clinical machine learning', NATURE, Jg. 594, Nr. 7862, S. 265-270. https://doi.org/10.1038/s41586-021-03583-3

COVID-19 Host Genetics Initiative, Lange, C, Heyckendorf, J & Gaede, KI 2021, 'Mapping the human genetic architecture of COVID-19', NATURE. https://doi.org/10.1038/s41586-021-03767-x

COVID-Piacenza Group, Guglielmetti, L, Kontsevaya, I, Leoni, MC, Ferrante, P, Fronti, E, Gerna, L, Valdatta, C, Donisi, A, Faggi, A, Paolillo, F, Ratti, G, Ruggieri, A, Scotti, M, Sacchini, D, Taliani, G & Codeluppi, M 2021, 'Severe COVID-19 pneumonia in Piacenza, Italy - A cohort study of the first pandemic wave', Journal of Infection and Public Health, Jg. 14, Nr. 2, S. 263-270. https://doi.org/10.1016/j.jiph.2020.11.012

DiNardo, AR, Nishiguchi, T, Grimm, SL, Schlesinger, LS, Graviss, EA, Cirillo, JD, Coarfa, C, Mandalakas, AM, Heyckendorf, J, Kaufmann, SHE, Lange, C, Netea, MG & Van Crevel, R 2021, 'Tuberculosis endotypes to guide stratified host-directed therapy', Med (New York, N.Y.), Jg. 2, Nr. 3, S. 217-232. https://doi.org/10.1016/j.medj.2020.11.003

Du, X, Larsen, J, Li, M, Walter, A, Slavetinsky, C, Both, A, Sanchez Carballo, PM, Stegger, M, Lehmann, E, Liu, Y, Liu, J, Slavetinsky, J, Duda, KA, Krismer, B, Heilbronner, S, Weidenmaier, C, Mayer, C, Rohde, H, Winstel, V & Peschel, A 2021, 'Staphylococcus epidermidis clones express Staphylococcus aureus-type wall teichoic acid to shift from a commensal to pathogen lifestyle', Nature Microbiology, Jg. 6, Nr. 6, S. 757-768. https://doi.org/10.1038/s41564-021-00913-z

DZIF-TB cohort study group, Heyckendorf, J, Reimann, M, Marwitz, S & Lange, C 2021, 'Pathogen-free diagnosis of tuberculosis', Lancet Infectious Diseases, Jg. 21, Nr. 8, S. 1066. https://doi.org/10.1016/S1473-3099(21)00337-6

Feuerriegel, S, Kohl, TA, Utpatel, C, Andres, S, Maurer, FP, Heyckendorf, J, Jouet, A, Badalato, N, Foray, L, Kamara, RF, Conteh, OS, Supply, P & Niemann, S 2021, 'Rapid genomic first- and second-line drug resistance prediction from clinical Mycobacterium tuberculosis specimens using Deeplex®-MycTB', The European respiratory journal, Jg. 57, Nr. 1. https://doi.org/10.1183/13993003.01796-2020

Goldmann, T, Hillemann, D, Maurer, F, Kalsdorf, B, Krupar, R, Stellmacher, F & Perner, S 2021, 'Mycobacterium szulgai als Posititivkontrolle zur Detektion von Kontaminationen beim Nachweis des Mycobacterium tuberculosis-Komplexes durch eine spezifische 16S-rDNA-PCR an FFPE-Material', Der Pathologe, Jg. 42, Nr. 1, S. 83-85. https://doi.org/10.1007/s00292-021-00912-1

Grobbel, H-P, Merker, M, Köhler, N, Andres, S, Hoffmann, H, Heyckendorf, J, Reimann, M, Barilar, I, Dreyer, V, Hillemann, D, Kalsdorf, B, Kohl, TA, Sanchez-Carballo, P, Schaub, D, Todt, K, Utpatel, C, Maurer, FP, Lange, C & Niemann, S 2021, 'Design of multidrug-resistant tuberculosis treatment regimens based on DNA sequencing', CLINICAL INFECTIOUS DISEASES , Jg. 73, Nr. 7, S. 1194-1202. https://doi.org/10.1093/cid/ciab359

Guglielmetti, L, Aschieri, D, Kontsevaya, I, Calabrese, F, Donisi, A, Faggi, A, Ferrante, P, Fronti, E, Gerna, L, Leoni, MC, Paolillo, F, Ratti, G, Ruggieri, A, Sacchini, D, Scotti, M, Valdatta, C, Stabile, M, Taliani, G & Codeluppi, M 2021, 'Treatment for COVID-19-a cohort study from Northern Italy', Scientific Reports, Jg. 11, Nr. 1, 20964. https://doi.org/10.1038/s41598-021-00243-4

Günther, G, Heyckendorf, J, Zellweger, JP, Reimann, M, Claassens, M, Chesov, D & van Leth, F 2021, 'Defining Outcomes of Tuberculosis (Treatment): From the Past to the Future', RESPIRATION, Jg. 100, Nr. 9, S. 843-852. https://doi.org/10.1159/000516392

Heyckendorf, J, Marwitz, S, Reimann, M, Avsar, K, DiNardo, A, Günther, G, Hoelscher, M, Ibraim, E, Kalsdorf, B, Kaufmann, SHE, Kontsevaya, I, van Leth, F, Mandalakas, AM, Maurer, FP, Müller, M, Nitschkowski, D, Olaru, ID, Popa, C, Rachow, A, Rolling, T, Rybniker, J, Salzer, HJF, Sanchez-Carballo, P, Schuhmann, M, Schaub, D, Spinu, V, Suárez, I, Terhalle, E, Unnewehr, M, Weiner, J, Goldmann, T & Lange, C 2021, 'Prediction of anti-tuberculosis treatment duration based on a 22-gene transcriptomic model', The European respiratory journal, Jg. 58, Nr. 3. https://doi.org/10.1183/13993003.03492-2020

Hillery, N, Seifert, M, Catanzaro, DG, McKinnon, S, Colman, RE, Chiles, PG, Chesov, D, Ciobanu, N, Hagan, C, Crudu, V, Catanzaro, A & Rodwell, TC 2021, 'Rapid Detection of Extensively Drug-Resistant Tuberculosis in Clinical Samples Using a Novel Tabletop Platform:Protocol for a Prospective Clinical Study', JMIR research protocols, Jg. 10, Nr. 7, S. e26748. https://doi.org/10.2196/26748

Koegelenberg, CFN, Schoch, OD & Lange, C 2021, 'Tuberculosis: The Past, the Present and the Future', RESPIRATION, Jg. 100, Nr. 7, S. 553-556. https://doi.org/10.1159/000516509

Kontsevaya, I, Lange, C, Comella-Del-Barrio, P, Coarfa, C, DiNardo, AR, Gillespie, SH, Hauptmann, M, Leschczyk, C, Mandalakas, AM, Martinecz, A, Merker, M, Niemann, S, Reimann, M, Rzhepishevska, O, Schaible, UE, Scheu, KM, Schurr, E, Abel Zur Wiesch, P & Heyckendorf, J 2021, 'Perspectives for systems biology in the management of tuberculosis', European Respiratory Review, Jg. 30, Nr. 160. https://doi.org/10.1183/16000617.0377-2020

Kuempers, C, Jagomast, T, Krupar, R, Paulsen, F-O, Heidel, C, Ribbat-Idel, J, Idel, C, Märkl, B, Anlauf, M, Berezowska, S, Tiemann, M, Bösmüller, H, Fend, F, Kalsdorf, B, Bohnet, S, Dreyer, E, Sailer, V, Kirfel, J & Perner, S 2021, 'Delta-Like Protein 3 Expression in Paired Chemonaive and Chemorelapsed Small Cell Lung Cancer Samples', Frontiers in Medicine, Jg. 8, S. 734901. https://doi.org/10.3389/fmed.2021.734901

Kümpers, C, Tharun, L, Stellmacher, F, Greinert, U, May, K & Perner, S 2021, 'IgG4-assoziierte Lungenerkrankung mit granulomatösen Läsionen: Koexistenz zweier Entitäten oder das Spektrum einer Erkrankung?', Der Pathologe, Jg. 42, Nr. 1, S. 95-101. https://doi.org/10.1007/s00292-020-00904-7

Lange, C, Aaby, P, Behr, MA, Donald, PR, Kaufmann, SHE, Netea, MG & Mandalakas, AM 2021, '100 years of Mycobacterium bovis bacille Calmette-Guérin', Lancet Infectious Diseases. https://doi.org/10.1016/S1473-3099(21)00403-5

Lange, C, Chesov, D, Konstatynovska, O, Mandalakas, A-M & Udwadia, Z 2021, 'Sorry for the delay', CLINICAL MICROBIOLOGY AND INFECTION , Jg. 27, Nr. 7, S. 941-943. https://doi.org/10.1016/j.cmi.2021.03.007

Mandalakas, AM, Hesseling, AC, Kay, A, Du Preez, K, Martinez, L, Ronge, L, DiNardo, A, Lange, C & Kirchner, HL 2021, 'Tuberculosis prevention in children: A prospective community based study in South Africa', The European respiratory journal, Jg. 57, Nr. 4, 20030857. https://doi.org/10.1183/13993003.03028-2020

Mika, T, Vangala, D, Eckhardt, M, La Rosée, P, Lange, C, Lehmberg, K, Wohlschläger, C, Biskup, S, Fuchs, I, Mann, J, Ehl, S, Warnatz, K & Schroers, R 2021, 'Case Report: Hemophagocytic Lymphohistiocytosis and Non-Tuberculous Mycobacteriosis Caused by a Novel GATA2 Variant', FRONTIERS IN IMMUNOLOGY, Jg. 12, S. 682934. https://doi.org/10.3389/fimmu.2021.682934

Molina-Moya, B, Guglielmetti, L, Bothamley, G, van Leth, F, Lange, C & Dominguez, J 2021, 'Use and impact of molecular methods for detecting drug-resistant TB', INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Jg. 25, Nr. 2, S. 157-159. https://doi.org/10.5588/ijtld.20.0527

Pfeuffer-Jovic, E, Heyckendorf, J, Reischl, U, Bohle, RM, Bley, T, Buck, A, Wilkens, H, Schäfers, H-J, Langen, H-J & Held, M 2021, 'Pulmonary vasculitis due to infection with Mycobacterium goodii: a case report', INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES , Jg. 104, S. 178-180. https://doi.org/10.1016/j.ijid.2020.12.074

Roelens, M, Battista Migliori, G, Rozanova, L, Estill, J, Campbell, JR, Cegielski, JP, Tiberi, S, Palmero, D, Fox, GJ, Guglielmetti, L, Sotgiu, G, Brust, JCM, Bang, D, Lange, C, Menzies, D, Keiser, O & Raviglione, M 2021, 'Evidence-based Definition for Extensively Drug-resistant Tuberculosis', American journal of respiratory and critical care medicine, Jg. 204, Nr. 6, S. 713-722. https://doi.org/10.1164/rccm.202009-3527OC

Sachsenweger, J, Scheu, KM, Lange, C & Terhalle, E 2021, '24/w mit chronischem Husten: Vorbereitung auf die Facharztprüfung: Fall 45', Internist, Jg. 62, Nr. Suppl 3, S. 315-321. https://doi.org/10.1007/s00108-021-01005-0

Sachsenweger, J, Scheu, KM, Lange, C & Terhalle, E 2021, '35/w mit zervikaler Lymphadenopathie: Vorbereitung auf die Facharztprüfung: Fall 32', Internist, Jg. 62, Nr. Suppl 3, S. 245-250. https://doi.org/10.1007/s00108-021-00998-y

Salzer, HJF, Massango, I, Bhatt, N, Machonisse, E, Reimann, M, Heldt, S, Lange, C, Hoelscher, M, Khosa, C & Rachow, A 2021, 'Seroprevalence of Aspergillus-Specific IgG Antibody among Mozambican Tuberculosis Patients', Journal of fungi (Basel, Switzerland), Jg. 7, Nr. 8. https://doi.org/10.3390/jof7080595

Schumacher, J, Lange, C, Kleinjohann, L & Carvalho, C 2021, 'Testing the Proper Fit Of Respirator Masks During the COVID-19 Pandemic', Deutsches Ärzteblatt International, Jg. 118, Nr. 14, S. 250-251. https://doi.org/10.3238/arztebl.m2021.0186

TB clin standards 2021, 'Clinical standards for the assessment, management and rehabilitation of post-TB lung disease', INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Jg. 25, Nr. 10, S. 797-813. https://doi.org/10.5588/ijtld.21.0425

 

2020

Bernardes JP, Mishra N, Tran F, Bahmer T, Best L, Blase JI, Bordoni D, Franzenburg J, Geisen U, Josephs-Spaulding J, Köhler P, Künstner A, Rosati E, Aschenbrenner AC, Bacher P, Baran N, Boysen T, Brandt B, Bruse N, Dörr J, Dräger A, Elke G, Ellinghaus D, Fischer J, Forster M, Franke A, Franzenburg S, Frey N, Friedrichs A, Fuß J, Glück A, Hamm J, Hinrichsen F, Hoeppner MP, Imm S, Junker R, Kaiser S, Kan YH, Knoll R, Lange C, Laue G, Lier C, Lindner M, Marinos G, Markewitz R,  Nattermann J, Noth R, Pickkers P, Rabe KF, Renz A, Röcken C, Rupp J, Schaffarzyk A, Scheffold A, Schulte-Schrepping J, Schunk D, Skowasch D, Ulas T, Wandinger KP, Wittig M, Zimmermann J, Busch H, Hoyer BF, Kaleta C, Heyckendorf J, Kox M, Rybniker J, Schreiber S, Schultze JL, Rosenstiel P; HCA Lung Biological Network; Deutsche COVID-19 Omics Initiative (DeCOI), 'Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19', Immunity, 2020 Dec 15;53(6):1296-1314.e9. http://doi.org/10.1016/j.immuni.2020.11.017

Chesov D, Heyckendorf J, Alexandru S, Donica A, Chesov E, Reiman M, Crudu V, Botnaru V, Lange C, 'Impact of bedaquiline on treatment outcomes of multidrug-resistant tuberculosis in a high-burden country', European Respiratory Journal, 2020 Dec 17:2002544. http://doi.org/10.1183/13993003.02544-2020

Heyckendorf J, Gillespie SH, Ruhwald M, 'Culture-free proof of Mycobacterium tuberculosis - a new assay for viable bacteria', eBioMedicine, 2020 Dec;62:103117. http://doi.org/10.1016/j.ebiom.2020.103117

Nikolayevskyy V, Balabanova Y, Kontsevaya I, Ignatyeva O, Skenders G, Vasiliauskiene E, Bockel DV, Drobniewski F, 'Biomarkers of treatment success in fully sensitive pulmonary tuberculosis patients: a multicenter longitudinal study', Biomarkers in Medicine, 2020 Oct;14(15):1439-1452. http://doi.org/10.2217/bmm-2020-0246

Abidi, S, Achar, J, Neino, MMA, Bang, D, Benedetti, A, Brode, S, Campbell, JR, Casas, E, Conradie, F, Dravniece, G, du Cros, P, Falzon, D, Jaramillo, E, Kuaban, C, Lan, Z, Lange, C, Li, PZ, Makhmudova, M, Maug, AKJ, Menzies, D, Migliori, GB, Miller, A, Myrzaliev, B, Ndjeka, N, Noeske, J, Parpieva, N, Piubello, A, Schwoebel, V, Sikhondze, W, Singla, R, Souleymane, MB, Trébucq, A, Van Deun, A, Viney, K, Weyer, K, Zhang, BJ & Khan, FA 2020, 'Standardised shorter regimens versus individualised longer regimens for rifampin- or multidrug-resistant tuberculosis.', The European respiratory journal, Jg. 55, Nr. 3, 1901467. https://doi.org/10.1183/13993003.01467-2019

Andres, S, Merker, M, Heyckendorf, J, Kalsdorf, B, Rumetshofer, R, Indra, A, Hofmann-Thiel, S, Hoffmann, H, Lange, C, Niemann, S & Maurer, FP 2020, 'Bedaquiline-resistant Tuberculosis:Dark Clouds on the Horizon', American journal of respiratory and critical care medicine, Jg. 201, Nr. 12, S. 1564-1568. https://doi.org/10.1164/rccm.201909-1819LE

Bisson GP, Bastos M, Campbell JR, Bang D, Brust JC, Isaakadis P, Lange C, Menzies D, Migliori GB, Pape JW, Palmero D, Baghei P, Tabarsi P, Viiklepp P, Vilbrun S, Walsh J, Marks SM, 'Mortality in adults with multidrug-resistant tuberculosis and HIV by antiretroviral therapy and tuberculosis drug use: an individual patient data meta-analysis', The Lancet, 2020 Aug 8;396(10248):402-411. http://doi.org/10.1016/S0140-6736(20)31316-7

Butov, D, Lange, C, Heyckendorf, J, Kalmykova, I, Butova, T, Borovok, N, Novokhatskaya, M & Chesov, D 2020, 'Multidrug-resistant tuberculosis in the Kharkiv Region, Ukraine', INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Jg. 24, Nr. 5, S. 485-491. https://doi.org/10.5588/ijtld.19.0508

Cresswell F, Lange C, van Crevel R, 'Improving the diagnosis of tuberculous meningitis: good, but not good enough', Clinical Microbiology and Infection, 2020 Feb;26(2):134-136. http://doi.org/10.1016/j.cmi.2019.10.009

Collaborative Group for the Meta-Analysis of Individual Patient Data in MDR-TB treatment 2017 2020, 'Drug-associated adverse events in the treatment of multidrug-resistant tuberculosis: an individual patient data meta-analysis', Lancet Respiratory Medicine, Jg. 8, Nr. 4, S. 383-394. https://doi.org/10.1016/S2213-2600(20)30047-3

Daley CL, Iaccarino JM, Lange C, Cambau E, Wallace RJ Jr, Andrejak C, Böttger EC, Brozek J, Griffith DE, Guglielmetti L, Huitt GA, Knight SL, Leitman P, Marras TK, Olivier KN, Santin M, Stout JE, Tortoli E, van Ingen J, Wagner D, Winthrop KL, 'Treatment of nontuberculous mycobacterial pulmonary disease: an official ATS/ERS/ESCMID/IDSA clinical practice guideline', European Respiratory Journal. 2020 Jul 7;56(1):2000535. http://doi.org/10.1183/13993003.00535-2020

Daley, CL, Iaccarino, JM, Lange, C, Cambau, E, Wallace, RJ, Andrejak, C, Böttger, EC, Brozek, J, Griffith, DE, Guglielmetti, L, Huitt, GA, Knight, SL, Leitman, P, Marras, TK, Olivier, KN, Santin, M, Stout, JE, Tortoli, E, van Ingen, J, Wagner, D & Winthrop, KL 2020, 'Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline', Clinical Infectious Deseases, Jg. 71, Nr. 4, S. 905-913. https://doi.org/10.1093/cid/ciaa1125

Eggeling, J, Heyckendorf, J, Lange, C, Maier, C, Reimann, M, Sassmann-Schweda, A, Shaikh, R, Herzmann, C & Luethgen, M 2020, 'Changes in taste and smell as an early marker for COVID-19', INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES , Jg. 99, S. 8-9. https://doi.org/10.1016/j.ijid.2020.07.018

Feuerriegel, S, Kohl, TA, Utpatel, C, Andres, S, Maurer, FP, Heyckendorf, J, Jouet, A, Badalato, N, Foray, L, Kamara, RF, Conteh, OS, Supply, P & Niemann, S 2020, 'Rapid genomic first- and second-line drug resistance prediction from clinical Mycobacterium tuberculosis specimens using Deeplex®-MycTB', The European respiratory journal. https://doi.org/10.1183/13993003.01796-2020

Gupta, RK, Calderwood, CJ, Yavlinsky, A, Krutikov, M, Quartagno, M, Aichelburg, MC, Altet, N, Diel, R, Dobler, CC, Dominguez, J, Doyle, JS, Erkens, C, Geis, S, Haldar, P, Hauri, AM, Hermansen, T, Johnston, JC, Lange, C, Lange, B, van Leth, F, Muñoz, L, Roder, C, Romanowski, K, Roth, D, Sester, M, Sloot, R, Sotgiu, G, Woltmann, G, Yoshiyama, T, Zellweger, J-P, Zenner, D, Aldridge, RW, Copas, A, Rangaka, MX, Lipman, M, Noursadeghi, M & Abubakar, I 2020, 'Discovery and validation of a personalized risk predictor for incident tuberculosis in low transmission settings', NATURE MEDICINE , Jg. 26, Nr. 12, S. 1941-1949. https://doi.org/10.1038/s41591-020-1076-0

Homolka, S, Paulowski, L, Andres, S, Hillemann, D, Jou, R, Günther, G, Claassens, M, Kuhns, M, Niemann, S & Maurer, FP 2020, 'Two Pandemics, One Challenge-Leveraging Molecular Test Capacity of Tuberculosis Laboratories for Rapid COVID-19 Case-Finding', EMERGING INFECTIOUS DISEASES, Jg. 26, Nr. 11. https://doi.org/10.3201/eid2611.202602

Izquierdo-Garcia, JL, Comella-Del-Barrio, P, Campos-Olivas, R, Villar-Hernández, R, Prat-Aymerich, C, De Souza-Galvão, ML, Jiménez-Fuentes, MA, Ruiz-Manzano, J, Stojanovic, Z, González, A, Serra-Vidal, M, García-García, E, Muriel-Moreno, B, Millet, JP, Molina-Pinargote, I, Casas, X, Santiago, J, Sabriá, F, Martos, C, Herzmann, C, Ruiz-Cabello, J & Domínguez, J 2020, 'Discovery and validation of an NMR-based metabolomic profile in urine as TB biomarker', Scientific Reports, Jg. 10, Nr. 1, S. 22317. https://doi.org/10.1038/s41598-020-78999-4

Joean, O, Thiele, T, Schütz, K, Schwerk, N, Sedlacek, L, Kalsdorf, B, Baumann, U & Stoll, M 2020, 'Multidrug-resistant Mycobacterium tuberculosis:a report of cosmopolitan microbial migration and an analysis of best management practices', BMC INFECTIOUS DISEASES , Jg. 20, Nr. 1, S. 678. https://doi.org/10.1186/s12879-020-05381-0

Jünger, C, Reimann, M, Krabbe, L, Gaede, KI, Lange, C, Herzmann, C & Rüller, S 2020, 'Non-invasive ventilation with pursed lips breathing mode for patients with COPD and hypercapnic respiratory failure: A retrospective analysis', PLOS ONE, Jg. 15, Nr. 9, S. e0238619. https://doi.org/10.1371/journal.pone.0238619

Kontsevaya I, Werngren J, Holicka Y, Klaos K, Tran A, Nikolayevskyy V, 'Non-commercial phenotypic assays for the detection of Mycobacterium tuberculosis drug resistance: a systematic review', European Journal of Clinical Microbiology & Infectious Diseases, 2020 Mar;39(3):415-426. http://doi.org/10.1007/s10096-019-03723-8

Kwak, N, Winters, N, Campbell, JR, Chan, ED, Gegia, M, Lange, C, Lee, M, Milanov, V, Menzies, D & Yim, J-J 2020, 'Changes in treatment for multidrug-resistant tuberculosis according to national income', The European respiratory journal, Jg. 56, Nr. 5. https://doi.org/10.1183/13993003.01394-2020

Lange C, Dheda K, Chesov D, Mandalakas AM, Udwadia Z, Horsburgh CR Jr, 'Challenging the management of drug-resistant tuberculosis - Authors' reply', The Lancet. 2020 Mar 7;395(10226):783-784. http://doi.org/10.1016/S0140-6736(20)30055-6

Lange, C, Aarnoutse, R, Chesov, D, van Crevel, R, Gillespie, SH, Grobbel, H-P, Kalsdorf, B, Kontsevaya, I, van Laarhoven, A, Nishiguchi, T, Mandalakas, A, Merker, M, Niemann, S, Köhler, N, Heyckendorf, J, Reimann, M, Ruhwald, M, Sanchez-Carballo, P, Schwudke, D, Waldow, F & DiNardo, AR 2020, 'Perspective for Precision Medicine for Tuberculosis', FRONTIERS IN IMMUNOLOGY, Jg. 11, S. 566608. https://doi.org/10.3389/fimmu.2020.566608

Lan Z, Ahmad N, Baghaei P, Barkane L, Benedetti A, Brode SK, Brust JCM, Campbell JR, Chang VWL, Falzon D, Guglielmetti L, Isaakidis P, Kempker RR, Kipiani M, Kuksa L, Lange C, Laniado-Laborín R, Nahid P, Rodrigues D, Singla R, Udwadia ZF, Menzies D; Collaborative Group for the Meta-Analysis of Individual Patient Data in MDR-TB treatment 2017, 'Drug-associated adverse events in the treatment of multidrug-resistant tuberculosis: an individual patient data meta-analysis', The Lancet Respiratory Medicine, 2020 Apr;8(4):383-394. http://doi.org/10.1016/S2213-2600(20)30047-3

Luethgen M, Eggeling J, Heyckendorf J, Lange C, Maier C, Reimann M, Sassmann-Schweda A, Shaikh R, Herzmann C, 'Changes in taste and smell as an early marker for COVID-19', International Journal of Infectious Diseases, 2020 Jul 21:S1201-9712(20)30562-2. http://doi.org/10.1016/j.ijid.2020.07.018

Martinez L, Cords O, Horsburgh CR, Andrews JR; Pediatric TB Contact Studies Consortium, 'The risk of tuberculosis in children after close exposure: a systematic review and individual-participant meta-analysis', The Lancet, 2020 Mar 21;395(10228):973-984. http://doi.org/10.1016/S0140-6736(20)30166-5

Naik, SK, Pattanaik, K, Eich, J, Sparr, V, Hauptmann, M, Kalsdorf, B, Reiling, N, Liedtke, W, Kuebler, WM, Schaible, UE & Sonawane, A 2020, 'Differential Roles of the Calcium Ion Channel TRPV4 in Host Responses to Mycobacterium tuberculosis Early and Late in Infection', iScience, Jg. 23, Nr. 6, S. 101206. https://doi.org/10.1016/j.isci.2020.101206

Nikolayevskyy, V, Balabanova, Y, Kontsevaya, I, Ignatyeva, O, Skenders, G, Vasiliauskiene, E, Bockel, DV & Drobniewski, F 2020, 'Biomarkers of treatment success in fully sensitive pulmonary tuberculosis patients: a multicenter longitudinal study', Biomarkers in medicine, Jg. 14, Nr. 15, S. 1439-1452. https://doi.org/10.2217/bmm-2020-0246

NTM-NET 2020, 'Epidemiology of nontuberculous mycobacterial pulmonary disease in Europe and Japan by Delphi estimation', RESPIRATORY MEDICINE , Jg. 173, S. 106164. https://doi.org/10.1016/j.rmed.2020.106164

Otto-Knapp, R, Knappik, M, Häcker, B, Starzacher, K, Bauer, T, Lange, C, Maurer, FP, Schaberg, T & Günther, G 2020, 'Die neuen WHO-Empfehlungen für schnelle Diagnostik und Therapie resistenter Tuberkulose in Deutschland, Österreich und der Schweiz', Pneumologie (Stuttgart, Germany), Jg. 74, Nr. 11, S. 742-749. https://doi.org/10.1055/a-1266-5207

Pediatric TB Contact Studies Consortium & Lange, C 2020, 'The risk of tuberculosis in children after close exposure: a systematic review and individual-participant meta-analysis', Lancet, Jg. 395, Nr. 10228, S. 973-984. https://doi.org/10.1016/S0140-6736(20)30166-5

Suárez, I, Gruell, H, Heyckendorf, J, Fünger, S, Lichtenstein, T, Jung, N, Lehmann, C, Unnewehr, M, Fätkenheuer, G, Lange, C & Rybniker, J 2020, 'Intensified adjunctive corticosteroid therapy for CNS tuberculomas', Infection. https://doi.org/10.1007/s15010-019-01378-3

Udwadia, ZF, Vora, A, Tripathi, AR, Malu, KN, Lange, C & Sara Raju, R 2020, 'COVID-19 -Tuberculosis interactions: When dark forces collide', The Indian journal of tuberculosis, Jg. 67, Nr. 4S, S. S155-S162. https://doi.org/10.1016/j.ijtb.2020.07.003

Wagner, D & Lange, C 2020, 'Lungenerkrankung durch nicht-tuberkulöse Mykobakterien – Die neue ATS/ERS/ESCMID/IDSA-Leitlinie', Deutsche medizinische Wochenschrift (1946), Jg. 145, Nr. 16, S. 1145-1151. https://doi.org/10.1055/s-0043-124159

Wollenberg, K, Harris, M, Gabrielian, A, Ciobanu, N, Chesov, D, Long, A, Taaffe, J, Hurt, D, Rosenthal, A, Tartakovsky, M & Crudu, V 2020, 'A retrospective genomic analysis of drug-resistant strains of M. tuberculosis in a high-burden setting, with an emphasis on comparative diagnostics and reactivation and reinfection status', BMC INFECTIOUS DISEASES , Jg. 20, Nr. 1, S. 17. https://doi.org/10.1186/s12879-019-4739-z